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Skin conditioning agents and actives

Carnosine

Also known as L-Carnosine, beta-Alanyl-L-histidine, Ignotine

CAS 305-84-0Formula C9H14N4O3Molar mass 226.24 g/molEC 206-169-9
151 suppliers listed
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Carnosine chemical structure, C9H14N4O3, CAS 305-84-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
305-84-0
Formula
C9H14N4O3
Molar mass
226.24 g/mol
EC number
206-169-9
HS code
293329
Category
Skin conditioning agents and actives

What is Carnosine?

Plain description, key identifiers and synonyms

Carnosine is a dipeptide that is the N-(beta-alanyl) derivative of L-histidine. It has a role as a geroprotector, an antioxidant, an antineoplastic agent, an anticonvulsant, a neuroprotective agent, a mouse metabolite, a human metabolite and a Daphnia magna metabolite. It is a conjugate acid of a carnosinate. It is a tautomer of a carnosine zwitterion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid
CAS number
305-84-0 CAS number cross-checked
EC number
206-169-9
Molecular formula
C9H14N4O3
UNII
8HO6PVN24W
MDL number
MFCD00005207
INCI name
CARNOSINE
InChIKey
CQOVPNPJLQNMDC-ZETCQYMHSA-N
InChI
InChI=1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
Canonical SMILES
NCCC(=O)NC(Cc1cnc[nH]1)C(=O)O
Isomeric SMILES
C1=C(NC=N1)C[C@@H](C(=O)O)NC(=O)CCN

Synonyms

  • L-Carnosine
  • beta-Alanyl-L-histidine
  • Ignotine
  • Karnozin
  • Karnozzn
  • L-Histidine, beta-alanyl-
  • (2S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid
  • Nalpha-(beta-alanyl)-L-histidine
  • L-HISTIDINE, N-beta-ALANYL-
  • N-beta-alanyl-L-histidine
  • (2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid
  • (2S)-2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid
  • L Carnosine
  • beta Alanylhistidine
  • Hydrochloride, Carnosine
  • (2S)-2-(3-azaniumylpropanoylamino)-3-(1H-imidazol-5-yl)propanoate
  • (2S)-2-((3-Amino-1-Oxopropyl)Amino)-3-(3H-Imidazol-4-Yl)Propanoic Acid
  • (3-aminopropanoyl)-L-histidine
  • N-b-alanyl-L-Histidine
  • (S)-2-(3-Aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid
  • B-Ala-his-oh
  • (2S)-2-(3-aminopropanoylamino)-3-imidazol-4-ylpropanoic acid
  • (2~{S})-2-(3-azanylpropanoylamino)-3-(1~{H}-imidazol-4-yl)propanoic acid
  • Sevitin
  • betaAla-His
Show all 33 synonyms
  • L-Ignotine
  • b-Alanylhistidine
  • b-Alanyl-L-histidine
  • beta-alanyl-l-histidin
  • beta-Alanylhistidine
  • L-Carnosine (Standard)
  • 3-aminopropionyl-histidine
  • L-Histidine, |A-alanyl-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
226.24 g/molcalc.
Exact mass
226.1066 Dacalc.
LogP (octanol/water)
-1.13calc.
Topological polar surface area
121.1 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1c[nH]cn1

c1c[nH]cn1

1 ring, 5 atoms, the Imidazole ring system.

14,448 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Carnosine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 151 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

151 suppliers in 18 countries

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Carnosine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name CARNOSINE(skin conditioning)

Roles

  • Daphnia magna metabolite
  • Daphnia metabolite
  • animal metabolite
  • anticonvulsant
  • antineoplastic agent
  • antioxidant
  • antipsychotic agent
  • central nervous system depressant
  • central nervous system drug
  • crustacean metabolite
  • eukaryotic metabolite
  • geroprotector
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • neuroprotective agent
  • pharmaceutical
  • protective agent
  • psychotropic drug
  • tranquilizing drug

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Pharmacology

Carnosine is a dipeptide comprised of a beta-alanine and a 3-methyl-L-histidine, which is found in dietary red meat, with potential antioxidant, metal-chelating and anti-glycation activities. Carnosine scavenges both reactive oxygen species (ROS) and unsaturated aldehydes produced by cell membrane lipid peroxidation. Additionally, this dipeptide may reduce the rate of formation of advanced glycation end-products (AGE). Altogether, this may protect cells against oxidative damage. In addition, carnosine is able to chelate toxic metals.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Carnosine is traded under.

HS 2933.29Indicative HS code

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…

World exports in 2024
$1.43B
−7.6% vs 2023, imports $1.47B
2019 to 2024
Top exporters
  1. China28.1%
  2. France * partner reported12.7%
  3. India * partner reported10.3%
Top importers
  1. United Kingdom13.0%
  2. United States7.9%
  3. China6.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Carnosine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Carnosine, based on the data on this page

What is Carnosine?

Carnosine is a dipeptide that is the N-(beta-alanyl) derivative of L-histidine. It has a role as a geroprotector, an antioxidant, an antineoplastic agent, an anticonvulsant, a neuroprotective agent, a mouse metabolite, a human metabolite and a Daphnia magna metabolite. It is a conjugate acid of a carnosinate.

What is the CAS number of Carnosine?

The CAS registry number of Carnosine is 305-84-0.

What is the molecular formula and weight of Carnosine?

The molecular formula of Carnosine is C9H14N4O3 and its molar mass is 226.24 g/mol.

What is Carnosine used for?

Known uses and roles of Carnosine include skin conditioning agents in cosmetics and personal care, daphnia magna metabolite, daphnia metabolite, animal metabolite, anticonvulsant and 19 more.

Is Carnosine hazardous?

No GHS hazard classification for Carnosine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Carnosine?

Carnosine is usually classified under HS code 293329 (Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Carnosine?

CompoundList lists 151 suppliers of Carnosine in China, United States, Germany, Spain and 14 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Carnosine in India?

4 suppliers in India list Carnosine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Carnosine?

Suppliers quote Carnosine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Carnosine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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