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Antibiotics and anti-infectives

Ceftiolene

Also known as Cefatiolene, Ceftiolenum, ceftioleno

CAS 77360-52-2Formula C20H18N8O8S3Molar mass 594.61 g/mol
1 supplier listed
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Ceftiolene chemical structure, C20H18N8O8S3, CAS 77360-52-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
77360-52-2
Formula
C20H18N8O8S3
Molar mass
594.61 g/mol
HS code
294190
Category
Antibiotics and anti-infectives

What is Ceftiolene?

Plain description, key identifiers and synonyms

Ceftiolene is a cephalosporin compound having (E)-2-{[5,6-dioxo-4-(2-oxoethyl)-1,4,5,6-tetrahydro-1,2,4-triazin-3-yl]sulfanyl}ethenyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups, a third-generation cephalosporin antibiotic. It has a role as an antibacterial drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(E)-2-[[5,6-dioxo-4-(2-oxoethyl)-1H-1,2,4-triazin-3-yl]sulfanyl]ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS number
77360-52-2 CAS number cross-checked
Molecular formula
C20H18N8O8S3
UNII
28TV2P33KF
InChIKey
WJXAHFZIHLTPFR-JLRJEBFFSA-N
InChI
InChI=1S/C20H18N8O8S3/c1-36-26-10(9-7-39-19(21)22-9)13(30)23-11-15(32)28-12(18(34)35)8(6-38-17(11)28)2-5-37-20-25-24-14(31)16(33)27(20)3-4-29/h2,4-5,7,11,17H,3,6H2,1H3,(H2,21,22)(H,23,30)(H,24,31)(H,34,35)/b5-2+,26-10-/t11-,17-/m1/s1
Canonical SMILES
CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(C=CSc3n[nH]c(=O)c(=O)n3CC=O)CSC12)c1csc(N)n1
Isomeric SMILES
CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)/C=C/SC4=NNC(=O)C(=O)N4CC=O)C(=O)O

Synonyms

  • Cefatiolene
  • Ceftiolenum
  • ceftioleno
  • RP 42980
  • RP 42,980

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
594.61 g/molcalc.
Exact mass
594.041 Dacalc.
LogP (octanol/water)
-1.44calc.
Topological polar surface area
232 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
14calc.
Rotatable bonds
10calc.
Heavy atoms
39calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, N=C(C(=O)NC1C(=O)N2C=C(C=CSc3n[nH]c(=O)c(=O)[nH]3)CSC12)c1cscn1

N=C(C(=O)NC1C(=O)N2C=C(C=CSc3n[nH]c(=O)c(=O)[nH]3)CSC12)c1cscn1

4 rings, 30 atoms.

No other chemical in our database has this scaffold.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Ceftiolene suppliers

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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

1 supplier in 1 country

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Ceftiolene price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • pharmaceutical

Pharmacology

Ceftiolene is a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Ceftiolene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ceftiolene is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ceftiolene is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ceftiolene, based on the data on this page

What is Ceftiolene?

Ceftiolene is a cephalosporin compound having (E)-2-{[5,6-dioxo-4-(2-oxoethyl)-1,4,5,6-tetrahydro-1,2,4-triazin-3-yl]sulfanyl}ethenyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups, a third-generation cephalosporin antibiotic. It has a role as an antibacterial drug.

What is the CAS number of Ceftiolene?

The CAS registry number of Ceftiolene is 77360-52-2.

What is the molecular formula and weight of Ceftiolene?

The molecular formula of Ceftiolene is C20H18N8O8S3 and its molar mass is 594.61 g/mol.

What is Ceftiolene used for?

Known uses and roles of Ceftiolene include antibacterials and antibiotics in pharmaceuticals, antibacterial agent, antibacterial drug, antiinfective agent, antimicrobial agent and 2 more.

Is Ceftiolene hazardous?

No GHS hazard classification for Ceftiolene is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Ceftiolene?

Ceftiolene is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ceftiolene?

CompoundList lists 1 supplier of Ceftiolene in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ceftiolene?

Suppliers quote Ceftiolene on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ceftiolene

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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