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Impurities and reference standards

Cytidine

Also known as Cytosine riboside, 4-Amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone, 1-beta-D-Ribofuranosylcytosine

CAS 65-46-3Formula C9H13N3O5Molar mass 243.22 g/molEC 200-610-9
GHS signal word: Warning. Pictograms: Harmful or irritant 112 suppliers listed
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Cytidine chemical structure, C9H13N3O5, CAS 65-46-3
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Powder
Melting point
215 to 216.1
Solubility
Greater than or equal to 100 mg/mL at 63 °F
HS code
293499
Category
Impurities and reference standards
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Cytidine?

Plain description, key identifiers and synonyms

Cytidine is a pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N1-glycosidic bond. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is functionally related to a cytosine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
CAS number
65-46-3 CAS number cross-checked
EC number
200-610-9
Molecular formula
C9H13N3O5
UNII
5CSZ8459RP
MDL number
MFCD00006545
INCI name
CYTIDINE
InChIKey
UHDGCWIWMRVCDJ-XVFCMESISA-N
InChI
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1
Canonical SMILES
Nc1ccn(C2OC(CO)C(O)C2O)c(=O)n1
Isomeric SMILES
C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

Synonyms

  • Cytosine riboside
  • 4-Amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone
  • 1-beta-D-Ribofuranosylcytosine
  • beta-D-Ribofuranoside, cytosine-1
  • 1beta-D-Ribofuranosylcytosine
  • 4-Amino-1beta-D-ribofuranosyl-2(1H)-pyrimidinone
  • 2(1H)-Pyrimidinone, 4-amino-1-beta-D-ribofuranosyl-
  • 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 4-amino-1-beta-D-ribofuranosylpyrimidin-2(1H)-one
  • 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
  • Riboside, Cytosine
  • Cytosine Ribonucleoside
  • Ribonucleoside, Cytosine
  • 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one
  • 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2-dihydropyrimidin-2-one
  • 1beta-Ribofuranosylcytosine
  • 1-beta-Ribofuranosylcytosine
  • Cytidin
  • Cytosine, 1-beta-D-ribofuranosyl-
  • 1beta-2'-Ribofuranosylcytosine, d-
  • Cyd
  • 2(1H)-Pyrimidinone, 4-amino-1beta-D-ribofuranosyl-
  • cytosine-1beta-D-Ribofuranoside
  • 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
  • 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
Show all 34 synonyms
  • Cytidine, Cytarabine Impurity E
  • Zytidin
  • beta-cytidine
  • 3h-cytidine
  • Posilent (TN)
  • CTN
  • beta-D-Ribo-C
  • Cytidine, 99%
  • 4-Amino-1-|A-D-ribofuranosyl-2(1H)-pyrimidinone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Powderexp.
Melting point
215 to 216.1exp.
Solubility
Greater than or equal to 100 mg/mL at 63 °Fexp.
Vapour pressure
Negligibleexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
243.22 g/molcalc.
Exact mass
243.0855 Dacalc.
LogP (octanol/water)
-2.56calc.
Topological polar surface area
130.8 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
2calc.
Heavy atoms
17calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.56calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1ncccn1C1CCCO1

O=c1ncccn1C1CCCO1

2 rings, 12 atoms.

1,589 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cytidine suppliers

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All 112 suppliers
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Where suppliers are based

112 suppliers in 17 countries

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Cytidine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name CYTIDINE(skin conditioning, skin protecting)

Roles

  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • animal metabolite
  • antineoplastic agent
  • antipsychotic agent
  • bacterial metabolite
  • central nervous system depressant
  • central nervous system drug
  • eukaryotic metabolite
  • fungal metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • ophthalmology drug
  • pharmaceutical
  • prokaryotic metabolite
  • psychotropic drug
  • tranquilizing drug

Functional uses

  • Humectant
  • Softener and conditioner

Cosmetic functions

  • Skin conditioning
  • Skin protecting

Pharmacology

Cytidine is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cytidine is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Cytidine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cytidine, based on the data on this page

What is Cytidine?

Cytidine is a pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N1-glycosidic bond. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is functionally related to a cytosine.

What is the CAS number of Cytidine?

The CAS registry number of Cytidine is 65-46-3.

What is the molecular formula and weight of Cytidine?

The molecular formula of Cytidine is C9H13N3O5 and its molar mass is 243.22 g/mol.

What is Cytidine used for?

Known uses and roles of Cytidine include skin conditioning agents in cosmetics and personal care, escherichia coli metabolite, saccharomyces cerevisiae metabolite, animal metabolite, antineoplastic agent and 19 more.

Is Cytidine hazardous?

Cytidine carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cytidine?

Cytidine is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cytidine?

CompoundList lists 112 suppliers of Cytidine in China, United States, Germany, Spain and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Cytidine in India?

3 suppliers in India list Cytidine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Cytidine?

Suppliers quote Cytidine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cytidine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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