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Screening compounds

Cc-115

Also known as Pyrazino[2,3-b]pyrazin-2(1H)-one, 1-ethyl-3,4-dihydro-7-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridinyl]-, 1-Ethyl-7-(2-methyl-6-(4H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, 1-Ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1H)-one

CAS 1228013-15-7Formula C16H16N8OMolar mass 336.36 g/mol
1 supplier listed
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Cc-115 chemical structure, C16H16N8O, CAS 1228013-15-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1228013-15-7
Formula
C16H16N8O
Molar mass
336.36 g/mol
HS code
293339
Category
Screening compounds

What is Cc-115?

Plain description, key identifiers and synonyms

DNA-PK/TOR Kinase Inhibitor CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC-115 binds to and inhibits the activity of DNA-PK and both raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK and TOR. DNA-PK, a serine/threonine kinase and a member of the PI3K-related kinase subfamily of protein kinases, is activated upon DNA damage and plays a key role in repairing double-stranded DNA breaks via the DNA nonhomologous end joining (NHEJ) pathway, mTOR, a serine/threonine kinase that is upregulated in a variety of tumors, plays an important role downstream in the PI3K/Akt/mTOR signaling pathway.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-ethyl-3-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridinyl]-7,8-dihydropyrazino[2,3-b]pyrazin-6-one
CAS number
1228013-15-7
Molecular formula
C16H16N8O
UNII
FII75TFH5L
MDL number
MFCD29036965
InChIKey
GMYLVKUGJMYTFB-UHFFFAOYSA-N
InChI
InChI=1S/C16H16N8O/c1-3-24-13(25)7-18-15-16(24)22-12(6-17-15)10-4-5-11(21-9(10)2)14-19-8-20-23-14/h4-6,8H,3,7H2,1-2H3,(H,17,18)(H,19,20,23)
SMILES (canonical and isomeric)
CCN1C(=O)CNC2=NC=C(N=C21)C3=C(N=C(C=C3)C4=NC=NN4)C

Synonyms

  • Pyrazino[2,3-b]pyrazin-2(1H)-one, 1-ethyl-3,4-dihydro-7-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridinyl]-
  • 1-Ethyl-7-(2-methyl-6-(4H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
  • 1-Ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1H)-one
  • 1-Ethyl-7-(2-methyl-6-(4H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1H)-one
  • 1-ethyl-7-[2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl]-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
  • Pyrazino(2,3-b)pyrazin-2(1H)-one, 1-ethyl-3,4-dihydro-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridinyl)-
  • DNA-PK/TOR Kinase Inhibitor CC-115
  • 1-ethyl-7-(2-methyl-6-(4H-1,2,4-triazol-3-yl)pyridin-3-yl)-1H,2H,3H,4H-(1,4)diazino(2,3-b)pyrazin-2-one
  • 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
  • 5-ethyl-3-[2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl]-7,8-dihydropyrazino[2,3-b]pyrazin-6-one
  • 4-ethyl-6-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridyl]-1,2-dihydropyrazino[2,3-b]pyrazin-3-one
  • CC-115?
  • CC-115, >98% (HPLC)
  • CC115, CC-115, CC 115
  • 1-ethyl-7-(2-methyl-6-(4H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,5-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
  • 1-Ethyl-7-[2-methyl-6-(1H-1,2,4-triazol-3-yl)-3-pyridinyl]-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
  • 1-ethyl-7-[2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl]-1H,2H,3H,4H-[1,4]diazino[2,3-b]pyrazin-2-one
  • 5-ethyl-3-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridyl]-7,8-dihydropyrazino[2,3-b]pyrazin-6-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
336.36 g/molcalc.
Exact mass
336.1447 Dacalc.
LogP (octanol/water)
1.41calc.
Topological polar surface area
112.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
3calc.
Heavy atoms
25calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CNc2ncc(-c3ccc(-c4ncn[nH]4)nc3)nc2N1

O=C1CNc2ncc(-c3ccc(-c4ncn[nH]4)nc3)nc2N1

4 rings, 22 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Cc-115 suppliers

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  • Sun-shine Chemical
    China, WuhanUnclaimed profile
    Cc-115Grade, purity and minimum order on request
    Price on request
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Cc-115 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cc-115 is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cc-115 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cc-115, based on the data on this page

What is Cc-115?

DNA-PK/TOR Kinase Inhibitor CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity.

What is the CAS number of Cc-115?

The CAS registry number of Cc-115 is 1228013-15-7.

What is the molecular formula and weight of Cc-115?

The molecular formula of Cc-115 is C16H16N8O and its molar mass is 336.36 g/mol.

What is Cc-115 used for?

Known uses and roles of Cc-115 include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent and pharmaceutical.

Is Cc-115 hazardous?

No GHS hazard classification for Cc-115 is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Cc-115?

Cc-115 is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cc-115?

CompoundList lists 1 supplier of Cc-115 in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Cc-115?

Suppliers quote Cc-115 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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