CompoundList
Sign in
Other active pharmaceutical ingredients

Doxercalciferol

Also known as Hectorol, 1-Hydroxyergocalciferol, 1alpha-Hydroxyergocalciferol

CAS 54573-75-0Formula C28H44O2Molar mass 412.66 g/molEC 643-005-9
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 31 suppliers listed Drug substance
Get quotes Compare 31 suppliers
Doxercalciferol chemical structure, C28H44O2, CAS 54573-75-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
54573-75-0
Formula
C28H44O2
Molar mass
412.66 g/mol
EC number
643-005-9
HS code
290619
Category
Other active pharmaceutical ingredients

What is Doxercalciferol?

Plain description, key identifiers and synonyms

Doxercalciferol is a hydroxy seco-steroid and synthetic vitamin D2 analogue that undergoes metabolic activation in vivo to form 1alpha,25-dihydroxyvitamin D2 (1alpha,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. It is used to treat secondary hyperparathyroidism, a condition in which the body produces excess parathyroid hormone (PTH, a natural substance needed to control the amount of calcium in the blood) in certain people with chronic kidney disease. It has a role as a provitamin, a bone density conservation agent and a prohormone. It is a vitamin D and a hydroxy seco-steroid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
CAS number
54573-75-0 CAS number cross-checked
EC number
643-005-9
Molecular formula
C28H44O2
UNII
3DIZ9LF5Y9
MDL number
MFCD00871065
InChIKey
HKXBNHCUPKIYDM-CGMHZMFXSA-N
InChI
InChI=1S/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1
Canonical SMILES
C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)C=CC(C)C(C)C)CC(O)CC1O
Isomeric SMILES
C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C

Synonyms

  • Hectorol
  • 1-Hydroxyergocalciferol
  • 1alpha-Hydroxyergocalciferol
  • 1alpha-hydroxyvitamin D2
  • 1-alpha-Hydroxyvitamin D2
  • 1-alpha-hydroxyergocalciferol
  • Doxercalciferolum
  • (1S,3R,5Z,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraene-1,3-diol
  • doxacalciferol
  • 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol, (1alpha,3beta,5Z,7E,22E)-
  • 1alpha-OHD2
  • 1alpha(OH)2D2
  • 1 alpha-hydroxyergocalciferol
  • (1alpha,3beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol
  • (5Z,7E,22E)-(3S,5R,24S)-9,10-seco-5,7,10(19),22-ergostatetraen-3,24-diol
  • 1-Hydroxyvitamin D2
  • TSA 840
  • 1alpha-OH-D2
  • trans-Doxercalciferol
  • 1a-Hydroxy Vitamin D2
  • 1-Hydroxy Vitamin D2, Doxercalciferol
  • (5Z,7E,22E)-(1S,3R)-9,10-seco-5,7,10(19),22-ergostatetraene-1,3-diol
  • Hectorol (TN)
  • Vitamin D2, 1alpha-Hydroxy-
  • 1alpha-hydroxy vitamin D2
Show all 31 synonyms
  • 1alphaOHD2
  • (1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
  • Vitamin Impurity 34
  • (5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1alpha,3beta-diol
  • 1alpha-hydroxyvitamin D2 / 1alpha-hydroxyergocalciferol
  • 1-alpha-hydroxy-vitamin D2

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
412.66 g/molcalc.
Exact mass
412.3341 Dacalc.
LogP (octanol/water)
6.61calc.
Topological polar surface area
40.46 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
5calc.
Heavy atoms
30calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.71calc.
Formal charge
0calc.
Stereocentres
7calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C=C1CCCCC1=CC=C1CCCC2CCCC12

C=C1CCCCC1=CC=C1CCCC2CCCC12

3 rings, 18 atoms.

569 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Doxercalciferol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 31 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

31 suppliers in 9 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Doxercalciferol price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Bone Density Conservation Agents
  • Vitamins

Roles

  • antineoplastic agent
  • antipsoriatic
  • bone density conservation agent
  • dermatologic drug
  • pharmaceutical
  • prohormone
  • provitamin

Pharmacology

Doxercalciferol is a Vitamin D2 Analog.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Doxercalciferol is traded under.

HS 2906.19Indicative HS code

Cyclanic, cyclenic or cycloterpenic, other

World exports in 2024
$613M
+18.7% vs 2023, imports $606M
2019 to 2024
Top exporters
  1. China34.2%
  2. India * partner reported10.1%
  3. Germany9.5%
Top importers
  1. United States19.8%
  2. Germany9.0%
  3. India * partner reported8.4%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Doxercalciferol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Doxercalciferol, based on the data on this page

What is Doxercalciferol?

Doxercalciferol is a hydroxy seco-steroid and synthetic vitamin D2 analogue that undergoes metabolic activation in vivo to form 1alpha,25-dihydroxyvitamin D2 (1alpha,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2.

What is the CAS number of Doxercalciferol?

The CAS registry number of Doxercalciferol is 54573-75-0.

What is the molecular formula and weight of Doxercalciferol?

The molecular formula of Doxercalciferol is C28H44O2 and its molar mass is 412.66 g/mol.

What is Doxercalciferol used for?

Known uses and roles of Doxercalciferol include vitamins and supplements in pharmaceuticals, vitamins, minerals and nutrients in food and beverage, antineoplastic agent, antipsoriatic, bone density conservation agent and 6 more.

Is Doxercalciferol hazardous?

Doxercalciferol carries the GHS signal word "Danger". Main hazards: fatal if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Doxercalciferol?

Doxercalciferol is usually classified under HS code 290619 (Cyclanic, cyclenic or cycloterpenic, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Doxercalciferol?

CompoundList lists 31 suppliers of Doxercalciferol in China, India, United States, Switzerland and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Doxercalciferol in India?

6 suppliers in India list Doxercalciferol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Doxercalciferol?

Suppliers quote Doxercalciferol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Doxercalciferol

Get quotes for Doxercalciferol

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Doxercalciferol
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Doxercalciferol with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/doxercalciferol-54573-75-0" title="Doxercalciferol structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Other active pharmaceutical ingredients or HS code 290619

31 suppliers
Free quotes, contact stays private
Get quotes