Clindamycin
Also known as Chlolincocin, Clindamicina, Clinimycin
Key facts
What buyers check first
- CAS number
- 18323-44-9
- Formula
- C18H33ClN2O5S
- Molar mass
- 424.99 g/mol
- Appearance
- Yellow, amorphous solid
- HS code
- 294190
- Category
- Antibiotics and anti-infectives

What is Clindamycin?
Plain description, key identifiers and synonyms
Clindamycin is a semisynthetic broad spectrum antibiotic produced by chemical modification of the parent compound lincomycin. Clindamycin dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. (NCI04)
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
- CAS number
- 18323-44-9 CAS number cross-checked
- EC number
- 242-209-1
- Molecular formula
- C18H33ClN2O5S
- UNII
- 3U02EL437C
- MDL number
- MFCD00072005
- InChIKey
- KDLRVYVGXIQJDK-AWPVFWJPSA-N
- InChI
- InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1
- Canonical SMILES
- CCCC1CC(C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O)N(C)C1
- Isomeric SMILES
- CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl
Synonyms
- Chlolincocin
- Clindamicina
- Clinimycin
- Clindamycine
- 7-Chlorolincomycin
- 7(S)-Chloro-7-deoxylincomycin
- Clindamycinum
- 7-Chloro-7-deoxylincomycin
- 7-Deoxy-7(S)-chlorolincomycin
- Clindamycin In 5 Percent Dextrose
- (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
- L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-((((2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-
- L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-
- L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans-alpha-
- Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside
- Chlorlincocin
- (2S,4R)-N-((1S,2S)-2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide
- ClindaMed Oral Drops
- clindamycini hydrochloridum
- 7 Chloro 7 deoxylincomycin
- Monohydrochloride, Clindamycin
- Clindamycin in percent Dextrose
- (2S,4R)-N-(2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide
- Monohydrate Clindamycin Monohydrochloride
- Monohydrochloride, Monohydrate Clindamycin
Show all 35 synonymsShow fewer synonyms
- Clindamax
- Dalacine
- Dalacin C
- Sobelin
- Clindamycin (USAN/INN)
- (2S,4R)-N-((1S,2S)-2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide
- Cleocin
- Klimicin
- ClindaDerm
- Klindan 300
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Yellow, amorphous solidexp.Measured value |
|---|
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 424.99 g/molcalc.Computed value |
|---|---|
| Exact mass | 424.1799 Dacalc.Computed value |
| LogP (octanol/water) | 0.39calc.Computed value |
| Topological polar surface area | 102.3 Ųcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 7calc.Computed value |
| Rotatable bonds | 7calc.Computed value |
| Heavy atoms | 27calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.94calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 9calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H317May cause an allergic skin reaction.
- H319Causes serious eye irritation.
- H362May cause harm to breast-fed children.
Precautionary statements (19)
- P203Obtain, read and follow all safety instructions before use.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P263Avoid contact during pregnancy and while nursing.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P318If exposed or concerned, get medical advice.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidClindamycin suppliers
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- India, SecunderabadUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- India, Mumbai ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- India, Patiala ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- Spain, Sant Celoni ManufacturerUnclaimed profileClindamycin phosphate hydrateGrade, purity and minimum order on requestPrice on request
- India, Ahmedabad ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- Switzerland, Manno ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- Bangladesh, Dhaka ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- Jordan, Amman ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- Pakistan, Rawalpindi ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
- Egypt, Cairo ManufacturerUnclaimed profileClindamycinGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
98 suppliers in 24 countries
- United States27
- China17
- India17
- Bangladesh5
- Germany5
- Spain4
- and 18 more countries
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Clindamycin price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Semi-synthetic antibiotic prepared from lincomycin.
Clindamycin has found use in the treatment of common infections caused by gram-positive cocci.
It is used as an orally-active lincomycin-group antibiotic with the same range of activity as lincomycin.
Veterinary medication:.
Use classes: Pharmaceuticals, Animal Drugs.
Industries and functions
Pharmacological actions
- Anti-Bacterial Agents
- Protein Synthesis Inhibitors
Roles
- environmental contaminant
- xenobiotic
Pharmacology
Clindamycin is a Lincosamide Antibacterial. The physiologic effect of clindamycin is by means of Decreased Sebaceous Gland Activity and Neuromuscular Blockade.
How it is made
Lincomycin is treated with a solution of Rydon reagent prepared from triphenylphosphine, acetonitrile, and chlorine. The base is ultimately reacted with hydrochloric acid.
First resulted from the reaction of lincomycin and thionyl chloride, improved synthetic methods involve the reaction of lincomycin and triphenylphosphine dichloride or triphenylphosphine in carbon tetrachloride.
Synthesized ... by introducing a chlorine atom at the 7 position of lincomycin.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Clindamycin is traded under.
Antibiotics, other
- China39.7%
- United States11.3%
- Switzerland * partner reported10.9%
* Partner reported figures, a lower bound.
The HS code shown for Clindamycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Clindamycin, based on the data on this page
What is Clindamycin?
What is the CAS number of Clindamycin?
What is the molecular formula and weight of Clindamycin?
What is Clindamycin used for?
Is Clindamycin hazardous?
What is the HS code of Clindamycin?
Where can I buy Clindamycin?
Where can I buy Clindamycin in India?
What is the price of Clindamycin?
Guides for buyers
Practical guides that help when you source, ship or handle Clindamycin
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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