Ethchlorvynol
Also known as Ethchlorovynol, Alvinol, Arvynol
Key facts
What buyers check first
- Appearance
- Colorless to yellow liquid
- Boiling point
- 173 to 174
- Density
- 1.065-1.070 @ 25 °C/4 °C
- Solubility
- IMMISCIBLE WITH WATER, MISCIBLE WITH MOST ORG SOLVENTS
- HS code
- 290551
- Category
- Alcohols and polyols

What is Ethchlorvynol?
Plain description, key identifiers and synonyms
Ethchlorvynol is propargyl alcohol in which the methylene hydrogens are substituted by ethyl and 2-chlorovinyl groups. A hypnotic and sedative, it is used for treatment of insomnia in some cases where an intolerance or allergy to more commonly used drugs exists. It has a role as a sedative. It is a tertiary alcohol, an organochlorine compound, an enyne and a terminal acetylenic compound.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol
- CAS number
- 113-18-8 CAS number cross-checked
- EC number
- 810-759-7
- Molecular formula
- C7H9ClO
- UNII
- 6EIM3851UZ
- InChIKey
- ZEHYJZXQEQOSON-AATRIKPKSA-N
- InChI
- InChI=1S/C7H9ClO/c1-3-7(9,4-2)5-6-8/h1,5-6,9H,4H2,2H3/b6-5+
- Canonical SMILES
- C#CC(O)(C=CCl)CC
- Isomeric SMILES
- CCC(/C=C/Cl)(C#C)O
Synonyms
- Ethchlorovynol
- Alvinol
- Arvynol
- Placidyl
- Normoson
- Roeridorm
- Nostel
- Ethchlorvinol
- Ethclorvynol
- Ethochlorvynol
- Serensil
- Etchlorvinolo
- Ethchlorvinyl
- Ethychlorvynol
- Serenesil
- Aethyl-chlorvynol
- Etclorvinol
- Normonson
- Normosan
- Placidil
- Serenil
- Ethchlorvynolum
- 1-Chloro-3-ethyl-1-penten-4-yn-3-ol
- 1-Penten-4-yn-3-ol, 1-chloro-3-ethyl-
- 3-(beta-Chlorovinyl)-1-pentyn-3-ol
Show all 37 synonymsShow fewer synonyms
- beta-Chlorovinyl ethyl ethynyl carbinol
- Ethyl beta-chlorovinyl ethynyl carbinol
- Ethchlorvynol civ
- 1-chloro-3-ethylpent-1-en-4-yn-3-ol
- 1-Chloro-3-ethylpent-1-4-yn-3-ol
- beta-Chlorvinyl ethyl ethynyl carbinol
- 5-Chloro-3-ethylpent-1-yn-4-en-3-ol
- 1-chloro-3-ethyl-pent-1-en-4-yn-3-ol
- (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol
- etclorvinolo
- (E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol
- Serensiloline
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Colorless to yellow liquidexp.Measured value |
|---|---|
| Odour | PUNGENT AROMATIC ODORexp.Measured value |
| Boiling point | 173 to 174exp.Measured value |
| Density | 1.065-1.070 @ 25 °C/4 °Cexp.Measured value |
| Solubility | IMMISCIBLE WITH WATER, MISCIBLE WITH MOST ORG SOLVENTSexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 144.60 g/molcalc.Computed value |
|---|---|
| Exact mass | 144.0342 Dacalc.Computed value |
| LogP (octanol/water) | 1.51calc.Computed value |
| Topological polar surface area | 20.23 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 9calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.43calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H301Toxic if swallowed.
Precautionary statements (7)
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P301 + P316If swallowed: Get emergency medical help immediately.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidEthchlorvynol suppliers
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- India, VadodaraUnclaimed profileEthclorvynolGrade, purity and minimum order on requestPrice on request
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Ethchlorvynol price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Hypnotics and Sedatives
Roles
- central nervous system depressant
- central nervous system drug
- pharmaceutical
- sedative
Pharmacology
Ethchlorvynol is a member of the class of tertiary carbinols with sedative and hypnotic properties. Ethchlorvynol appears to depress the central nervous system by binding at a benzodiazepine-GABA-A-chloride ionophore receptor complex, located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS). This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability.
How it is made
By reacting ethyl chlorovinyl ketone with lithium acetylide under grignard reaction conditions. Alkoxide addn complex reacts readily with dil acid to form crude ethchlorvynol which is extracted with suitable ... Organic solvent such as ether & is subsequently purified by distillation.
Regulatory status
Inventories, regulations and trade controls that list this substance
Controls
- US DEA controlled substance or listed chemical
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Ethchlorvynol is traded under.
Ethchlorvynol (INN)
- Netherlands87.1%
- India * partner reported8.0%
- France * partner reported4.8%
- France * partner reported45.5%
- Italy34.2%
- United Kingdom17.2%
* Partner reported figures, a lower bound.
The HS code shown for Ethchlorvynol is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Ethchlorvynol, based on the data on this page
What is Ethchlorvynol?
What is the CAS number of Ethchlorvynol?
What is the molecular formula and weight of Ethchlorvynol?
What is Ethchlorvynol used for?
Is Ethchlorvynol hazardous?
What is the HS code of Ethchlorvynol?
Where can I buy Ethchlorvynol?
Where can I buy Ethchlorvynol in India?
What is the price of Ethchlorvynol?
Guides for buyers
Practical guides that help when you source, ship or handle Ethchlorvynol
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
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