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Skin conditioning agents and actives

Eckol

Also known as 4-(3,5-dihydroxyphenoxy)dibenzo-p-dioxin-1,3,6,8-tetrol, 1-(3,5-Dihydroxyphenoxy)-2,4,7,9-tetrahydroxydibenzo-1,4-dioxin, 4-(3,5-dihydroxyphenoxy)oxanthrene-1,3,6,8-tetrol

CAS 88798-74-7Formula C18H12O9Molar mass 372.29 g/mol
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Eckol chemical structure, C18H12O9, CAS 88798-74-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
88798-74-7
Formula
C18H12O9
Molar mass
372.29 g/mol
HS code
293299
Category
Skin conditioning agents and actives

What is Eckol?

Plain description, key identifiers and synonyms

Eckol is a phlorotannin that is oxanthrene-1,3,6,8-tetrol substituted by a 3,5-dihydroxyphenoxy moiety at position 4. Isolated from the marine brown alga, Ecklonia cava, it exhibits antioxidant activity. It has a role as an antioxidant and a metabolite. It is functionally related to a phloroglucinol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-(3,5-dihydroxyphenoxy)dibenzo-p-dioxin-1,3,6,8-tetrol
CAS number
88798-74-7 CAS number cross-checked
Molecular formula
C18H12O9
UNII
4A5E8354UB
INCI name
ECKOL
InChIKey
PCZZRBGISTUIOA-UHFFFAOYSA-N
InChI
InChI=1S/C18H12O9/c19-7-1-8(20)3-10(2-7)25-16-12(23)6-13(24)17-18(16)27-15-11(22)4-9(21)5-14(15)26-17/h1-6,19-24H
SMILES (canonical and isomeric)
C1=C(C=C(C=C1O)OC2=C(C=C(C3=C2OC4=C(C=C(C=C4O3)O)O)O)O)O

Synonyms

  • 4-(3,5-dihydroxyphenoxy)dibenzo-p-dioxin-1,3,6,8-tetrol
  • 1-(3,5-Dihydroxyphenoxy)-2,4,7,9-tetrahydroxydibenzo-1,4-dioxin
  • 4-(3,5-dihydroxyphenoxy)oxanthrene-1,3,6,8-tetrol
  • 4-(3,5-dihydroxyphenoxy)-dibenzo(b,e)(1,4)dioxin-1,3,6,8-tetrol
  • 4-(3,5-Dihydroxyphenoxy)dibenzo[b,e][1,4]dioxine-1,3,6,8-tetraol
  • Dibenzo[b,e][1,4]dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-
  • Dibenzo(b,E)(1,4)dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-
  • 4-(3,5-Dihydroxyphenoxy)dibenzo(b,E)(1,4)dioxin-1,3,6,8-tetrol
  • Dibenzo(b,e)(1,4)-dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
372.29 g/molcalc.
Exact mass
372.0481 Dacalc.
LogP (octanol/water)
3.61calc.
Topological polar surface area
149.1 Ųcalc.
Hydrogen bond donors
6calc.
Hydrogen bond acceptors
9calc.
Rotatable bonds
2calc.
Heavy atoms
27calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Oc2cccc3c2Oc2ccccc2O3)cc1

c1ccc(Oc2cccc3c2Oc2ccccc2O3)cc1

4 rings, 21 atoms.

No other chemical in our database has this scaffold.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Eckol suppliers

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Eckol price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name ECKOL(hair conditioning, skin protecting, skin conditioning - miscellaneous)

Roles

  • antioxidant
  • metabolite

Cosmetic functions

  • Hair conditioning
  • Skin conditioning - miscellaneous
  • Skin protecting

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Eckol is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Eckol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Eckol, based on the data on this page

What is Eckol?

Eckol is a phlorotannin that is oxanthrene-1,3,6,8-tetrol substituted by a 3,5-dihydroxyphenoxy moiety at position 4. Isolated from the marine brown alga, Ecklonia cava, it exhibits antioxidant activity. It has a role as an antioxidant and a metabolite. It is functionally related to a phloroglucinol.

What is the CAS number of Eckol?

The CAS registry number of Eckol is 88798-74-7.

What is the molecular formula and weight of Eckol?

The molecular formula of Eckol is C18H12O9 and its molar mass is 372.29 g/mol.

What is Eckol used for?

Known uses and roles of Eckol include skin conditioning agents in cosmetics and personal care, hair conditioning agents in cosmetics and personal care, antioxidant, metabolite, hair conditioning and 2 more.

Is Eckol hazardous?

No GHS hazard classification for Eckol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Eckol?

Eckol is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Eckol?

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What is the price of Eckol?

Suppliers quote Eckol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Eckol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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