Ethylvanillin
Also known as 3-Ethoxy-4-hydroxybenzaldehyde, Ethyl vanillin, Vanillal
Key facts
What buyers check first
- Appearance
- Fine, crystalline needles
- Melting point
- 76.7 °C
- Boiling point
- 285 °C
- Flash point
- 145 °C
- Solubility
- In water, 2,822 mg/L at 25 °C
- HS code
- 291242
- Category
- Flavor ingredients

What is Ethylvanillin?
Plain description, key identifiers and synonyms
Ethyl vanillin is a member of the class of benzaldehydes that is vanillin in which the methoxy group is replaced by an ethoxy group. It has a role as an antioxidant and a flavouring agent. It is a member of benzaldehydes, a member of phenols and an aromatic ether. It is functionally related to a vanillin.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 3-ethoxy-4-hydroxybenzaldehyde
- CAS number
- 121-32-4 CAS number cross-checked
- EC number
- 204-464-7
- Molecular formula
- C9H10O3
- UNII
- YC9ST449YJ
- MDL number
- MFCD00006944
- INCI name
- ETHYL VANILLIN
- InChIKey
- CBOQJANXLMLOSS-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H10O3/c1-2-12-9-5-7(6-10)3-4-8(9)11/h3-6,11H,2H2,1H3
- SMILES (canonical and isomeric)
- CCOC1=C(C=CC(=C1)C=O)O
Synonyms
- 3-Ethoxy-4-hydroxybenzaldehyde
- Ethyl vanillin
- Vanillal
- Ethylprotal
- Bourbonal
- Ethavan
- Ethovan
- Vanirom
- Vanilal
- Quantrovanil
- 4-Hydroxy-3-ethoxybenzaldehyde
- Benzaldehyde, 3-ethoxy-4-hydroxy-
- Rhodiarome
- Vanillin, ethyl-
- Ethyl protal
- Protocatechuic aldehyde ethyl ether
- Vanirome
- 2-Ethoxy-4-formylphenol
- Arovanillon
- Ethylprotocatechuic aldehyde
- 3-Ethoxyprotocatechualdehyde
- Ethyl protocatechuic aldehyde
- Vanillin,ethyl
- Quantrovanil, Vanillal
- Vanbeenol
Show all 33 synonymsShow fewer synonyms
- ethyl-vanillin
- Ethylprotocatechualdehyde-3-ethyl ether
- 3-Ethoxy-4-hydroxy-benzaldehyde
- 3-ethoxy-4-hydroxy benzaldehyde
- Ethyl vanillin (NF)
- Protocatechuic aldehyde 3-ethyl ether
- ehtylvanillin
- Aethylvanillin
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Fine, crystalline needlesexp.Measured value |
|---|---|
| Odour | Finer and more intense vanillaexp.Measured value |
| Taste | Sweetexp.Measured value |
| Melting point | 76.7 °Cexp.Measured value |
| Boiling point | 285 °Cexp.Measured value |
| Flash point | 145 °Cexp.Measured value |
| Solubility | In water, 2,822 mg/L at 25 °Cexp.Measured value |
| Vapour pressure | 1.04 × 10⁻⁵ mm Hg at 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 166.18 g/molcalc.Computed value |
|---|---|
| Exact mass | 166.063 Dacalc.Computed value |
| LogP (octanol/water) | 1.6calc.Computed value |
| Topological polar surface area | 46.53 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 3calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 12calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.22calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H319Causes serious eye irritation.
Precautionary statements (4)
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P337 + P317If eye irritation persists: Get medical help.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidEthylvanillin suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, MumbaiUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- China, JiaxingUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- China, JiaxingUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- Japan, Chiyoda-KuUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- Italy, Belpasso ManufacturerUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- Thailand, Lat KrabangUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- Poland, WołówUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- Jiaxing City letter Rong Trade and Industry Limited (the letter Zhejiang Import and Export Co. Ltd.)China, JiaxingUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- China, HangzhouUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
- India, BengaluruUnclaimed profileEthylvanillinGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
139 suppliers in 25 countries
- China41
- United States27
- India24
- Canada9
- Philippines3
- Belgium2
- and 19 more countries
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Ethylvanillin price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
In flavoring and perfumery.
Used as a chemical intermediate.
Flavors, to replace or fortify vanillin.
Reported uses (ppm):
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#2519].
Ethyl vanillin is used extensively in the chocolate industry. It gives a sweet, balsamic note to flowery and fruity perfume compositions.
Industrial uses: Fragrance, Flavoring and nutrient.
Consumer uses: Fragrance.
Use classes: Cosmetics.
Industries and functions
- Skin conditioning agents in cosmetics and personal care
- Fragrance ingredients in cosmetics and personal care
- Flavors in food and beverage
- Flavors and palatants in animal feed and nutrition
- Flavoring agents in flavors and fragrances
- Fragrance ingredients in flavors and fragrances
- Phenolic and vanillic notes in flavors and fragrances
Cosmetic ingredient, INCI name ETHYL VANILLIN(fragrance, soothing)
Roles
- additive
- antioxidant
- flavouring agent
- food additive
- food component
- physiological role
Functional uses
- Deodorizer
- Flavouring and nutrient
- Fragrance
- Humectant
- pH regulating agent
Cosmetic functions
- Fragrance
- Soothing
How it is made
From safrole by isomerization to isosafrole and subsequent oxidation to piperonal, the methylene linkage is then broken by heating piperonal in an alcoholic solution of KOH, finally the resulting protocatechualdehyde is reacted with ethyl alcohol.
From guaethol by condensation with chloral to yield 3-ethoxy-4-hydroxyphenyl trichloromethyl carbinol, this is then boiled with an alcoholic solution of KOH or NaOH, acidified, and extracted with chloroform to yield ethyl vanillin.
By reacting o-ethoxyphenol with formaldehyde and p-nitrosodimethylaniline in the presence of aluminum and water.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Ethylvanillin is traded under.
Ethylvanillin (3-ethoxy-4-hydroxybenzaldehyde)
- China57.4%
- United States23.7%
- Germany5.5%
* Partner reported figures, a lower bound.
The HS code shown for Ethylvanillin is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Ethylvanillin, based on the data on this page
What is Ethylvanillin?
What is the CAS number of Ethylvanillin?
What is the molecular formula and weight of Ethylvanillin?
What is Ethylvanillin used for?
Is Ethylvanillin hazardous?
What is the HS code of Ethylvanillin?
Where can I buy Ethylvanillin?
Where can I buy Ethylvanillin in India?
What is the price of Ethylvanillin?
Guides for buyers
Practical guides that help when you source, ship or handle Ethylvanillin
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Article, FormulationHow to choose a cosmetic emulsifierA structured way to choose an emulsifier for creams and lotions: emulsion type, HLB and its limits, emulsifier families, formula fit, stability testing and what to ask suppliers.Read
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