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Skin conditioning agents and actives

Cannabinol

Also known as Cannabinolo, Cannabinolum, 6,6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol

CAS 521-35-7Formula C21H26O2Molar mass 310.44 g/molEC 689-788-0
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 9 suppliers listed
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Cannabinol chemical structure, C21H26O2, CAS 521-35-7
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Crystals
Melting point
76.1 to 77.2
Boiling point
185 °C
HS code
293299
Category
Skin conditioning agents and actives
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Cannabinol?

Plain description, key identifiers and synonyms

Cannabinol is a dibenzopyran.

Cannabinol is a naturally-occuring cannabinoid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol
CAS number
521-35-7 CAS number cross-checked
EC number
689-788-0
Molecular formula
C21H26O2
UNII
7UYP6MC9GH
INCI name
CANNABINOL
InChIKey
VBGLYOIFKLUMQG-UHFFFAOYSA-N
InChI
InChI=1S/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3
SMILES (canonical and isomeric)
CCCCCC1=CC(=C2C(=C1)OC(C3=C2C=C(C=C3)C)(C)C)O

Synonyms

  • Cannabinolo
  • Cannabinolum
  • 6,6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol
  • 6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol
  • 6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol
  • 3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo(b,d)pyran
  • 6H-Dibenzo(b,d)pyran-1-ol, 6,6,9-trimethyl-3-pentyl-
  • 3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
  • 6H-Dibenzo[b,d]pyran-1-ol, 6,6,9-trimethyl-3-pentyl-
  • 6,6,9-trimethyl-3-pentylbenzo(c)chromen-1-ol
  • Cannabinol (CBN)
  • 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol
  • 3-Amyl-1-hydroxy-6,6 ,9-trimethyl-6H-dibenzo[b,d]pyran
  • Cannabinol, 3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran, 6,6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol, CBN, NSC 134455, Cannabinoids
  • Cannabinol (6CI)
  • 6,6,9-Trimethyl-3-pent
  • 5-17-04-00567 (Beilstein Handbook Reference)
  • DivK1c_000972
  • Cannabinol, analytical standard
  • Cannabinol, 1mg/ml in Methanol
  • MeSH ID: D002187
  • Cannabinol 1.0 mg/ml in Methanol
  • Cannabinol - 20 mg/ml in methanol
  • R21AT012695-Cannabinoid-022
  • 6H-Dibenzo[b, 6,6,9-trimethyl-3-pentyl-
Show all 31 synonyms
  • Cannabinol (CBN) 100 microg/mL in Methanol
  • Cannabinol (CBN) 1000 microg/mL in Methanol
  • 6,6,9-trimethyl-3-pentyl-benzo[c]chromen-1-ol
  • Cannabinol (CBN) 250 microg/mL in Acetonitrile
  • 6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol
  • 3-Amyl-1-hydroxy-6,9-trimethyl-6H-dibenzo[b,d]pyran

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Crystalsexp.
Melting point
76.1 to 77.2exp.
Boiling point
185 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
310.44 g/molcalc.
Exact mass
310.1933 Dacalc.
LogP (octanol/water)
5.73calc.
Topological polar surface area
29.46 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
4calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.43calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)COc1ccccc1-2

c1ccc2c(c1)COc1ccccc1-2

3 rings, 14 atoms, the 6H-Benzo[c]chromene ring system.

44 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H361Suspected of damaging fertility or the unborn child.
  • H361dSuspected of damaging the unborn child.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (22)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cannabinol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 9 suppliers
9 of 9 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

9 suppliers in 5 countries

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Cannabinol price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Cosmetic ingredient, INCI name CANNABINOL(skin conditioning)

Roles

  • analgesic
  • anti-anaemic agent
  • anti-inflammatory agent
  • anti-obesity agent
  • anticonvulsant
  • antidepressant
  • antidyskinesia agent
  • antiglaucoma drug
  • antineoplastic agent
  • antiparkinson drug
  • antipsychotic agent
  • antirheumatic drug
  • antiviral agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • immunomodulator
  • immunosuppressive agent
  • neuroprotective agent
  • nootropic agent
  • ophthalmology drug
  • pharmaceutical
  • protective agent
  • psychotropic drug

Cosmetic functions

  • Skin conditioning

Pharmacology

Cannabinol is a cannabinoid isolated from the plant Cannabis that is a metabolite of tetrahydrocannabinol (THC), with potential immunosuppressive and anti-inflammatory activities. Cannabinol preferentially binds to the cannabinoid G-protein coupled receptor CB2, which is mainly expressed on a variety of immune cells, such as T-cells, B-cells, macrophages and dendritic cells. Stimulation of CB2 receptors by cannabinol may both trigger apoptosis in these cells and inhibit the production of a variety of cytokines. Cannabinol exerts minimal affinity for CB1 and has a weak effect on the central nervous system.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cannabinol is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cannabinol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cannabinol, based on the data on this page

What is Cannabinol?

Cannabinol is a dibenzopyran.

What is the CAS number of Cannabinol?

The CAS registry number of Cannabinol is 521-35-7.

What is the molecular formula and weight of Cannabinol?

The molecular formula of Cannabinol is C21H26O2 and its molar mass is 310.44 g/mol.

What is Cannabinol used for?

Use classes: Pharmaceuticals.

Is Cannabinol hazardous?

Cannabinol carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cannabinol?

Cannabinol is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cannabinol?

CompoundList lists 9 suppliers of Cannabinol in United States, China, France, India and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Cannabinol in India?

1 supplier in India list Cannabinol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Cannabinol?

Suppliers quote Cannabinol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cannabinol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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