CompoundList

Chloroxine

Also known as 5,7-Dichloroquinolin-8-ol, 5,7-Dichloro-8-hydroxyquinoline, 5,7-Dichloro-8-quinolinol

Chloroxine chemical structure, C9H5Cl2NO, CAS 773-76-2
2D chemical structure

Key facts

What buyers check first

CAS number
773-76-2
Formula
C9H5Cl2NO
Molar mass
214.05 g/mol
EC number
212-258-3
HS code
293349
Category
Antibiotics and anti-infectives

What is Chloroxine?

Plain description, key identifiers and synonyms

Chloroxine is a monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. A synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp. It has a role as an antibacterial agent, an antiseborrheic and an antifungal drug. It is an organochlorine compound and a monohydroxyquinoline. It is functionally related to a quinolin-8-ol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5,7-dichloroquinolin-8-ol
CAS number
773-76-2 CAS number cross-checked
EC number
212-258-3
Molecular formula
C9H5Cl2NO
UNII
2I8BD50I8B
MDL number
MFCD00006786
InChIKey
WDFKMLRRRCGAKS-UHFFFAOYSA-N
InChI
InChI=1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
SMILES (canonical and isomeric)
C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1

Synonyms

  • 5,7-Dichloroquinolin-8-ol
  • 5,7-Dichloro-8-hydroxyquinoline
  • 5,7-Dichloro-8-quinolinol
  • Chlorquinol
  • Capitrol
  • Quixalin
  • Dichlorohydroxyquinoline
  • 5,7-Dichlorooxine
  • 5,7-Dichloroxine
  • 8-Quinolinol, 5,7-dichloro-
  • 5,7-Dichloro-8-oxyquinoline
  • 5,7-Dichlor-8-hydroxychinolin
  • dichloroquine
  • Dichloroxin
  • Chloroxyquinoline
  • Dichloroquinolinol
  • Clofuzid
  • Endiaron
  • Chlofucid
  • Dikhloroskin
  • Quesyl
  • Chlorohydroxyquinoline
  • CHQ
  • 5,7-Dichloro-8-hydroquinoline
  • Chloroxine (USAN)
Show all 33 synonyms
  • Clioquinol EP Impurity B
  • Capitrol Cream Shampoo
  • 5,7-Dichloro-8-oxine
  • SQ 16401
  • 5,7-Dichloroquinolin-8-ol, Clioquinol Imp. B (EP), Clioquinol Impurity B
  • Capitrol (TN)
  • Clioquinol Impurity 6
  • 8-Quinolinol,7-dichloro-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
214.05 g/molcalc.
Exact mass
212.9748 Dacalc.
LogP (octanol/water)
3.25calc.
Topological polar surface area
33.12 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
13calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2ncccc2c1

c1ccc2ncccc2c1

2 rings, 10 atoms, the Quinoline ring system.

21,766 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Chloroxine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 15 suppliers
15 of 15 offers
  • China ManufacturerUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
    Price on request
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  • China, KowloonUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • United States, HauppaugeUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • China, ChongqingUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • China, HangzhouUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • United States, Wood DaleUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • China, ShanghaiUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • Ukraine, KievUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • China, Hong KongUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
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  • Canada, Niagara-on-the-LakeUnclaimed profile
    ChloroxineGrade, purity and minimum order on request
    Price on request
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

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Chloroxine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Bacterial Agents
  • Antifungal Agents

Roles

  • antibacterial agent
  • antifungal agent
  • antifungal drug
  • antiinfective agent
  • antimicrobial agent
  • antiseborrheic
  • dermatologic drug
  • pharmaceutical

Pharmacology

Chloroxine is a synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epidermis, thereby reducing excessive scaling associated with dandruff or seborrheic dermatitis of the scalp, including psoriasis and eczema.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Chloroxine is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whetherโ€ฆ

World exports in 2024
$939M
โˆ’14.6% vs 2023, imports $1.48B
2019 to 2024
Top exporters
  1. China30.1%
  2. India * partner reported16.7%
  3. Switzerland * partner reported14.1%
Top importers
  1. United Kingdom19.2%
  2. Germany16.0%
  3. Romania8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Chloroxine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Chloroxine, based on the data on this page

What is Chloroxine?

Chloroxine is a monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. A synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp.

What is the CAS number of Chloroxine?

The CAS registry number of Chloroxine is 773-76-2.

What is the molecular formula and weight of Chloroxine?

The molecular formula of Chloroxine is C9H5Cl2NO and its molar mass is 214.05 g/mol.

What is Chloroxine used for?

Known uses and roles of Chloroxine include antibacterials and antibiotics in pharmaceuticals, antifungals in pharmaceuticals, antibacterial agent, antifungal agent, antifungal drug and 7 more.

Is Chloroxine hazardous?

Chloroxine carries the GHS signal word "Danger". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Chloroxine?

Chloroxine is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whetherโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Chloroxine?

CompoundList lists 15 suppliers of Chloroxine in China, United States, Canada, Czech Republic and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Chloroxine?

Suppliers quote Chloroxine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Chloroxine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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