CompoundList
Sign in
Insecticides and acaricides

Fenamiphos

Also known as Phenamiphos, Nemacur, Nemacur P

CAS 22224-92-6Formula C13H22NO3PSMolar mass 303.36 g/molEC 244-848-1
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Hazardous to the environment Controlled, licensed buyers only
Request as a licensed buyer Safety data
Fenamiphos chemical structure, C13H22NO3PS, CAS 22224-92-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless crystals
Melting point
49 °C
Boiling point
450 °C
Density
1.15 g/cm³ at 15 °C
Solubility
In water, 400 mg/L at 20 °C
HS code
293090
Category
Insecticides and acaricides
UN number
UN 2783

What is Fenamiphos?

Plain description, key identifiers and synonyms

Fenamiphos is an organophosphate insecticide, a phosphoramidate ester and an organophosphate nematicide. It has a role as an acaricide, an agrochemical and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is functionally related to a 4-(methylsulfanyl)-m-cresol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine
CAS number
22224-92-6 CAS number cross-checked
EC number
244-848-1
Molecular formula
C13H22NO3PS
UNII
H4NO3L2HBE
MDL number
MFCD00055454
InChIKey
ZCJPOPBZHLUFHF-UHFFFAOYSA-N
InChI
InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)
SMILES (canonical and isomeric)
CCOP(=O)(NC(C)C)OC1=CC(=C(C=C1)SC)C

Synonyms

  • Phenamiphos
  • Nemacur
  • Nemacur P
  • Methaphenamiphos
  • BAY sra 3886
  • BAY 68138
  • Ethyl 4-(methylthio)-m-tolyl isopropylphosphoramidate
  • Bayer 68138
  • SRA 3886
  • ENT 27572
  • Ethyl 3-methyl-4-(methylthio)phenyl (1-methylethyl)phosphoramidate
  • Isopropylamino-O-ethyl-(4-methylmercapto-3-methylphenyl)phosphate
  • Phosphoramidic acid, (1-methylethyl)-, ethyl 3-methyl-4-(methylthio)phenyl ester
  • Ethyl 3-methyl-4-(methylthio)phenyl isopropylphosphoramidate
  • 1-(Methylethyl)-ethyl 3-methyl-4-(methylthio)phenyl phosphoramidate
  • Phosphoramidic acid, isopropyl-, ethyl 4-(methylthio)-m-tolyl ester
  • Nemacur (bayer cropsci.)
  • Phosphoramidic acid, isopropyl-, 4-(methylthio)-m-tolyl ethyl ester
  • O-Aethyl-O-(3-methyl-4-methylthiophenyl)-isopropylamido-phosphorsaeureester
  • ethyl 4-(methylthio)m-tolyl isopropylphosphoroamidate
  • Ethyl-4-(methylthio)-m-tolyl isopropylphosphoramidate
  • N-(1-Methylethyl)phosphoramidic Acid Ethyl 3-Methyl-4-(methylthio)phenyl Ester
  • {ethoxy[3-methyl-4-(methylsulfanyl)phenoxy]phosphoryl}(propan-2-yl)amine
  • (ethoxy(3-methyl-4-(methylsulfanyl)phenoxy)phosphoryl)(propan-2-yl)amine
  • ethyl 3-methyl-4-(methylthio)phenyl(1-methylethyl)phosphoramidate
Show all 35 synonyms
  • ethyl-3-methyl-4-(methylthio)phenyl(1-methylethyl)phosphoramidate
  • Ethyl 3-methyl-4-(methylthio)phenyl-(1-methylethyl)phosphoramidate
  • Fenamiphos 90%
  • N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine
  • m-Cresol, 4-(methylthio)-, ethyl isopropylphosphoramidate
  • ethyl 3-methyl-4-(methylsulfanyl)phenyl N-(propan-2-yl)phosphoramidate
  • Phenamiphos [ISO-French]
  • Fenamiphos 90per cent
  • Phenamifos sulfoxide
  • Isopropylphosphoramidic Acid Ethyl 4-(Methylthio)-m-tolyl Ester

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless crystalsexp.
Melting point
49 °Cexp.
Boiling point
450 °Cexp.
Density
1.15 g/cm³ at 15 °Cexp.
Solubility
In water, 400 mg/L at 20 °Cexp.
Vapour pressure
9.0 × 10⁻⁶ mm Hg at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
303.36 g/molcalc.
Exact mass
303.1058 Dacalc.
LogP (octanol/water)
4.24calc.
Topological polar surface area
47.56 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
7calc.
Heavy atoms
19calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.54calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H319Causes serious eye irritation.
  • H330Fatal if inhaled.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (23)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2783
Transport hazard class
6.1
Packing group
I

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Fenamiphos suppliers

Controlled substance, listings of documented suppliers only, in the documented ranking

Pesticide toxic

Fenamiphos is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Fenamiphos

Reference: Highly hazardous pesticide, WHO class Ia or Ib

Our policy on controlled substances
No documented supplier lists it yet

Licensed buyers can post a request for Fenamiphos with their licence. Our compliance team reviews it before suppliers see it.

Request as a licensed buyer

Fenamiphos price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Classified for restricted use and limited to use by or under the direct supervision of a certified applicator. Formulation: Emulsifiable concentrate 35% and greater, Use Pattern: All uses, Classification: Restricted, Criteria Influencing Restriction: Acute dermal toxicity.

Nematicide for use on a wide variety of field, vegetable and fruit crops. Nematicidal activity against endoparasitic, ectoparasitic, cyst forming and root knotting species ...

Controls nematodes in field, vegetable, fruit, turf, and ornamental crops.

The majority of labeled uses are for plant parasitic nematodes and thrips. Additional pests include aphids, cutworms, citrus root weevil, flea beetles, Fuller rose beetle, mole crickets, phylloxera, and wireworms.

Read more

.../Use sites: / Apple, asparagus, banana, beets (garden), bok choy, Brussels sprouts, cabbage, cherries, citrus (except on kumquat, tangelo, or citrus hybrids in California), eggplant, garlic, grapes, kiwifruit, nectarine, okra, peaches, peanuts, peppers (nonbell), pineapples, raisins, raspberries, strawberries. ...Commercial, industrial, and ornamental turf, sod farm, golf course turf, ornamental and shade trees, tobacco, and the following ornamental plants: herbaceous plants, nonflowering plants, woody shrubs and vines, and other nonbearing crops.

Pharmacological actions

  • Pesticides

Roles

  • acaricide
  • agrochemical
  • enzyme inhibitor
  • pesticide

Functional uses

  • Biocide

Pharmacology

Fenamiphos is a synthetic phosphoramidate ester compound and organophosphate acetylcholinesterase inhibitor and neurotoxicant that is used as a pesticide. It is characterized as a highly toxic colorless or brown waxy solid, and exposure occurs by inhalation, ingestion, or contact.

How it is made

React 4-methylthio-m-cresol with ethylisopropylamidophosphorochloride.

Fenamiphos is prepared by condensing 4-methylthio-m-cresol with O-ethyl N-isopropyl phosphoramidochloride, or with ethyl dichlorophosphate followed by reaction with isopropylamine.

3-Methyl-4-(methylmercapto)phenol + phosphorus oxychloride + ethanol + isopropylamine (dehydrochlorination/dehydrochlorination/dehydrochlorination)

Regulatory status

Inventories, regulations and trade controls that list this substance

Pesticide toxic

Fenamiphos is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Fenamiphos

Reference: Highly hazardous pesticide, WHO class Ia or Ib

Our policy on controlled substances

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 015-123-00-5

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Fenamiphos is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Fenamiphos is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Fenamiphos, based on the data on this page

What is Fenamiphos?

Fenamiphos is an organophosphate insecticide, a phosphoramidate ester and an organophosphate nematicide. It has a role as an acaricide, an agrochemical and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is functionally related to a 4-(methylsulfanyl)-m-cresol.

What is the CAS number of Fenamiphos?

The CAS registry number of Fenamiphos is 22224-92-6.

What is the molecular formula and weight of Fenamiphos?

The molecular formula of Fenamiphos is C13H22NO3PS and its molar mass is 303.36 g/mol.

What is Fenamiphos used for?

Classified for restricted use and limited to use by or under the direct supervision of a certified applicator. Formulation: Emulsifiable concentrate 35% and greater, Use Pattern: All uses, Classification: Restricted, Criteria Influencing Restriction: Acute dermal toxicity.

Is Fenamiphos hazardous?

Fenamiphos carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Fenamiphos?

Fenamiphos is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Can I buy Fenamiphos on CompoundList?

Fenamiphos is a controlled substance. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed by our compliance team before suppliers see it.

Guides for buyers

Practical guides that help when you source, ship or handle Fenamiphos

Request as a licensed buyer

Upload your licence with the request. Our compliance team reviews it before the documented suppliers see it.
Request as a licensed buyer
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Fenamiphos with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/fenamiphos-22224-92-6" title="Fenamiphos structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Insecticides and acaricides or HS code 293090

Price on request
Free quotes, contact stays private
Licensed request