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Analgesics and anti-inflammatories

Firocoxib

Also known as Equioxx, Previcox, Librens

CAS 189954-96-9Formula C17H20O5SMolar mass 336.41 g/molEC 837-109-5
GHS signal word: Danger. Pictograms: Serious health hazard 40 suppliers listed Drug substance
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Firocoxib chemical structure, C17H20O5S, CAS 189954-96-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
189954-96-9
Formula
C17H20O5S
Molar mass
336.41 g/mol
EC number
837-109-5
HS code
293220
Category
Analgesics and anti-inflammatories

What is Firocoxib?

Plain description, key identifiers and synonyms

Firocoxib is an enol ether that is the cyclopropylmethyl ether of 3-hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2-one. A selective cyclooxygenase 2 inhibitor, it is used in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in horses and dogs. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antineoplastic agent and a cyclooxygenase 2 inhibitor. It is a sulfone, an enol ether, a butenolide and a member of cyclopropanes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
CAS number
189954-96-9 CAS number cross-checked
EC number
837-109-5
Molecular formula
C17H20O5S
UNII
Y6V2W4S4WT
MDL number
MFCD09837800
InChIKey
FULAPETWGIGNMT-UHFFFAOYSA-N
InChI
InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3
SMILES (canonical and isomeric)
CC1(C(=C(C(=O)O1)OCC2CC2)C3=CC=C(C=C3)S(=O)(=O)C)C

Synonyms

  • Equioxx
  • Previcox
  • Librens
  • 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one
  • ML 1785713
  • firocoxibum
  • ML-1,785,713
  • Firocoxib (ema epar: veterinary)
  • 2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-
  • 3-(Cyclopropylmethoxy)-4-(4-methylsulfonylphenyl)-5,5-dimethylfuranone
  • 3-(cyclopropylmethoxy)-4-(4-methanesulfonylphenyl)-5,5-dimethyl-2,5-dihydrofuran-2-one
  • 2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)-
  • 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one
  • Firovet
  • Flexira
  • EquiCoxib
  • Firox
  • OstiCoxib
  • Equioxx Injection
  • Firocoxib for Dogs
  • Equioxx Oral Paste
  • Firocoxib for Horses
  • Firocoxib Tablets for Horses
  • Firocoxib Chewable Tablets for Dogs
  • ML1,785,713
Show all 33 synonyms
  • Previcox Chewable Tablets
  • Equixx
  • 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
  • 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
  • 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2- one
  • Firocoxib (Standard)
  • Firocoxib (USAN/INN)
  • Equioxx (TN) [veterinary]

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
336.41 g/molcalc.
Exact mass
336.1031 Dacalc.
LogP (octanol/water)
2.56calc.
Topological polar surface area
69.67 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
5calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.47calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1OCC(c2ccccc2)=C1OCC1CC1

O=C1OCC(c2ccccc2)=C1OCC1CC1

3 rings, 17 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360May damage fertility or the unborn child.
  • H360DMay damage the unborn child.
  • H361Suspected of damaging fertility or the unborn child.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (8)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Firocoxib suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 40 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

40 suppliers in 7 countries

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Firocoxib price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antineoplastic agent
  • antirheumatic drug
  • cyclooxygenase 2 inhibitor
  • enzyme inhibitor
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Firocoxib is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Firocoxib is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Firocoxib, based on the data on this page

What is Firocoxib?

Firocoxib is an enol ether that is the cyclopropylmethyl ether of 3-hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2-one. A selective cyclooxygenase 2 inhibitor, it is used in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in horses and dogs.

What is the CAS number of Firocoxib?

The CAS registry number of Firocoxib is 189954-96-9.

What is the molecular formula and weight of Firocoxib?

The molecular formula of Firocoxib is C17H20O5S and its molar mass is 336.41 g/mol.

What is Firocoxib used for?

Use classes: Animal Drugs.

Is Firocoxib hazardous?

Firocoxib carries the GHS signal word "Danger". Main hazards: may damage fertility or the unborn child, may damage the unborn child, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Firocoxib?

Firocoxib is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Firocoxib?

CompoundList lists 40 suppliers of Firocoxib in China, United States, Germany, India and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Firocoxib in India?

2 suppliers in India list Firocoxib on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Firocoxib?

Suppliers quote Firocoxib on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Firocoxib

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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