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Synthesis reagents

Dithioerythritol

Also known as 1,4-Dithioerythritol, Dithioerythreitol, (2R,3S)-1,4-Dimercaptobutane-2,3-diol

CAS 6892-68-8Formula C4H10O2S2Molar mass 154.26 g/molEC 229-998-8
GHS signal word: Warning. Pictograms: Harmful or irritant 12 suppliers listed
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Dithioerythritol chemical structure, C4H10O2S2, CAS 6892-68-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
6892-68-8
Formula
C4H10O2S2
Molar mass
154.26 g/mol
EC number
229-998-8
HS code
293090
Category
Synthesis reagents

What is Dithioerythritol?

Plain description, key identifiers and synonyms

Dithioerythritol is the meso-diastereomer of 1,4-dimercaptobutane-2,3-diol, a sulfur-containing sugar derived from the monosaccharide erythrose, and an epimer of dithiothreitol. It has a role as a reducing agent.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol
CAS number
6892-68-8 CAS number cross-checked
EC number
229-998-8
Molecular formula
C4H10O2S2
UNII
R4SVL81GQI
MDL number
MFCD00063750
InChIKey
VHJLVAABSRFDPM-ZXZARUISSA-N
InChI
InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+
Canonical SMILES
OC(CS)C(O)CS
Isomeric SMILES
C([C@H]([C@H](CS)O)O)S

Synonyms

  • 1,4-Dithioerythritol
  • Dithioerythreitol
  • (2R,3S)-1,4-Dimercaptobutane-2,3-diol
  • 2,3-Butanediol, 1,4-dimercapto-, (2R,3S)-rel-
  • (2R,3S)-1,4-disulfanylbutane-2,3-diol
  • erythro-1,4-Dimercapto-2,3-butanediol
  • (2R*,3S*)-1,4-dimercapto-2,3-butanediol
  • 2,3-Butanediol, 1,4-dimercapto-, (R*,S*)-
  • GlyTouCan:G15985JF
  • DTE
  • (2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol
  • trans-1,4-Dimercaptobutane-2,3-diol
  • rel-(2R,3S)-1,4-Dimercapto-2,3-butanediol
  • rel-(2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol
  • Cleland's Reagent, DTE
  • DTU
  • 1,4-Dithioerythritol (DTE)
  • Erythritol, 1,4-dithio-
  • 2,3-Dihydroxy-1,4-dithiolbutane
  • (R*,S*)-1,4-Dimercapto-2,3-butanediol
  • (R*,S*)-1,4-Dimercaptobutane-2,3-diol
  • 3-01-00-02359 (Beilstein Handbook Reference)
  • 1,4-Dithioerythritol, 99%
  • 2,3-Dihydroxy-1,4-butanedithiol
  • DTT
Show all 37 synonyms
  • 1,4-Dithioerythritol, >=99.0%
  • Dithioerythreitol, Molecular biology grade
  • 1,4-Dithioerythritol, >=99.0% (RT)
  • 1,4-Dithioerythritol, BioXtra, >=99.0%
  • (2R*,3S*)-1,4-dimercaptobutane-2,3-diol
  • (2R,3S)-rel-1,4-Dimercapto-2,3-butanediol
  • (2S,3R)-1,4-bis(sulfanyl)butane-2,3-diol
  • 2,3-Butanediol, 1,4-dimercapto-, (theta,S)-
  • erythro-1,4,-Dimercapto-2,3-butanediol
  • 1,4-Dithioerythritol, BioUltra, >=99.0% (RT)
  • 1,4-Dithioerythritol, BioReagent, for molecular biology, >=99.0%
  • erythro-2,3-Dihydroxy-1,4-dithiolbutane, erythro-1,4-Dimercapto-2,3-butanediol, DTE

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
154.26 g/molcalc.
Exact mass
154.0122 Dacalc.
LogP (octanol/water)
-0.43calc.
Topological polar surface area
40.46 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
8calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dithioerythritol suppliers

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All 12 suppliers
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Where suppliers are based

12 suppliers in 6 countries

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Dithioerythritol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Sulfhydryl Reagents

Roles

  • reducing agent

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dithioerythritol is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Dithioerythritol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dithioerythritol, based on the data on this page

What is Dithioerythritol?

Dithioerythritol is the meso-diastereomer of 1,4-dimercaptobutane-2,3-diol, a sulfur-containing sugar derived from the monosaccharide erythrose, and an epimer of dithiothreitol. It has a role as a reducing agent.

What is the CAS number of Dithioerythritol?

The CAS registry number of Dithioerythritol is 6892-68-8.

What is the molecular formula and weight of Dithioerythritol?

The molecular formula of Dithioerythritol is C4H10O2S2 and its molar mass is 154.26 g/mol.

What is Dithioerythritol used for?

Known uses and roles of Dithioerythritol include synthesis reagents in research and laboratory, reducing agent and sulfhydryl reagents.

Is Dithioerythritol hazardous?

Dithioerythritol carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Dithioerythritol?

Dithioerythritol is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dithioerythritol?

CompoundList lists 12 suppliers of Dithioerythritol in United States, China, Canada, Germany and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Dithioerythritol in India?

1 supplier in India list Dithioerythritol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Dithioerythritol?

Suppliers quote Dithioerythritol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dithioerythritol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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