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(-)-Codeine phosphate safety data

GHS hazards, precautions, first aid, handling and transport for (-)-Codeine phosphate. A classification summary, not a safety data sheet.
CAS 52-28-8Formula C18H24NO7P
Controlled or monitored substance

(-)-Codeine phosphate is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

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GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

GHS classification

Pictograms, signal word and hazard classes of the GHS classification

GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
Signal word
Danger

Hazard classes and categories

  • Acute Tox. 3 (oral)
  • Skin Sens. 1
  • Resp. Sens. 1
  • Repr. 1A/1B
  • Repr. 2

Hazard statements

H codes grouped by type. Percentages show the share of classification notifications that report the statement

Health hazards

  • H301Toxic if swallowed.
  • H317May cause an allergic skin reaction.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H360May damage fertility or the unborn child.
  • H361Suspected of damaging fertility or the unborn child.

Precautionary statements

P codes for prevention, response, storage and disposal

Prevention

  • P203Obtain, read and follow all safety instructions before use.
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.

Response

  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.

Storage

  • P403Store in a well-ventilated place.
  • P405Store locked up.

Disposal

  • P501Dispose of contents and container in accordance with local regulations.

First aid

General first aid measures. Get medical advice if you feel unwell

If inhaled
IMMEDIATELY leave the contaminated area, take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used, if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
Skin contact
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
Eye contact
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
If swallowed
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

Handling, storage and disposal

Summaries only, follow the supplier SDS for your grade

Safe handling

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.

Exposure limits and toxicity

Occupational exposure limits and toxicity data

SYMPTOMS: Symptoms of exposure to this compound include dryness of the mouth, nose and throat, urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, hypotension, headache, palpitations, tachycardia, extrasystoles, hemolytic anemia, thrombocytopenia, agranulocytosis, sedation, sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, tremor, irritability, excitation, anxiety, nervousness, insomnia euphoria, paresthesias, blurred vision, diplopia, acute labyrinthitis, tinnitus, hysteria, neuritis, convulsions, central nervous system depression, hallucinations, epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation…

Supplier safety data sheets

SDS documents uploaded by suppliers who list this chemical

No supplier has uploaded an SDS for (-)-Codeine phosphate yet.

Safety questions

Quick answers about handling (-)-Codeine phosphate safely

Is (-)-Codeine phosphate hazardous?

(-)-Codeine phosphate carries the GHS signal word "Danger". Main hazards: toxic if swallowed, may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

Which GHS pictograms apply to (-)-Codeine phosphate?

The GHS classification of (-)-Codeine phosphate shows 3 pictograms: GHS06 (acute toxicity (severe)), GHS07 (harmful or irritant), GHS08 (serious health hazard).

Where can I get the SDS for (-)-Codeine phosphate?

Ask the supplier for the safety data sheet of the exact grade you buy. Suppliers on CompoundList can attach their SDS to listings and send it with a quote. This page is a GHS classification summary, not an SDS.

GHS classification summary, not an SDS. Always check the supplier's SDS. Last updated 7 Oct 2026. Report an error