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Oncology and immunology drugs

Floxuridine

Also known as 5-Fluorodeoxyuridine, 2'-Deoxy-5-fluorouridine, Fluorodeoxyuridine

CAS 50-91-9Formula C9H11FN2O5Molar mass 246.19 g/molEC 200-072-5
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard 84 suppliers listed Drug substance
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Floxuridine chemical structure, C9H11FN2O5, CAS 50-91-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from butyl acetate
Melting point
150 to 151
Solubility
1 g in about 4.5 ml isopropanol, about 7.5 ml methanol, about 12 ml alcohol, about 27 ml…
HS code
293499
Category
Oncology and immunology drugs
UN number
UN 1760
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Floxuridine?

Plain description, key identifiers and synonyms

Floxuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase, used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. It has a role as a radiosensitizing agent, an antimetabolite, an antineoplastic agent and an antiviral drug. It is a pyrimidine 2'-deoxyribonucleoside, an organofluorine compound and a nucleoside analogue.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
CAS number
50-91-9 CAS number cross-checkedOther or deprecated CAS: 136353-77-0
EC number
200-072-5
Molecular formula
C9H11FN2O5
UNII
039LU44I5M
MDL number
MFCD00006530
InChIKey
ODKNJVUHOIMIIZ-RRKCRQDMSA-N
InChI
InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
Canonical SMILES
O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1F
Isomeric SMILES
C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O

Synonyms

  • 5-Fluorodeoxyuridine
  • 2'-Deoxy-5-fluorouridine
  • Fluorodeoxyuridine
  • FUDR
  • Fluoruridine deoxyribose
  • 5FdU
  • FdUrd
  • Floxuridin
  • Deoxyfluorouridine
  • FDUR
  • 5-Fluoro-2-desoxyuridine
  • Floxuridinum
  • Floxiridina
  • 5 Fluorodeoxyuridine
  • 5-Fluoro-2-deoxyuridine
  • 5-Fluorouracil 2'-deoxyriboside
  • beta-5-Fluoro-2'-deoxyuridine
  • Uridine, 2'-deoxy-5-fluoro-
  • 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
  • 5-FUDR
  • 5-Fluorouracil deoxyriboside
  • floxuridina
  • 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  • 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  • 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Show all 36 synonyms
  • 5-Fluoro-2'-deoxy-beta-uridine
  • 5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • Fluorouridine Deoxyribose
  • F.u.d.r.
  • 2-Deoxy-5-fluorouridine
  • 5-Fluorouridine Deoxyribose
  • 5-fluoro-1-((2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1h,3h)-dione
  • 5-FdUrd
  • 2'-deoxy-5-fluoro-d-uridine
  • 5-24-06-00291 (Beilstein Handbook Reference)
  • Uridine, 2'-deoxy-5'-fluoro-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from butyl acetateexp.
Odour
ODORLESSexp.
Melting point
150 to 151exp.
Solubility
1 g in about 4.5 ml isopropanol, about 7.5 ml methanol, about 12 ml alcohol, about 27 ml acetone, insol in chloroform, ether, and benzeneexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
246.19 g/molcalc.
Exact mass
246.0652 Dacalc.
LogP (octanol/water)
-1.68calc.
Topological polar surface area
104.6 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
2calc.
Heavy atoms
17calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.56calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1ccn(C2CCCO2)c(=O)[nH]1

O=c1ccn(C2CCCO2)c(=O)[nH]1

2 rings, 13 atoms, the Tetrahydrofuryluracil ring system.

3,051 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H341Suspected of causing genetic defects.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1760

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Floxuridine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 84 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

84 suppliers in 13 countries

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Floxuridine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Antiviral, antineoplastic.

Pharmacological actions

  • Antimetabolites, Antineoplastic

Roles

  • antiinfective agent
  • antimetabolite
  • antimicrobial agent
  • antimicrobial drug
  • antineoplastic agent
  • antiviral agent
  • antiviral drug
  • pharmaceutical
  • radiosensitizing agent

Pharmacology

Floxuridine is an Antimetabolite.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Floxuridine is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Floxuridine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Floxuridine, based on the data on this page

What is Floxuridine?

Floxuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase, used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

What is the CAS number of Floxuridine?

The CAS registry number of Floxuridine is 50-91-9. Other or deprecated CAS numbers: 136353-77-0.

What is the molecular formula and weight of Floxuridine?

The molecular formula of Floxuridine is C9H11FN2O5 and its molar mass is 246.19 g/mol.

What is Floxuridine used for?

Therapeutic category: Antiviral, antineoplastic.

Is Floxuridine hazardous?

Floxuridine carries the GHS signal word "Danger". Main hazards: toxic if swallowed, suspected of causing genetic defects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Floxuridine?

Floxuridine is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Floxuridine?

CompoundList lists 84 suppliers of Floxuridine in China, United States, Germany, United Kingdom and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Floxuridine?

Suppliers quote Floxuridine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Floxuridine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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