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Other active pharmaceutical ingredients

Cyclopentolate

Also known as Ciclopentolato, 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate, Cyclopentolatum

CAS 512-15-2Formula C17H25NO3Molar mass 291.39 g/molEC 208-136-4
GHS signal word: Warning. Pictograms: Harmful or irritant 47 suppliers listed Drug substance
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Cyclopentolate chemical structure, C17H25NO3, CAS 512-15-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
512-15-2
Formula
C17H25NO3
Molar mass
291.39 g/mol
EC number
208-136-4
HS code
292219
Category
Other active pharmaceutical ingredients

What is Cyclopentolate?

Plain description, key identifiers and synonyms

Cyclopentolate is a carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action. It has a role as a diagnostic agent, a muscarinic antagonist, a parasympatholytic and a mydriatic agent. It is a tertiary alcohol, a carboxylic ester and a tertiary amino compound. It is functionally related to a N,N-dimethylethanolamine and a (1-hydroxycyclopentyl)phenylacetic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate
CAS number
512-15-2 CAS number cross-checked
EC number
208-136-4
Molecular formula
C17H25NO3
UNII
I76F4SHP7J
MDL number
MFCD00599448
InChIKey
SKYSRIRYMSLOIN-UHFFFAOYSA-N
InChI
InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3
SMILES (canonical and isomeric)
CN(C)CCOC(=O)C(C1=CC=CC=C1)C2(CCCC2)O

Synonyms

  • Ciclopentolato
  • 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate
  • Cyclopentolatum
  • Bell Pentolate
  • (+-)-cyclopentolate
  • 2-(Dimethylamino)ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate
  • 1-hydroxy-alpha-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester
  • alpha-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester
  • beta-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate
  • beta-(Dimethylamino)ethyl (1-hydroxycyclopentyl)phenylacetate
  • 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid beta-(dimethylamino)ethyl ester
  • Benzeneacetic acid, alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl ester
  • Cyclopentylate
  • Cyclopentolate (INN)
  • 2-(Dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate
  • Tsiklopentolat, Cyclogyl, DL-Cyclopentolate
  • Cyclopentoiate
  • Diopentolate
  • Bell Pentolate (TN)
  • cyclo-pentolatum
  • Cyclogyl (Salt/Mix)
  • Mydrilate (Salt/Mix)
  • (+/-)-cyclopentolate
  • 2-Dimethylaminoethyl 2-(1-hydroxycyclopentyl)-2-phenylacetat
  • DivK1c_000610
Show all 26 synonyms
  • 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenyl-acetate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
291.39 g/molcalc.
Exact mass
291.1834 Dacalc.
LogP (octanol/water)
2.18calc.
Topological polar surface area
49.77 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
21calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.59calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CC2CCCC2)cc1

c1ccc(CC2CCCC2)cc1

2 rings, 12 atoms, the Benzene, (cyclopentylmethyl)- ring system.

468 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
Precautionary statements (13)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cyclopentolate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 47 suppliers
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Where suppliers are based

47 suppliers in 13 countries

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Cyclopentolate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Muscarinic Antagonists
  • Mydriatics
  • Parasympatholytics

Roles

  • cholinergic antagonist
  • cholinergic drug
  • diagnostic agent
  • muscarinic antagonist
  • mydriatic agent
  • neurotransmitter agent
  • ophthalmology drug
  • parasympatholytic
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cyclopentolate is traded under.

HS 2922.19Indicative HS code

Amino-alcohols, other than those containing more than one kind of oxygen function, their…

World exports in 2024
$2.2B
−4.7% vs 2023, imports $2.27B
2019 to 2024
Top exporters
  1. China21.7%
  2. Germany17.3%
  3. United States15.6%
Top importers
  1. India * partner reported11.0%
  2. United States9.0%
  3. Germany7.2%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cyclopentolate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cyclopentolate, based on the data on this page

What is Cyclopentolate?

Cyclopentolate is a carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine.

What is the CAS number of Cyclopentolate?

The CAS registry number of Cyclopentolate is 512-15-2.

What is the molecular formula and weight of Cyclopentolate?

The molecular formula of Cyclopentolate is C17H25NO3 and its molar mass is 291.39 g/mol.

What is Cyclopentolate used for?

Use classes: Pharmaceuticals.

Is Cyclopentolate hazardous?

Cyclopentolate carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful in contact with skin, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cyclopentolate?

Cyclopentolate is usually classified under HS code 292219 (Amino-alcohols, other than those containing more than one kind of oxygen function, their…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cyclopentolate?

CompoundList lists 47 suppliers of Cyclopentolate in China, United States, United Kingdom, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Cyclopentolate in India?

2 suppliers in India list Cyclopentolate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Cyclopentolate?

Suppliers quote Cyclopentolate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cyclopentolate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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