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Faropenem

Also known as Fropenem, (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 106560-14-9Formula C12H15NO5SMolar mass 285.32 g/mol
Faropenem chemical structure, C12H15NO5S, CAS 106560-14-9
2D chemical structure

Key facts

What buyers check first

CAS number
106560-14-9
Formula
C12H15NO5S
Molar mass
285.32 g/mol
HS code
293499
Category
Heterocyclic building blocks

What is Faropenem?

Plain description, key identifiers and synonyms

6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid is a faropenem. It is a conjugate acid of a 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CAS number
106560-14-9 CAS number cross-checked
Molecular formula
C12H15NO5S
UNII
F52Y83BGH3
InChIKey
HGGAKXAHAYOLDJ-FHZUQPTBSA-N
InChI
InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1
Canonical SMILES
CC(O)C1C(=O)N2C(C(=O)O)=C(C3CCCO3)SC12
Isomeric SMILES
C[C@H]([C@@H]1[C@@H]2N(C1=O)C(=C(S2)[C@H]3CCCO3)C(=O)O)O

Synonyms

  • Fropenem
  • (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (+)-(5R,6S)-6-((1R)-1-Hydroxyethyl)-7-oxo-3-((2R)-tetrahydro-2-furyl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • (5R,6S)-6-((1R)-1-Hydroxyethyl)-7-oxo-3-((2R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • faropenemum
  • (5R,6S)-6-((1R)-1-hydroxyethyl)-7-oxo-3-((2R)-oxolan-2-yl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • faropenem medoxil\nfaropenem medoxil
  • (5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-hydroxyethylpenem-3-carboxylate
  • 6alpha-[(1R)-1-hydroxyethyl]-2-[(2R)-tetrahydrofuran-2-yl]-2,3-didehydropenam-3-carboxylic acid
  • 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid
  • (5R,6S)-6-((R)-1-Hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5r,6s)-6-(1-Hydroxyethyl)-7-Oxo-3-[(2r)-Oxolan-2-Yl]-4-Thia-1-Azabicyclo[3.2.0]hept-2-Ene-2-Carboxylic Acid
  • 122547-49-3 (Na)
  • compound 1
  • 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-((1R)-1-hydroxyethyl)-7-oxo-3-((2R)-tetrahydro-2-furanyl)-,(5R,6S)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
285.32 g/molcalc.
Exact mass
285.0671 Dacalc.
LogP (octanol/water)
0.37calc.
Topological polar surface area
87.07 ร…ยฒcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
3calc.
Heavy atoms
19calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC2SC(C3CCCO3)=CN12

O=C1CC2SC(C3CCCO3)=CN12

3 rings, 13 atoms.

12 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Faropenem suppliers

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All 4 suppliers
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Where suppliers are based

4 suppliers in 2 countries

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Faropenem price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacology

Faropenem is a penem with a tetrahydrofuran substituent at position C2, with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes. Compared with imipenem, faropenem has improved chemical stability and reduced central nervous system effects. In addition, faropenem is resistant to hydrolysis by many beta-lactamases.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Faropenem is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Faropenem is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Faropenem, based on the data on this page

What is Faropenem?

6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid is a faropenem. It is a conjugate acid of a 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylate.

What is the CAS number of Faropenem?

The CAS registry number of Faropenem is 106560-14-9.

What is the molecular formula and weight of Faropenem?

The molecular formula of Faropenem is C12H15NO5S and its molar mass is 285.32 g/mol.

What is Faropenem used for?

Known uses and roles of Faropenem include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Faropenem hazardous?

No GHS hazard classification for Faropenem is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Faropenem?

Faropenem is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclicโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Faropenem?

CompoundList lists 4 suppliers of Faropenem in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Faropenem?

Suppliers quote Faropenem on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Faropenem

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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