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Analgesics and anti-inflammatories

Dilmapimod

Also known as 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Pyrido(2,3-d)pyrimidin-7(8H)-one, 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-

CAS 444606-18-2Formula C23H19F3N4O3Molar mass 456.42 g/mol
1 supplier listed
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Dilmapimod chemical structure, C23H19F3N4O3, CAS 444606-18-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
444606-18-2
Formula
C23H19F3N4O3
Molar mass
456.42 g/mol
HS code
293359
Category
Analgesics and anti-inflammatories

What is Dilmapimod?

Plain description, key identifiers and synonyms

Dilmapimod is a chemical substance with the molecular formula C23H19F3N4O3 and a molar mass of 456.42 g/mol. Its CAS registry number is 444606-18-2. The IUPAC name is 8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one
CAS number
444606-18-2
Molecular formula
C23H19F3N4O3
UNII
Q3238VQW0N
MDL number
MFCD16659063
InChIKey
ORVNHOYNEHYKJG-UHFFFAOYSA-N
InChI
InChI=1S/C23H19F3N4O3/c1-12-9-13(24)5-6-15(12)20-16-7-8-19(33)30(21-17(25)3-2-4-18(21)26)22(16)29-23(28-20)27-14(10-31)11-32/h2-9,14,31-32H,10-11H2,1H3,(H,27,28,29)
SMILES (canonical and isomeric)
CC1=C(C=CC(=C1)F)C2=C3C=CC(=O)N(C3=NC(=N2)NC(CO)CO)C4=C(C=CC=C4F)F

Synonyms

  • 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
  • 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one
  • Pyrido(2,3-d)pyrimidin-7(8H)-one, 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-
  • dilmapimodum
  • 8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido(6,5-d)pyrimidin-7-one
  • 8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[6,5-d]pyrimidin-7-one
  • 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)pyrido(2,3-d)pyrimidin-7(8H)-one
  • 8-(2,6-difluorophenyl)-2-((1,3-dihydroxypropan-2-yl)amino)-4-(4-fluoro-2-methylphenyl)-7H,8H-pyrido(2,3-d)pyrimidin-7-one
  • 8-(2,6-difluorophenyl)-2-((1,3-dihydroxypropan-2-yl)amino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7(8H)-one
  • GW 681323
  • SB 681323
  • 8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one
  • GSK 681323
  • SB-681323, GW 681323
  • 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-((2-hydroxy-1- (hydroxymethyl)ethyl)amino)pyrido(2,3-d)pyrimidin-7(8H)-one
  • Pyrido(2,3-d)pyrimidin-7(8H)-one, 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2- ((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-
  • 8-(2,6-Difluorophenyl)-2-[(1,3-dihydroxypropan-2-yl)amino]-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7(8H)-one
  • 444606-18-2 (free base)
  • Dilmapimod (USAN/INN)
  • Dilmapimod (SB-681323)
  • Dilmapimod (SB-681323)?
  • SB-681323, GW-681323
  • 8-(2,6-difluoro-phenyl)-4-(4-fluoro-2-methyl-phenyl)-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one
  • 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methyl-phenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]pyrido[2,3-d]pyrimidin-7-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
456.42 g/molcalc.
Exact mass
456.1409 Dacalc.
LogP (octanol/water)
2.94calc.
Topological polar surface area
100.3 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
6calc.
Heavy atoms
33calc.
Rings
4calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.17calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1ccc2c(-c3ccccc3)ncnc2n1-c1ccccc1

O=c1ccc2c(-c3ccccc3)ncnc2n1-c1ccccc1

4 rings, 23 atoms.

3 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Dilmapimod suppliers

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Where suppliers are based

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Dilmapimod price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antirheumatic drug
  • cardiovascular drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dilmapimod is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Dilmapimod is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dilmapimod, based on the data on this page

What is Dilmapimod?

Dilmapimod is a chemical substance with the molecular formula C23H19F3N4O3 and a molar mass of 456.42 g/mol. Its CAS registry number is 444606-18-2. The IUPAC name is 8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one.

What is the CAS number of Dilmapimod?

The CAS registry number of Dilmapimod is 444606-18-2.

What is the molecular formula and weight of Dilmapimod?

The molecular formula of Dilmapimod is C23H19F3N4O3 and its molar mass is 456.42 g/mol.

What is Dilmapimod used for?

Known uses and roles of Dilmapimod include anti-inflammatories in pharmaceuticals, antirheumatic drug, cardiovascular drug and pharmaceutical.

Is Dilmapimod hazardous?

No GHS hazard classification for Dilmapimod is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Dilmapimod?

Dilmapimod is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dilmapimod?

CompoundList lists 1 supplier of Dilmapimod in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Dilmapimod?

Suppliers quote Dilmapimod on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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