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Vitamins, minerals and nutrients

Dexpanthenol

Also known as D-Panthenol, Pantothenol, Bepanthen

CAS 81-13-0Formula C9H19NO4Molar mass 205.25 g/molEC 201-327-3
151 suppliers listed Drug substance
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Dexpanthenol chemical structure, C9H19NO4, CAS 81-13-0
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Hygroscopic oil
Boiling point
118 to 120
Density
1.2 at 20 °C/20 °C
Solubility
Freely soluble in methanol, water, alcohol, slightly soluble in ether
HS code
293624
Category
Vitamins, minerals and nutrients
Illustrative photo, a closed 1000 litre IBC tote in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Dexpanthenol?

Plain description, key identifiers and synonyms

Pantothenol is a monocarboxylic acid amide that is 3,3-dimethylbutanamide substituted by hydroxy groups at positions 2 and 4 and a 3-hydroxypropyl group at the carbomyl nitrogen. It has a role as a cholinergic drug and a provitamin. It is an amino alcohol and a monocarboxylic acid amide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
CAS number
81-13-0 CAS number cross-checked
EC number
201-327-3
Molecular formula
C9H19NO4
UNII
1O6C93RI7Z
MDL number
MFCD00065006
INCI name
PANTHENOL
InChIKey
SNPLKNRPJHDVJA-ZETCQYMHSA-N
InChI
InChI=1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1
Canonical SMILES
CC(C)(CO)C(O)C(=O)NCCCO
Isomeric SMILES
CC(C)(CO)[C@H](C(=O)NCCCO)O

Synonyms

  • D-Panthenol
  • Pantothenol
  • Bepanthen
  • D-Pantothenyl alcohol
  • Ilopan
  • Pantol
  • (+)-Panthenol
  • Bepanthene
  • Bepantol
  • Motilyn
  • Panadon
  • Thenalton
  • d-Pantothenol
  • Pantothenyl alcohol
  • Panthoderm
  • Cozyme
  • Zentinic
  • Provitamin B
  • D(+)-Panthenol
  • Pantenyl
  • Synapan
  • D-P-A Injection
  • Intrapan
  • Urupan
  • Pantothenylol
Show all 39 synonyms
  • Dexpantenol
  • D(+)-Pantothenyl alcohol
  • D-Panthenol 50
  • (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
  • Provitamin B5
  • Alcopan-250
  • (R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
  • Dexpanthenolum
  • Penthenol
  • Propanolamine, N-pantoyl-
  • N-Pantoyl-propanolamine
  • Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-
  • Panthenol, (+)-
  • D-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Hygroscopic oilexp.
Taste
Slightly bitter tasteexp.
Boiling point
118 to 120exp.
Density
1.2 at 20 °C/20 °Cexp.
Solubility
Freely soluble in methanol, water, alcohol, slightly soluble in etherexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
205.25 g/molcalc.
Exact mass
205.1314 Dacalc.
LogP (octanol/water)
-1.14calc.
Topological polar surface area
89.79 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
14calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.89calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dexpanthenol suppliers

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All 151 suppliers
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Where suppliers are based

151 suppliers in 26 countries

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Dexpanthenol price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Nutrient.

Biochemical research, food additive and dietary supplement.

Therapeutic category: Cholinergic, dl-form as vitamin.

Use classes: Skin Conditioning Agents, Safer Chemical Classes, Cosmetics.

Cosmetic ingredient, INCI name PANTHENOL(antistatic, hair conditioning, skin conditioning)

Roles

  • anti-inflammatory agent
  • anti-ulcer drug
  • cholinergic drug
  • neurotransmitter agent
  • ophthalmology drug
  • pharmaceutical
  • provitamin

Functional uses

  • Emulsifier
  • Flavouring and nutrient
  • Softener and conditioner

Cosmetic functions

  • Antistatic
  • Hair conditioning
  • Skin conditioning

Pharmacology

Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

How it is made

Prepared by the addition of propanolamine to optically active alpha,gamma-dihydroxy-beta,beta-dimethylbutyrolactone.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • Safer Choice ingredient list (USA)
  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dexpanthenol is traded under.

HS 2936.24Indicative HS code

D- or DL-Pantothenic acid (vitamin B5) and its derivatives

World exports in 2024
$267M
−34.0% vs 2023, imports $338M
2019 to 2024
Top exporters
  1. China67.8%
  2. Netherlands14.7%
  3. Singapore4.4%
Top importers
  1. United States14.7%
  2. Netherlands9.8%
  3. Germany6.3%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Dexpanthenol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dexpanthenol, based on the data on this page

What is Dexpanthenol?

Pantothenol is a monocarboxylic acid amide that is 3,3-dimethylbutanamide substituted by hydroxy groups at positions 2 and 4 and a 3-hydroxypropyl group at the carbomyl nitrogen. It has a role as a cholinergic drug and a provitamin. It is an amino alcohol and a monocarboxylic acid amide.

What is the CAS number of Dexpanthenol?

The CAS registry number of Dexpanthenol is 81-13-0.

What is the molecular formula and weight of Dexpanthenol?

The molecular formula of Dexpanthenol is C9H19NO4 and its molar mass is 205.25 g/mol.

What is Dexpanthenol used for?

Nutrient. Biochemical research, food additive and dietary supplement. Therapeutic category: Cholinergic, dl-form as vitamin. Use classes: Skin Conditioning Agents, Safer Chemical Classes, Cosmetics.

Is Dexpanthenol hazardous?

No GHS hazard classification for Dexpanthenol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Dexpanthenol?

Dexpanthenol is usually classified under HS code 293624 (D- or DL-Pantothenic acid (vitamin B5) and its derivatives). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dexpanthenol?

CompoundList lists 151 suppliers of Dexpanthenol in China, United States, India, Germany and 22 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Dexpanthenol in India?

17 suppliers in India list Dexpanthenol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Dexpanthenol?

Suppliers quote Dexpanthenol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dexpanthenol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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