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Ethylvanillin

Also known as 3-Ethoxy-4-hydroxybenzaldehyde, Ethyl vanillin, Vanillal

Ethylvanillin chemical structure, C9H10O3, CAS 121-32-4
2D chemical structure

Key facts

What buyers check first

Appearance
Fine, crystalline needles
Melting point
76.7 °C
Boiling point
285 °C
Flash point
145 °C
Solubility
In water, 2,822 mg/L at 25 °C
HS code
291242
Category
Flavor ingredients
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Ethylvanillin?

Plain description, key identifiers and synonyms

Ethyl vanillin is a member of the class of benzaldehydes that is vanillin in which the methoxy group is replaced by an ethoxy group. It has a role as an antioxidant and a flavouring agent. It is a member of benzaldehydes, a member of phenols and an aromatic ether. It is functionally related to a vanillin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-ethoxy-4-hydroxybenzaldehyde
CAS number
121-32-4 CAS number cross-checked
EC number
204-464-7
Molecular formula
C9H10O3
UNII
YC9ST449YJ
MDL number
MFCD00006944
INCI name
ETHYL VANILLIN
InChIKey
CBOQJANXLMLOSS-UHFFFAOYSA-N
InChI
InChI=1S/C9H10O3/c1-2-12-9-5-7(6-10)3-4-8(9)11/h3-6,11H,2H2,1H3
SMILES (canonical and isomeric)
CCOC1=C(C=CC(=C1)C=O)O

Synonyms

  • 3-Ethoxy-4-hydroxybenzaldehyde
  • Ethyl vanillin
  • Vanillal
  • Ethylprotal
  • Bourbonal
  • Ethavan
  • Ethovan
  • Vanirom
  • Vanilal
  • Quantrovanil
  • 4-Hydroxy-3-ethoxybenzaldehyde
  • Benzaldehyde, 3-ethoxy-4-hydroxy-
  • Rhodiarome
  • Vanillin, ethyl-
  • Ethyl protal
  • Protocatechuic aldehyde ethyl ether
  • Vanirome
  • 2-Ethoxy-4-formylphenol
  • Arovanillon
  • Ethylprotocatechuic aldehyde
  • 3-Ethoxyprotocatechualdehyde
  • Ethyl protocatechuic aldehyde
  • Vanillin,ethyl
  • Quantrovanil, Vanillal
  • Vanbeenol
Show all 33 synonyms
  • ethyl-vanillin
  • Ethylprotocatechualdehyde-3-ethyl ether
  • 3-Ethoxy-4-hydroxy-benzaldehyde
  • 3-ethoxy-4-hydroxy benzaldehyde
  • Ethyl vanillin (NF)
  • Protocatechuic aldehyde 3-ethyl ether
  • ehtylvanillin
  • Aethylvanillin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Fine, crystalline needlesexp.
Odour
Finer and more intense vanillaexp.
Taste
Sweetexp.
Melting point
76.7 °Cexp.
Boiling point
285 °Cexp.
Flash point
145 °Cexp.
Solubility
In water, 2,822 mg/L at 25 °Cexp.
Vapour pressure
1.04 × 10⁻⁵ mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
166.18 g/molcalc.
Exact mass
166.063 Dacalc.
LogP (octanol/water)
1.6calc.
Topological polar surface area
46.53 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
12calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.22calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H319Causes serious eye irritation.
Precautionary statements (4)
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337 + P317If eye irritation persists: Get medical help.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ethylvanillin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 139 suppliers
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Where suppliers are based

139 suppliers in 25 countries

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Ethylvanillin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

In flavoring and perfumery.

Used as a chemical intermediate.

Flavors, to replace or fortify vanillin.

Reported uses (ppm):

Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#2519].

Ethyl vanillin is used extensively in the chocolate industry. It gives a sweet, balsamic note to flowery and fruity perfume compositions.

Industrial uses: Fragrance, Flavoring and nutrient.

Consumer uses: Fragrance.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name ETHYL VANILLIN(fragrance, soothing)

Roles

  • additive
  • antioxidant
  • flavouring agent
  • food additive
  • food component
  • physiological role

Functional uses

  • Deodorizer
  • Flavouring and nutrient
  • Fragrance
  • Humectant
  • pH regulating agent

Cosmetic functions

  • Fragrance
  • Soothing

How it is made

From safrole by isomerization to isosafrole and subsequent oxidation to piperonal, the methylene linkage is then broken by heating piperonal in an alcoholic solution of KOH, finally the resulting protocatechualdehyde is reacted with ethyl alcohol.

From guaethol by condensation with chloral to yield 3-ethoxy-4-hydroxyphenyl trichloromethyl carbinol, this is then boiled with an alcoholic solution of KOH or NaOH, acidified, and extracted with chloroform to yield ethyl vanillin.

By reacting o-ethoxyphenol with formaldehyde and p-nitrosodimethylaniline in the presence of aluminum and water.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ethylvanillin is traded under.

HS 2912.42Exact HS code

Ethylvanillin (3-ethoxy-4-hydroxybenzaldehyde)

World exports in 2024
$102M
+11.6% vs 2023, imports $111M
2019 to 2024
Top exporters
  1. China57.4%
  2. United States23.7%
  3. Germany5.5%
Top importers
  1. Germany10.1%
  2. Singapore9.6%
  3. France * partner reported9.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ethylvanillin is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ethylvanillin, based on the data on this page

What is Ethylvanillin?

Ethyl vanillin is a member of the class of benzaldehydes that is vanillin in which the methoxy group is replaced by an ethoxy group. It has a role as an antioxidant and a flavouring agent. It is a member of benzaldehydes, a member of phenols and an aromatic ether. It is functionally related to a vanillin.

What is the CAS number of Ethylvanillin?

The CAS registry number of Ethylvanillin is 121-32-4.

What is the molecular formula and weight of Ethylvanillin?

The molecular formula of Ethylvanillin is C9H10O3 and its molar mass is 166.18 g/mol.

What is Ethylvanillin used for?

In flavoring and perfumery. Used as a chemical intermediate. Flavors, to replace or fortify vanillin. Reported uses (ppm): Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#2519]. Ethyl vanillin is used extensively in the chocolate industry.

Is Ethylvanillin hazardous?

Ethylvanillin carries the GHS signal word "Warning". Main hazards: causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ethylvanillin?

Ethylvanillin is usually classified under HS code 291242 (Ethylvanillin (3-ethoxy-4-hydroxybenzaldehyde)). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ethylvanillin?

CompoundList lists 139 suppliers of Ethylvanillin in China, United States, India, Canada and 21 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ethylvanillin in India?

24 suppliers in India list Ethylvanillin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ethylvanillin?

Suppliers quote Ethylvanillin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ethylvanillin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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