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Cardiovascular and metabolic drugs

Disopyramide

Also known as Dicorantil, Lispine, Disopiramida

CAS 3737-09-5Formula C21H29N3OMolar mass 339.48 g/molEC 223-110-2
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 76 suppliers listed Drug substance
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Disopyramide chemical structure, C21H29N3O, CAS 3737-09-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
3737-09-5
Formula
C21H29N3O
Molar mass
339.48 g/mol
EC number
223-110-2
HS code
293339
Category
Cardiovascular and metabolic drugs

What is Disopyramide?

Plain description, key identifiers and synonyms

Disopyramide is a monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug. It has a role as an anti-arrhythmia drug. It is a member of pyridines, a monocarboxylic acid amide and a tertiary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide
CAS number
3737-09-5 CAS number cross-checkedOther or deprecated CAS: 22059-60-5
EC number
223-110-2
Molecular formula
C21H29N3O
UNII
GFO928U8MQ
MDL number
MFCD00057366
InChIKey
UVTNFZQICZKOEM-UHFFFAOYSA-N
InChI
InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
SMILES (canonical and isomeric)
CC(C)N(CCC(C1=CC=CC=C1)(C2=CC=CC=N2)C(=O)N)C(C)C

Synonyms

  • Dicorantil
  • Lispine
  • Disopiramida
  • Isorythm
  • Rythmodan P
  • Disopyramidum
  • Ritmilen
  • Dl-disopyramide
  • Searle-703
  • (rs)-disopyramide
  • gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide
  • alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide
  • 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-
  • 2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-
  • 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
  • alpha-[2-(Diisopropylamino)ethyl]-alpha-phenyl-2-pyridineacetamide
  • Diisopyramide
  • Palpitine
  • Rythmilen
  • 4-(bis(propan-2-yl)amino)-2-phenyl-2-(pyridin-2-yl)butanamide
  • 4-(bis(propan-2-yl)amino)-2-phenyl-2-(pyridin-2-yl)butanimidic acid
  • 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanimidic acid
  • (2RS)-4-Bis(1-methylethyl)amino-2-phenyl-2-(pyridin-2-yl)butanamide
  • Ritmodan
  • Searle 703
Show all 36 synonyms
  • Disopyramide-d5
  • SC 7031
  • alpha-Diisopropylaminoethyl-alpha-phenylpyridine-2-acetamide
  • 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide
  • 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide
  • 4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
  • 2-Pyridineacetamide, alpha-[2-[bis(1-methylethyl)amino]ethyl]-alpha-phenyl-
  • 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide
  • 4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide
  • 4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
  • a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
339.48 g/molcalc.
Exact mass
339.2311 Dacalc.
LogP (octanol/water)
3.36calc.
Topological polar surface area
59.22 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
8calc.
Heavy atoms
25calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.43calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cc2ccccn2)cc1

c1ccc(Cc2ccccn2)cc1

2 rings, 13 atoms, the 2-(Phenylmethyl)pyridine ring system.

671 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Disopyramide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 76 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

76 suppliers in 14 countries

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Disopyramide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Arrhythmia Agents
  • Voltage-Gated Sodium Channel Blockers

Roles

  • anti-arrhythmia drug
  • cardiovascular drug
  • pharmaceutical

Pharmacology

Disopyramide is an Antiarrhythmic.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Disopyramide is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Disopyramide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Disopyramide, based on the data on this page

What is Disopyramide?

Disopyramide is a monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug. It has a role as an anti-arrhythmia drug.

What is the CAS number of Disopyramide?

The CAS registry number of Disopyramide is 3737-09-5. Other or deprecated CAS numbers: 22059-60-5.

What is the molecular formula and weight of Disopyramide?

The molecular formula of Disopyramide is C21H29N3O and its molar mass is 339.48 g/mol.

What is Disopyramide used for?

Use classes: Pharmaceuticals.

Is Disopyramide hazardous?

Disopyramide carries the GHS signal word "Warning". Main hazards: harmful if swallowed, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Disopyramide?

Disopyramide is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Disopyramide?

CompoundList lists 76 suppliers of Disopyramide in United States, China, United Kingdom, Germany and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Disopyramide?

Suppliers quote Disopyramide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Disopyramide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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