CompoundList
Sign in
Analgesics and anti-inflammatories

Ebselen

Also known as 2-Phenyl-1,2-benzisoselenazol-3(2H)-one, 2-phenyl-1,2-benzoselenazol-3-one, Ebselene

CAS 60940-34-3Formula C13H9NOSeMolar mass 274.18 g/molEC 612-054-8
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard, Hazardous to the environment 70 suppliers listed
Get quotes Compare 70 suppliers
Ebselen chemical structure, C13H9NOSe, CAS 60940-34-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
60940-34-3
Formula
C13H9NOSe
Molar mass
274.18 g/mol
EC number
612-054-8
HS code
293499
Category
Analgesics and anti-inflammatories

What is Ebselen?

Plain description, key identifiers and synonyms

Ebselen is a benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an anticoronaviral agent, a ferroptosis inhibitor, an EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor, an antioxidant, an antibacterial agent, an anti-inflammatory drug, an antineoplastic agent, an antifungal agent, a radical scavenger, a genotoxin, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, a hepatoprotective agent, a neuroprotective agent, an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, an apoptosis inducer, an EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor, an enzyme mimic, an EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor, an EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor, an EC 3.5.4.1 (cytosine deaminase) inhibitor and an EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-phenyl-1,2-benzoselenazol-3-one
CAS number
60940-34-3 CAS number cross-checked
EC number
612-054-8
Molecular formula
C13H9NOSe
UNII
40X2P7DPGH
MDL number
MFCD00210937
InChIKey
DYEFUKCXAQOFHX-UHFFFAOYSA-N
InChI
InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
SMILES (canonical and isomeric)
C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2

Synonyms

  • 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
  • 2-phenyl-1,2-benzoselenazol-3-one
  • Ebselene
  • Ebseleno
  • Ebselenum
  • PZ 51
  • 2-phenyl-1,2-benzoisoselenazol-3(2H)-one
  • 2-phenyl-2,3-dihydro-1,2-benzoselenazol-3-one
  • SPI 1005
  • 2-phenylbenzoisoselenazol-3(2H)-one
  • 2-phenylbenzo[d][1,2]selenazol-3(2H)-one
  • Harmokisane
  • C13H9NOSe
  • 1,2-Benzisoselenazol-3(2H)-one, 2-phenyl-
  • DR 3305
  • 2-Phenyl-1,2-benzisoselenazolin-3-one
  • 2-phenyl-1,2-benzoselenazol-3(2h)-one
  • DivK1c_000951
  • Bio2_000062
  • Bio2_000542
  • RP 60931
  • 2-Phenyl-1,2-benzoselenazol-3-one (Ebselen)
  • Ebselen?
  • 2-Phenyl-1,2-benzoisoselenazol-3(2H)-one, CCG-39161, Ebselen, Lopac E 3520, NSC 639762, PZ 51
  • Ebselen (C5)
Show all 27 synonyms
  • nchembio.109-comp1
  • Ebeselen

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
274.18 g/molcalc.
Exact mass
274.9849 Dacalc.
LogP (octanol/water)
2.05calc.
Topological polar surface area
22 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
1calc.
Heavy atoms
16calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1c2ccccc2[se]n1-c1ccccc1

O=c1c2ccccc2[se]n1-c1ccccc1

3 rings, 16 atoms. This chemical is the scaffold itself.

32 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H301Toxic if swallowed.
  • H331Toxic if inhaled.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (16)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ebselen suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 70 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

70 suppliers in 12 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Ebselen price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal
  • Anti-Ulcer Agents
  • Antioxidants
  • Cyclooxygenase Inhibitors
  • Neuroprotective Agents

Roles

  • anti-inflammatory agent
  • anti-inflammatory drug
  • antibacterial agent
  • anticoronaviral agent
  • antidepressant
  • antifungal agent
  • antineoplastic agent
  • antioxidant
  • antipsychotic agent
  • antiviral agent
  • apoptosis inducer
  • central nervous system depressant
  • central nervous system drug
  • enzyme mimic
  • ferroptosis inhibitor
  • genotoxin
  • hepatoprotective agent
  • hypoglycemic agent
  • neuroprotective agent
  • pharmaceutical
  • protective agent
  • psychotropic drug
  • radical scavenger
  • tranquilizing drug

Pharmacology

Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ebselen is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Ebselen is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ebselen, based on the data on this page

What is Ebselen?

Ebselen is a benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

What is the CAS number of Ebselen?

The CAS registry number of Ebselen is 60940-34-3.

What is the molecular formula and weight of Ebselen?

The molecular formula of Ebselen is C13H9NOSe and its molar mass is 274.18 g/mol.

What is Ebselen used for?

Known uses and roles of Ebselen include anti-inflammatories in pharmaceuticals, anti-inflammatory agent, anti-inflammatory drug, antibacterial agent, anticoronaviral agent and 25 more.

Is Ebselen hazardous?

Ebselen carries the GHS signal word "Danger". Main hazards: toxic if swallowed, toxic if inhaled, may cause damage to organs through prolonged or repeated exposure. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ebselen?

Ebselen is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ebselen?

CompoundList lists 70 suppliers of Ebselen in United States, China, United Kingdom, Germany and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ebselen?

Suppliers quote Ebselen on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ebselen

Get quotes for Ebselen

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Ebselen
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Ebselen with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/ebselen-60940-34-3" title="Ebselen structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Analgesics and anti-inflammatories or HS code 293499

70 suppliers
Free quotes, contact stays private
Get quotes