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Monomers

Bisphenol A

Also known as 2,2-Bis(4-hydroxyphenyl)propane, Bisphenol, Diano

CAS 80-05-7Formula C15H16O2Molar mass 228.29 g/molEC 201-245-8
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant, Serious health hazard, Hazardous to the environment 235 suppliers listed
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Bisphenol A chemical structure, C15H16O2, CAS 80-05-7
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystallizes as prisms from dil acetic acid and as needles from water
Melting point
160 °C
Boiling point
360.5 °C
Density
Relative density (water = 1): 1.2 (25 °C)
Flash point
227 °C
HS code
290723
Category
Monomers
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Bisphenol A?

Plain description, key identifiers and synonyms

Bisphenol A is a bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups. It has a role as an endocrine disruptor, a xenobiotic, a xenoestrogen and an environmental contaminant.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
CAS number
80-05-7 CAS number cross-checked
EC number
201-245-8
Molecular formula
C15H16O2
UNII
MLT3645I99
MDL number
MFCD00002366
INCI name
4,4'-ISOPROPYLIDENEDIPHENOL
InChIKey
IISBACLAFKSPIT-UHFFFAOYSA-N
InChI
InChI=1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3
SMILES (canonical and isomeric)
CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)O

Synonyms

  • 2,2-Bis(4-hydroxyphenyl)propane
  • Bisphenol
  • Diano
  • 4,4'-Isopropylidenediphenol
  • 4,4'-(propane-2,2-diyl)diphenol
  • Diphenylolpropane
  • 4,4'-Bisphenol A
  • 2,2-Bis(p-hydroxyphenyl)propane
  • Parabis A
  • DIAN
  • Rikabanol
  • Bisphenol-A
  • Biphenol A
  • Ipognox 88
  • p,p'-Bisphenol A
  • Pluracol 245
  • Bisferol A
  • p,p'-Isopropylidenebisphenol
  • 2,2-Di(4-phenylol)propane
  • 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
  • p,p'-Dihydroxydiphenylpropane
  • 4,4'-(1-Methylethylidene)bisphenol
  • 4,4'-Dihydroxydiphenylpropane
  • Ucar bisphenol A
  • Dimethylmethylene-p,p'-diphenol
Show all 39 synonyms
  • p,p'-Isopropylidenediphenol
  • Bis(4-hydroxyphenyl)propane
  • Ucar bisphenol HP
  • Phenol, 4,4'-(1-methylethylidene)bis-
  • 2,2-Di(4-hydroxyphenyl)propane
  • 4,4'-Isopropylidene diphenol
  • 2,2-Bis(hydroxyphenyl)propane
  • p,p'-Dihydroxydiphenyldimethylmethane
  • 4,4'-Isopropylidenebisphenol
  • Bis(4-hydroxyphenyl)dimethylmethane
  • Isopropylidenebis(4-hydroxybenzene)
  • Bis(4-hydroxyphenyl) dimethylmethane
  • 4,4'-Dihydroxydiphenyldimethylmethane
  • 2,2-Bis-4'-hydroxyfenylpropan

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystallizes as prisms from dil acetic acid and as needles from waterexp.
Odour
Mild phenolic odorexp.
Melting point
160 °Cexp.
Boiling point
360.5 °Cexp.
Density
Relative density (water = 1): 1.2 (25 °C)exp.
Flash point
227 °Cexp.
Autoignition temperature
510 to 570exp.
Solubility
In water, 300 mg/L at 25 °Cexp.
Vapour pressure
4.0 × 10⁻⁸ mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
228.29 g/molcalc.
Exact mass
228.115 Dacalc.
LogP (octanol/water)
3.42calc.
Topological polar surface area
40.46 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
17calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.2calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cc2ccccc2)cc1

c1ccc(Cc2ccccc2)cc1

2 rings, 13 atoms, the Diphenylmethane ring system.

8,982 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H335May cause respiratory irritation.
  • H360FMay damage fertility.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bisphenol A suppliers

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All 235 suppliers
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Where suppliers are based

235 suppliers in 31 countries

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Bisphenol A price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

The largest use for bisphenol A is polycarbonate ... followed by epoxy resins. Other uses are flame retardants, unsaturated polyester resins and polyacrylate, polyetherimide, and polysulfone resins.

Used for a wide range of products such as aromatic polyesters with phthalic acid, polysulfones, polyetherketones, unsaturated, hydrolysis-resistant polyesters, antioxidants, phenoxy resins from bisphenol A and epichlorohydrin, and phenolic resins elastified by incorporation of bisphenol A. However, the majority is used for flame retardants, especially tetrabromobisphenol A.

Manufacture of thermal papers.

Fungicide (Former USA).

Industrial uses: Hydraulic fluids, Flame retardant, Filler, Hardener, Intermediate, Heat stabilizer, Surface modifier.

Consumer uses: Hydraulic fluids, Intermediate, Hardener, Binder, Monomers.

Industries and functions

Cosmetic ingredient, INCI name 4,4'-ISOPROPYLIDENEDIPHENOL(not reported)

Pharmacological actions

  • Air Pollutants, Occupational
  • Estrogens, Non-Steroidal
  • Free Radical Scavengers

Roles

  • agonist
  • endocrine disruptor
  • environmental contaminant
  • estrogen
  • hormone
  • hormone receptor modulator
  • molecular messenger
  • pharmaceutical
  • receptor modulator
  • sex hormone
  • xenobiotic
  • xenoestrogen

Functional uses

  • Antioxidant
  • Binder
  • Catalyst
  • Flame retardant
  • Hardener
  • Monomers

Cosmetic functions

  • Not reported

Pharmacology

Bisphenol A is a diphenylmethane derivative with two hydroxyphenyl groups. Bisphenol A (BPA) is a colorless solid that is used in the synthesis of commercial plastics, including polycarbonates and epoxy resins, which are incorporated into a wide variety of consumer goods. Ingested BPA may exhibit estrogenic effects. Exposure to BPA may increase the risk of certain cancers.

How it is made

Hydrogen chloride or sulfonated cross-linked polystyrenes are used as the catalyst which are usually arranged as a fixed bed over which the reaction mixture is passed. The reaction of phenol with acetone takes place at 50 - 90 °C, the molar ratio phenol - acetone is up to 15:1. Bisphenol A crystallizes as an adduct with 1 mol phenol, after separation of the hydrogen chloride by distillation or neutralization. The use of ion exchangers is preferred to that of hydrogen chloride because they are less corrosive. The yield is normally 80-95%.

Manufacture from phenol and acetone: Jansen, United States of America patent 2468982 (1949).

Condensation of two equivalent amounts of phenol with an aldehyde or ketone.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 604-030-00-0

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Bisphenol A (4,4'-Isopropylidenediphenol), Ref no: 1176, Annex ref: II/1176

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bisphenol A is traded under.

HS 2907.23Exact HS code

4,4′-Isopropylidenediphenol (bisphenol A, diphenylolpropane) and its salts

World exports in 2024
$535M
−9.2% vs 2023, imports $891M
2019 to 2024
Top exporters
  1. South Korea64.4%
  2. Thailand18.0%
  3. Netherlands7.6%
Top importers
  1. India * partner reported15.0%
  2. Thailand13.3%
  3. Japan12.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bisphenol A is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bisphenol A, based on the data on this page

What is Bisphenol A?

Bisphenol A is a bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups. It has a role as an endocrine disruptor, a xenobiotic, a xenoestrogen and an environmental contaminant.

What is the CAS number of Bisphenol A?

The CAS registry number of Bisphenol A is 80-05-7.

What is the molecular formula and weight of Bisphenol A?

The molecular formula of Bisphenol A is C15H16O2 and its molar mass is 228.29 g/mol.

What is Bisphenol A used for?

The largest use for bisphenol A is polycarbonate ... followed by epoxy resins. Other uses are flame retardants, unsaturated polyester resins and polyacrylate, polyetherimide, and polysulfone resins.

Is Bisphenol A hazardous?

Bisphenol A carries the GHS signal word "Danger". Main hazards: may cause an allergic skin reaction, causes serious eye damage, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bisphenol A?

Bisphenol A is usually classified under HS code 290723 (4,4′-Isopropylidenediphenol (bisphenol A, diphenylolpropane) and its salts). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bisphenol A?

CompoundList lists 235 suppliers of Bisphenol A in United States, India, China, Germany and 27 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bisphenol A in India?

52 suppliers in India list Bisphenol A on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bisphenol A?

Suppliers quote Bisphenol A on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bisphenol A

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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