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Cosmetic antioxidants

Epicatechin

Also known as (-)-Epicatechin, L-Epicatechin, Epicatechol

CAS 490-46-0Formula C15H14O6Molar mass 290.27 g/molEC 207-710-1
GHS signal word: Warning. Pictograms: Harmful or irritant 97 suppliers listed
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Epicatechin chemical structure, C15H14O6, CAS 490-46-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
490-46-0
Formula
C15H14O6
Molar mass
290.27 g/mol
EC number
207-710-1
HS code
293299
Category
Cosmetic antioxidants

What is Epicatechin?

Plain description, key identifiers and synonyms

(-)-epicatechin is a catechin with (2R,3R)-configuration. It has a role as an antioxidant. It is a catechin and a polyphenol. It is an enantiomer of a (+)-epicatechin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
CAS number
490-46-0 CAS number cross-checkedOther or deprecated CAS: 17334-50-8, 7295-85-4
EC numbers
207-710-1, 230-731-2
Molecular formula
C15H14O6
UNII
34PHS7TU43
MDL number
MFCD00075648
INCI name
EPICATECHIN
InChIKey
PFTAWBLQPZVEMU-UKRRQHHQSA-N
InChI
InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1
Canonical SMILES
Oc1cc(O)c2c(c1)OC(c1ccc(O)c(O)c1)C(O)C2
Isomeric SMILES
C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O

Synonyms

  • (-)-Epicatechin
  • L-Epicatechin
  • Epicatechol
  • epi-Catechin
  • epi-Catechol
  • l-Acacatechin
  • (-)-Epicatechol
  • (2R,3R)-(-)-Epicatechin
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
  • (-)-epi catechin
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
  • (-)-(2R:3R)-5,7,3',4'-Tetrahydroxyflavan-3-ol
  • 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3R)-
  • 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-cis)-
  • (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol
  • (2R-cis)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
  • (2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol
  • alpha Catechin
  • (?)-Epicatechin
  • Epicatechol, (-)-
  • 2-(3,4-Dihydroxyphenyl)-2,3,4-trihydro-3,5,7-trihydroxychromene
  • (-)-Epicatechin (Standard)
  • (2R,3R)-2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol
  • 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-,(2R,3R)-
  • (-)-cis-Epicatechin
Show all 38 synonyms
  • alpha-catechin
  • Acacatechin
  • Colatein
  • Epicatechin-(-)
  • Acacatechin,
  • Epicatechol,
  • Kakaol,
  • Teacatechin I,
  • EC,L-Epicatechin
  • (-)-epicatechine
  • L(-)-Epicatechin
  • (+-)-epicatechin
  • 2,3-cis-epicatechin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
290.27 g/molcalc.
Exact mass
290.079 Dacalc.
LogP (octanol/water)
1.55calc.
Topological polar surface area
110.4 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
1calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.2calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C2CCc3ccccc3O2)cc1

c1ccc(C2CCc3ccccc3O2)cc1

3 rings, 16 atoms, the Flavan ring system.

326 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Epicatechin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 97 suppliers
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Where suppliers are based

97 suppliers in 17 countries

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Epicatechin price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name EPICATECHIN(antioxidant, astringent, deodorant, hair dyeing)

Roles

  • antioxidant

Cosmetic functions

  • Antioxidant
  • Astringent
  • Deodorant
  • Hair dyeing
  • Oral care
  • Skin conditioning - miscellaneous
  • Skin protecting

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Epicatechin is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Epicatechin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Epicatechin, based on the data on this page

What is Epicatechin?

(-)-epicatechin is a catechin with (2R,3R)-configuration. It has a role as an antioxidant. It is a catechin and a polyphenol. It is an enantiomer of a (+)-epicatechin.

What is the CAS number of Epicatechin?

The CAS registry number of Epicatechin is 490-46-0. Other or deprecated CAS numbers: 17334-50-8, 7295-85-4.

What is the molecular formula and weight of Epicatechin?

The molecular formula of Epicatechin is C15H14O6 and its molar mass is 290.27 g/mol.

What is Epicatechin used for?

Known uses and roles of Epicatechin include antioxidants in cosmetics and personal care, skin conditioning agents in cosmetics and personal care, colorants in cosmetics and personal care, antioxidant, astringent and 5 more.

Is Epicatechin hazardous?

Epicatechin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Epicatechin?

Epicatechin is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Epicatechin?

CompoundList lists 97 suppliers of Epicatechin in United States, China, Germany, United Kingdom and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Epicatechin in India?

1 supplier in India list Epicatechin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Epicatechin?

Suppliers quote Epicatechin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Epicatechin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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