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Screening compounds

Diphacinone

Also known as Diphenadione, Didandin, Diphenacin

CAS 82-66-6Formula C23H16O3Molar mass 340.38 g/molEC 201-434-5
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard Controlled, licensed buyers only
Request as a licensed buyer Safety data
Diphacinone chemical structure, C23H16O3, CAS 82-66-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Yellow crystals
Melting point
141 to 145
Density
Bulk density: 1.87 g/mL
Solubility
In water, 0.3 mg/L, temp not specified
HS code
291439
Category
Screening compounds
UN number
UN 2811

What is Diphacinone?

Plain description, key identifiers and synonyms

Diphenadione is a beta-triketone and a diarylmethane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(2,2-diphenylacetyl)indene-1,3-dione
CAS number
82-66-6 CAS number cross-checked
EC number
201-434-5
Molecular formula
C23H16O3
UNII
54CA01C6JX
MDL number
MFCD00046317
InChIKey
JYGLAHSAISAEAL-UHFFFAOYSA-N
InChI
InChI=1S/C23H16O3/c24-21-17-13-7-8-14-18(17)22(25)20(21)23(26)19(15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14,19-20H
SMILES (canonical and isomeric)
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)C3C(=O)C4=CC=CC=C4C3=O

Synonyms

  • Diphenadione
  • Didandin
  • Diphenacin
  • Diphenandione
  • Promar
  • Diphacin
  • Diphenadion
  • Oragulant
  • Ratindan
  • Didion
  • Dipaxin
  • Solvan
  • Ramik
  • Diphac
  • 2-(Diphenylacetyl)-1H-indene-1,3(2H)-dione
  • Ratindan 1
  • Difenadione
  • 2-(Diphenylacetyl)-1,3-indandione
  • Difenadiona
  • Diphacins
  • Parakakes
  • Kill-Ko Rat Killer
  • Rodent Cake
  • Gold Crest
  • Contrax-D
Show all 38 synonyms
  • Promar PCQ
  • Diphenadionum
  • URI 788
  • 1,3-Indandione, 2-diphenylacetyl-
  • 2-Diphenylacetyl-1,3-diketohydrindene
  • 1,3-Indandione, 2-(diphenylacetyl)-
  • 1H-Indene-1,3(2H)-dione, 2-(diphenylacetyl)-
  • 2-(Diphenylacetyl)indan-1,3-dione
  • Diphenylacetylindandione
  • difenadion
  • diphacine
  • 2-(2,2-diphenylacetyl)-2,3-dihydro-1H-indene-1,3-dione
  • 2-(2,2-diphenylacetyl)indene-1,3-dione

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Yellow crystalsexp.
Odour
Odorlessexp.
Melting point
141 to 145exp.
Density
Bulk density: 1.87 g/mLexp.
Solubility
In water, 0.3 mg/L, temp not specifiedexp.
Vapour pressure
VP: 1.2 × 10⁻⁸ mm Hgexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
340.38 g/molcalc.
Exact mass
340.1099 Dacalc.
LogP (octanol/water)
4.08calc.
Topological polar surface area
51.21 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
26calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.09calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1c2ccccc2C(=O)C1C(=O)C(c1ccccc1)c1ccccc1

O=C1c2ccccc2C(=O)C1C(=O)C(c1ccccc1)c1ccccc1

4 rings, 26 atoms. This chemical is the scaffold itself.

12 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H300Fatal if swallowed.
  • H372Causes damage to organs through prolonged or repeated exposure.
Precautionary statements (9)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2811
Transport hazard class
6.1
Packing group
I

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Diphacinone suppliers

Controlled substance, listings of documented suppliers only, in the documented ranking

Pesticide toxic

Diphacinone is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Diphacinone

Reference: Highly hazardous pesticide, WHO class Ia or Ib

Our policy on controlled substances
No documented supplier lists it yet

Licensed buyers can post a request for Diphacinone with their licence. Our compliance team reviews it before suppliers see it.

Request as a licensed buyer

Diphacinone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Control of mammal pest, particularly commensal rats and mice but also a variety of field rodents (note: commensal rodents are Norway rat, roof rat, and house mouse).

Control of ... prairie dogs (Cynomys spp.), ground squirrels, and other rodents.

Baticide.

Use classes: Pharmaceuticals.

Roles

  • anticoagulant
  • hematologic agent
  • pharmaceutical

Functional uses

  • Biocide

How it is made

Preparation: D.G. Thomas, United States of America patent 2672483 (1954 to Upjohn).

By the condensation of dimethyl phthalate with diphenylacetone in an inert solvent in the presence of sodium methoxide.

Regulatory status

Inventories, regulations and trade controls that list this substance

Pesticide toxic

Diphacinone is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Diphacinone

Reference: Highly hazardous pesticide, WHO class Ia or Ib

Our policy on controlled substances

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 606-038-00-X

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Diphacinone is traded under.

HS 2914.39Indicative HS code

Aromatic ketones without other oxygen function, other

World exports in 2024
$207M
−12.1% vs 2023, imports $191M
2019 to 2024
Top exporters
  1. China61.4%
  2. India * partner reported12.4%
  3. Italy7.6%
Top importers
  1. India * partner reported11.9%
  2. Germany9.9%
  3. United States8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Diphacinone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Diphacinone, based on the data on this page

What is Diphacinone?

Diphenadione is a beta-triketone and a diarylmethane.

What is the CAS number of Diphacinone?

The CAS registry number of Diphacinone is 82-66-6.

What is the molecular formula and weight of Diphacinone?

The molecular formula of Diphacinone is C23H16O3 and its molar mass is 340.38 g/mol.

What is Diphacinone used for?

Control of mammal pest, particularly commensal rats and mice but also a variety of field rodents (note: commensal rodents are Norway rat, roof rat, and house mouse). Control of ... prairie dogs (Cynomys spp.), ground squirrels, and other rodents. Baticide. Use classes: Pharmaceuticals.

Is Diphacinone hazardous?

Diphacinone carries the GHS signal word "Danger". Main hazards: fatal if swallowed, causes damage to organs through prolonged or repeated exposure. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Diphacinone?

Diphacinone is usually classified under HS code 291439 (Aromatic ketones without other oxygen function, other). This is indicative, confirm it with your customs broker before shipping.

Can I buy Diphacinone on CompoundList?

Diphacinone is a controlled substance. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed by our compliance team before suppliers see it.

Guides for buyers

Practical guides that help when you source, ship or handle Diphacinone

Request as a licensed buyer

Upload your licence with the request. Our compliance team reviews it before the documented suppliers see it.
Request as a licensed buyer
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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