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Steroids and sterols

Convallatoxin

Also known as Corglycone, Convallaton, Corglykon

CAS 508-75-8Formula C29H42O10Molar mass 550.65 g/molEC 208-086-3
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 3 suppliers listed
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Convallatoxin chemical structure, C29H42O10, CAS 508-75-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Prisms from methanol + ether
Melting point
235 to 242
Solubility
Slightly soluble in water
HS code
293890
Category
Steroids and sterols
Illustrative photo, closed blue fibre drums on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Convallatoxin?

Plain description, key identifiers and synonyms

Convallatoxin is a cardenolide glycoside that consists of strophanthidin having a 6-deoxy-alpha-L-mannopyranosyl (L-rhamnosyl) group attached at position 3. It has a role as a metabolite and a vasodilator agent. It is a steroid aldehyde, a steroid lactone, an alpha-L-rhamnoside, a 14beta-hydroxy steroid, a 19-oxo steroid and a 5beta-hydroxy steroid. It is functionally related to a strophanthidin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
CAS number
508-75-8 CAS number cross-checked
EC number
208-086-3
Molecular formula
C29H42O10
UNII
JY264VIR1Y
MDL number
MFCD00069477
InChIKey
HULMNSIAKWANQO-JQKSAQOKSA-N
InChI
InChI=1S/C29H42O10/c1-15-22(32)23(33)24(34)25(38-15)39-17-3-8-27(14-30)19-4-7-26(2)18(16-11-21(31)37-13-16)6-10-29(26,36)20(19)5-9-28(27,35)12-17/h11,14-15,17-20,22-25,32-36H,3-10,12-13H2,1-2H3/t15-,17-,18+,19-,20+,22-,23+,24+,25-,26+,27-,28-,29-/m0/s1
Canonical SMILES
CC1OC(OC2CCC3(C=O)C4CCC5(C)C(C6=CC(=O)OC6)CCC5(O)C4CCC3(O)C2)C(O)C(O)C1O
Isomeric SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2CC[C@@]3([C@H]4CC[C@@]5([C@H](CC[C@@]5([C@@H]4CC[C@@]3(C2)O)O)C6=CC(=O)OC6)C)C=O)O)O)O

Synonyms

  • Corglycone
  • Convallaton
  • Corglykon
  • Korglykon
  • Convallotoxin
  • Convallaotoxin
  • Corglycon
  • Convallatoxoside
  • Strophanthidin 3-O-alpha-L-rhamnoside
  • Strophanthidin, 3-(6-deoxy-alpha-L-mannopyranoside)
  • Strophanthidin alpha-L-rhamnoside
  • Rhamnoside, strophanthidin-3, alpha-L-
  • 3beta-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide
  • 3beta-(6-deoxy-alpha-L-mannopyranosyloxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide
  • Mannopyranoside, strophanthidin-3,6-deoxy-, alpha-L-
  • Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)-
  • korglycon
  • (3beta,5beta)-3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-card-20(22)-enolide
  • strophanthidin-alpha-L-rhamnoside
  • 5beta,14beta-Dihydroxy-19-oxo-3beta((alpha-L-rhamnopyranosyl)oxy)card-20,22-enolide
  • 5beta,14beta-Dihydroxy-19-oxo-3beta[(alpha-L-rhamnopyranosyl)oxy]card-20,22-enolide
  • 3beta-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide
  • Convallatoxin (Standard)
  • Convallatoxin, >=65%
  • 3beta-(alpha-L-rhamnopyranosyloxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide
Show all 28 synonyms
  • Card-20(22)-enolide, 3-[(6-deoxyhexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-
  • Card-20(22)-enolide, 3-((6-deoxy-alpha-l-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5.beta.)-
  • Convallatoxin, Convallotoxin, Corglycone, Strophanthidin 3-O-alpha-L-rhamnoside, Strophanthidin, 3-(6-deoxy-alpha-L-mannopyranoside)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Prisms from methanol + etherexp.
Melting point
235 to 242exp.
Solubility
Slightly soluble in waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
550.65 g/molcalc.
Exact mass
550.2778 Dacalc.
LogP (octanol/water)
0.75calc.
Topological polar surface area
163 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
10calc.
Rotatable bonds
4calc.
Heavy atoms
39calc.
Rings
6calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.86calc.
Formal charge
0calc.
Stereocentres
13calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C(C2CCC3C2CCC2C4CCC(OC5CCCCO5)CC4CCC23)CO1

O=C1C=C(C2CCC3C2CCC2C4CCC(OC5CCCCO5)CC4CCC23)CO1

6 rings, 30 atoms.

167 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301 + H311 + H331Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled.
  • H301Toxic if swallowed.
  • H311Toxic in contact with skin.
  • H331Toxic if inhaled.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Convallatoxin suppliers

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All 3 suppliers

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Where suppliers are based

3 suppliers in 1 country

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Convallatoxin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Vasodilator Agents

Roles

  • cardiovascular drug
  • metabolite
  • pharmaceutical
  • vasodilator agent

How it is made

Synthesis from strophanthidin and acetobromrhamnose: Reyle et al., Helv Chim Acta 33, 1541 (1950), Haede et al., German patent 1933090 (1971 to Hoechst).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Convallatoxin, Ref no: 105, Annex ref: II/105

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Convallatoxin is traded under.

HS 2938.90Indicative HS code

Natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives

World exports in 2024
$1.4B
−8.3% vs 2023, imports $1.35B
2019 to 2024
Top exporters
  1. China49.2%
  2. France * partner reported8.9%
  3. Malaysia6.1%
Top importers
  1. United States22.3%
  2. India * partner reported7.8%
  3. Brazil5.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Convallatoxin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Convallatoxin, based on the data on this page

What is Convallatoxin?

Convallatoxin is a cardenolide glycoside that consists of strophanthidin having a 6-deoxy-alpha-L-mannopyranosyl (L-rhamnosyl) group attached at position 3. It has a role as a metabolite and a vasodilator agent.

What is the CAS number of Convallatoxin?

The CAS registry number of Convallatoxin is 508-75-8.

What is the molecular formula and weight of Convallatoxin?

The molecular formula of Convallatoxin is C29H42O10 and its molar mass is 550.65 g/mol.

What is Convallatoxin used for?

Known uses and roles of Convallatoxin include cardiovascular drug, metabolite, pharmaceutical, vasodilator agent and vasodilator agents.

Is Convallatoxin hazardous?

Convallatoxin carries the GHS signal word "Danger". Main hazards: toxic if swallowed. toxic in contact with skin. toxic if inhaled, toxic if swallowed, toxic in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Convallatoxin?

Convallatoxin is usually classified under HS code 293890 (Glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Convallatoxin?

CompoundList lists 3 suppliers of Convallatoxin in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Convallatoxin?

Suppliers quote Convallatoxin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Convallatoxin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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