Dactinomycin safety data

GHS hazards, precautions, first aid, handling and transport for Dactinomycin. A classification summary, not a safety data sheet.

CAS 50-76-0Formula C₆₂H₈₆N₁₂O₁₆

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

GHS classification

Pictograms, signal word and hazard classes of the GHS classification

Acute toxicity (severe)

Serious health hazard

Signal word

Danger

Hazard classes and categories

Acute Tox. 1/2 (oral)
Carc. 1A/1B
Repr. 1A/1B

Hazard statements

H codes grouped by type. Percentages show the share of classification notifications that report the statement

Health hazards

H300Fatal if swallowed.
H350May cause cancer.
H360May damage fertility or the unborn child.

Precautionary statements

P codes for prevention, response, storage and disposal

Prevention

P203Obtain, read and follow all safety instructions before use.
P264Wash skin thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves, protective clothing, eye protection and face protection.

Response

P301 + P316If swallowed: Get emergency medical help immediately.
P318If exposed or concerned, get medical advice.
P321Specific treatment (see supplemental first aid instructions on the label).
P330Rinse mouth.

Storage

P405Store locked up.

Disposal

P501Dispose of contents and container in accordance with local regulations.

First aid

General first aid measures. Get medical advice if you feel unwell

If inhaled

IMMEDIATELY leave the contaminated area, take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used, if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

Skin contact

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

Eye contact

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

If swallowed

If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Generally, the induction of vomiting is NOT recommended outside of a physician's care due to the risk of aspirating the chemical into the victim's lungs. However, if the victim is conscious and not convulsing and if medical help is not readily available, consider the risk of inducing vomiting because of the high toxicity of the chemical ingested. Ipecac syrup or salt water may be used in such an emergency. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure th…

Handling, storage and disposal

Summaries only, follow the supplier SDS for your grade

Safe handling

/PRECAUTIONS FOR ANTINEOPLASTIC AGENTS:/ Protective apparel: Disposable closed-front gown or coveralls, disposable utility gloves over disposable latex gloves, NIOSH-approved air-purifying half-mask respirator equipped with a high efficiency filter, and eye protection should be worn. /Antineoplastic agents/ /PRECAUTIONS FOR ANTINEOPLASTIC AGENTS:/ Class 100 clean-air work stations, both horizontal and vertical airflow (with no containment characteristics), are inappropriate engineering controls for handling hazardous drugs because they provide no personnel protection and permit environmental contamination. Although there are no engineering controls designed specifically for the safe handling of hazardous chemicals as sterile products, Class II contained vertical-flow biological safety cabinets (biohazard cabinets) have been adopted for this use.

Storage

Store at 25 °C (77deg F), excursions permitted to 15-30 °C (59-86 °F). Protect from light and humidity.

Disposal

SRP: Expired or waste pharmaceuticals shall carefully take into consideration applicable DEA, EPA, and FDA regulations. It is not appropriate to dispose by flushing the pharmaceutical down the toilet or discarding to trash. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator. /PRECAUTIONS FOR ANTINEOPLASTIC AGENTS:/ All contaminated disposables should be contained in sealable bags for transfer to larger waste containers. /Antineoplastic agents/

Exposure limits and toxicity

Occupational exposure limits and toxicity data

SYMPTOMS: Symptoms of exposure to this chemical may include nausea, vomiting, malaise, fatigue, lethargy, fever, myalgia, proctitis, hypocalcemia, cheilitis, dysphagia, esophagitis, ulcerative stomatitis, pharyngitis, anorexia, abdominal pain, diarrhea, gastrointestinal ulceration, anemia, agranulocytosis, leukopenia, thrombopenia, pancytopenia, reticulopenia, alopecia, skin eruptions, acne, flare-up of erythema or increased pigmentation of previously irradiated skin. It is corrosive to soft tissues. Other symptoms include temporary loss of scalp hair and eyebrows. ACUTE/CHRONIC HAZARDS: This compound may be fatal if inhaled, swallowed or absorbed through the skin.

Transport information

UN dangerous goods classification for road, sea and air

UN number: UN 2811

Shipping rules depend on mode, quantity and packaging. Confirm the classification with the supplier SDS and your freight forwarder.

Supplier safety data sheets

SDS documents uploaded by suppliers who list this chemical

No supplier has uploaded an SDS for Dactinomycin yet. Suppliers usually send one with their quote. Request quotes

Safety questions

Quick answers about handling Dactinomycin safely

Is Dactinomycin hazardous?

Dactinomycin carries the GHS signal word "Danger". Main hazards: fatal if swallowed, may cause cancer, may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

Which GHS pictograms apply to Dactinomycin?

The GHS classification of Dactinomycin shows 2 pictograms: GHS06 (acute toxicity (severe)), GHS08 (serious health hazard).

What is the UN number of Dactinomycin?

Dactinomycin is transported under UN 2811. Check the supplier SDS and the current ADR, IMDG or IATA rules before shipping.

How should Dactinomycin be stored?

Store at 25 °C (77deg F), excursions permitted to 15-30 °C (59-86 °F). Protect from light and humidity.

Where can I get the SDS for Dactinomycin?

Ask the supplier for the safety data sheet of the exact grade you buy. Suppliers on CompoundList can attach their SDS to listings and send it with a quote. This page is a GHS classification summary, not an SDS.

GHS classification summary, not an SDS. Always check the supplier's SDS. Last updated 7 Oct 2026. Report an error

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