Fentanyl safety data
Fentanyl is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.
Listing and enquiries are not allowed for this substance.
Reference: UN Single Convention on Narcotic Drugs 1961
Our policy on controlled substancesGHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
GHS classification
Pictograms, signal word and hazard classes of the GHS classification
Hazard classes and categories
- Acute Tox. 1/2 (oral)
- Acute Tox. 1/2 (dermal)
- Skin Sens. 1
- Acute Tox. 1/2 (inhalation)
- Resp. Sens. 1
- Repr. 2
- Lact.
- Aquatic Chronic 4
Hazard statements
H codes grouped by type. Percentages show the share of classification notifications that report the statement
Health hazards
- H300Fatal if swallowed.
- H310Fatal in contact with skin.
- H317May cause an allergic skin reaction.
- H330Fatal if inhaled.
- H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H361Suspected of damaging fertility or the unborn child.
- H362May cause harm to breast-fed children.
Environmental hazards
- H413May cause long lasting harmful effects to aquatic life.
Precautionary statements
P codes for prevention, response, storage and disposal
Prevention
- P203Obtain, read and follow all safety instructions before use.
- P233Keep container tightly closed.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P262Do not get in eyes, on skin, or on clothing.
- P263Avoid contact during pregnancy and while nursing.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P273Avoid release to the environment.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P284In case of inadequate ventilation wear respiratory protection.
Response
- P301 + P316If swallowed: Get emergency medical help immediately.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P316Get emergency medical help immediately.
- P318If exposed or concerned, get medical advice.
- P320Specific treatment is urgent (see supplemental first aid instructions on the label).
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
- P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
Storage
- P403Store in a well-ventilated place.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
Disposal
- P501Dispose of contents and container in accordance with local regulations.
Handling, storage and disposal
Summaries only, follow the supplier SDS for your grade
Safe handling
GENERAL INFORMATION First Responders should use a NIOSH-certified Chemical, Biological, Radiological, Nuclear (CBRN) Self Contained Breathing Apparatus (SCBA) with a Level A protective suit when entering an area with an unknown contaminant or when entering an area where the concentration of the contaminant is unknown. Level A protection should be used until monitoring results confirm the contaminant and the concentration of the contaminant.NOTE:Safe use of protective clothing and equipment requires specific skills developed through training and experience. LEVEL A: (RED ZONE) Select when the greatest level of skin, respiratory, and eye protection is required. This is the maximum protection for workers in danger of exposure to unknown chemical hazards or levels above the IDLH or greater than the AEGL-2.
Disposal
SRP: Expired or waste pharmaceuticals shall carefully take into consideration applicable DEA, EPA, and FDA regulations. It is not appropriate to dispose by flushing the pharmaceutical down the toilet or discarding to trash. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.
Exposure limits and toxicity
Occupational exposure limits and toxicity data
Introduced into clinical practice in the 1960s, the analgesic fentanyl is 100 times more potent than morphine. Various methods of administration exist including the transdermal patch system, widely used in chronic pain and palliative care settings. Numerous, often imaginative methods of abuse of fentanyl patches have been reported, the majority of fatal fentanyl overdose cases resulting from deliberate abuse or suicide. The most serious adverse effect of fentanyl is respiratory depression. Fentanyl should be administered only under the supervision of qualified clinicians. Patients receiving fentanyl should be advised of the importance of taking the drug exactly as prescribed.
Supplier safety data sheets
SDS documents uploaded by suppliers who list this chemical
No supplier has uploaded an SDS for Fentanyl yet.
Safety questions
Quick answers about handling Fentanyl safely
Is Fentanyl hazardous?
Which GHS pictograms apply to Fentanyl?
Where can I get the SDS for Fentanyl?
GHS classification summary, not an SDS. Always check the supplier's SDS. Last updated 7 Oct 2026. Report an error