Droxicam
Also known as Droxicamum, 5-methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)dione-6,6-dioxide, 8-methyl-5-(pyridin-2-yl)-3-oxa-9??-thia-5,8-diazatricyclo(8.4.0.02,?)tetradeca-1(14),2(7),10,12-tetraene-4,6,9,9-tetrone
Key facts
What buyers check first
- CAS number
- 90101-16-9
- Formula
- C16H11N3O5S
- Molar mass
- 357.35 g/mol
- HS code
- 293590
- Category
- Analgesics and anti-inflammatories
What is Droxicam?
Plain description, key identifiers and synonyms
Droxicam is an organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respectively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, a prodrug, a platelet aggregation inhibitor, a cyclooxygenase 1 inhibitor and a hepatotoxic agent. It is a member of pyridines and an organic heterotricyclic compound. It is functionally related to a piroxicam.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
- CAS number
- 90101-16-9 CAS number cross-checked
- Molecular formula
- C16H11N3O5S
- UNII
- F24ADO1E2D
- MDL number
- MFCD00866032
- InChIKey
- OEHFRZLKGRKFAS-UHFFFAOYSA-N
- InChI
- InChI=1S/C16H11N3O5S/c1-18-13-14(10-6-2-3-7-11(10)25(18,22)23)24-16(21)19(15(13)20)12-8-4-5-9-17-12/h2-9H,1H3
- SMILES (canonical and isomeric)
- CN1C2=C(C3=CC=CC=C3S1(=O)=O)OC(=O)N(C2=O)C4=CC=CC=N4
Synonyms
- Droxicamum
- 5-methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)dione-6,6-dioxide
- 8-methyl-5-(pyridin-2-yl)-3-oxa-9??-thia-5,8-diazatricyclo(8.4.0.02,?)tetradeca-1(14),2(7),10,12-tetraene-4,6,9,9-tetrone
- 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxide
- 5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
- Ombolan
- Droxicam (INN)
- 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino-[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxide
- 5-Methyl-3-(pyridin-2-yl)-3-hydro-2H,5H-benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4-dione 6,6-dioxide
- precam
- Drogelon
- Ferpan
- 5-Methyl-3-(2-pyridinyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)-dione 6,6-dioxide
- 5-methyl-6,6-dioxo-3-(2-pyridyl)-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
- 2H,5H-1,3-Oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)-dione, 5-methyl-3-(2-pyridinyl)-, 6,6-dioxide
- 5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)-dione 6,6-dioxide
- 5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino(5,6-))(1,2)benzothiazine-2,4(3H)-dione 6,6-dioxide
- 5-methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4-(3H)dione-6,6-dioxide
- 5-methyl-3-(pyridin-2-yl)-2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
- 5-Methyl-3-(pyridin-2-yl)-2H-6lambda~6~-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4,6,6(3H,5H)-tetrone
- 8-methyl-5-(pyridin-2-yl)-3-oxa-9$l^{6}-thia-5,8-diazatricyclo[8.4.0.0^{2,7}]tetradeca-1(10),2(7),11,13-tetraene-4,6,9,9-tetrone
- 8-methyl-5-(pyridin-2-yl)-3-oxa-9lambda6-thia-5,8-diazatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2(7),10,12-tetraene-4,6,9,9-tetrone
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 357.35 g/molcalc.Computed value |
|---|---|
| Exact mass | 357.0419 Dacalc.Computed value |
| LogP (octanol/water) | 0.99calc.Computed value |
| Topological polar surface area | 102.5 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 1calc.Computed value |
| Heavy atoms | 25calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 3calc.Computed value |
| Fraction sp3 carbons | 0.06calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=c1oc2c(c(=O)n1-c1ccccn1)NS(=O)(=O)c1ccccc1-2
4 rings, 24 atoms.
No other chemical in our database has this scaffold.
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Droxicam suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, WuhanUnclaimed profileDroxicamGrade, purity and minimum order on requestPrice on request
- United States, WatertownUnclaimed profileDroxicamGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
2 suppliers in 2 countries
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Droxicam price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Anti-Inflammatory Agents, Non-Steroidal
Roles
- aetiopathogenetic role
- analgesic
- anti-inflammatory agent
- anti-inflammatory drug
- antirheumatic drug
- cyclooxygenase 1 inhibitor
- enzyme inhibitor
- hematologic agent
- hepatotoxic agent
- non-narcotic analgesic
- non-steroidal anti-inflammatory drug
- pharmaceutical
- platelet aggregation inhibitor
- pro-agent
- prodrug
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Droxicam is traded under.
Sulphonamides, other
- United States23.6%
- Slovenia19.1%
- Spain11.7%
* Partner reported figures, a lower bound.
The HS code shown for Droxicam is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Droxicam, based on the data on this page
What is Droxicam?
What is the CAS number of Droxicam?
What is the molecular formula and weight of Droxicam?
What is Droxicam used for?
Is Droxicam hazardous?
What is the HS code of Droxicam?
Where can I buy Droxicam?
What is the price of Droxicam?
Guides for buyers
Practical guides that help when you source, ship or handle Droxicam
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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