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Analgesics and anti-inflammatories

Flunisolide

Also known as Aerobid, Syntaris, Flunisolide anhydrous

CAS 3385-03-3Formula C24H31FO6Molar mass 434.50 g/molEC 222-193-2
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 40 suppliers listed Drug substance
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Flunisolide chemical structure, C24H31FO6, CAS 3385-03-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
3385-03-3
Formula
C24H31FO6
Molar mass
434.50 g/mol
EC number
222-193-2
HS code
293299
Category
Analgesics and anti-inflammatories

What is Flunisolide?

Plain description, key identifiers and synonyms

Flunisolide is a primary alpha-hydroxy ketone, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a fluorinated steroid, a cyclic ketal and a 3-oxo-Delta(1),Delta(4)-steroid. It has a role as an anti-inflammatory drug, an immunosuppressive agent and an anti-asthmatic drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
CAS number
3385-03-3 CAS number cross-checkedOther or deprecated CAS: 77326-96-6
EC numbers
222-193-2, 680-658-9
Molecular formula
C24H31FO6
UNII
78M02AA8KF
MDL number
MFCD00133324
InChIKey
XSFJVAJPIHIPKU-XWCQMRHXSA-N
InChI
InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
Canonical SMILES
CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(C(=O)CO)O1
Isomeric SMILES
C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@]35C)F)O

Synonyms

  • Aerobid
  • Syntaris
  • Flunisolide anhydrous
  • Flunisolida
  • Nasalide
  • Nasarel
  • Aerospan
  • Flunisolidum
  • Aerospan HFA
  • Flunisolide Hemihydrate
  • Syntaris Hayfever
  • 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16, 17-acetal with acetone
  • Pregna-1,4-diene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-
  • flunisolide hemihydrate, (6alpha,11beta,16alpha)-
  • 6 alpha-fluorodihydroxy-16 alpha,17 alpha-isopropylidenedioxy-1,4-pregnadiene-3,20-dione
  • Bronalide
  • Flunisolide HFA
  • Synaclyn
  • Lunis
  • Rhinalar
  • Nisolid
  • Soluzione
  • Aerobid M
  • Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(6a,11b,16a)-
  • (6alpha,11beta,16alpha)-6-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
Show all 28 synonyms
  • Flunisolide [anhydrous]
  • lunisolide anhydrous
  • RS 3999

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
434.50 g/molcalc.
Exact mass
434.2105 Dacalc.
LogP (octanol/water)
2.27calc.
Topological polar surface area
93.06 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
2calc.
Heavy atoms
31calc.
Rings
5calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.75calc.
Formal charge
0calc.
Stereocentres
9calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OCOC12

O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OCOC12

5 rings, 21 atoms.

180 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Flunisolide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 40 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

40 suppliers in 11 countries

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Flunisolide price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Asthmatic Agents
  • Anti-Inflammatory Agents

Roles

  • anti-allergic agent
  • anti-asthmatic agent
  • anti-asthmatic drug
  • anti-inflammatory agent
  • anti-inflammatory drug
  • immunomodulator
  • immunosuppressive agent
  • nasal decongestant
  • pharmaceutical

Pharmacology

Flunisolide anhydrous is a Corticosteroid. The mechanism of action of flunisolide anhydrous is as a Corticosteroid Hormone Receptor Agonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Flunisolide is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Flunisolide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Flunisolide, based on the data on this page

What is Flunisolide?

Flunisolide is a primary alpha-hydroxy ketone, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a fluorinated steroid, a cyclic ketal and a 3-oxo-Delta(1),Delta(4)-steroid. It has a role as an anti-inflammatory drug, an immunosuppressive agent and an anti-asthmatic drug.

What is the CAS number of Flunisolide?

The CAS registry number of Flunisolide is 3385-03-3. Other or deprecated CAS numbers: 77326-96-6.

What is the molecular formula and weight of Flunisolide?

The molecular formula of Flunisolide is C24H31FO6 and its molar mass is 434.50 g/mol.

What is Flunisolide used for?

Use classes: Pharmaceuticals.

Is Flunisolide hazardous?

Flunisolide carries the GHS signal word "Danger". Main hazards: fatal if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Flunisolide?

Flunisolide is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Flunisolide?

CompoundList lists 40 suppliers of Flunisolide in China, United States, United Kingdom, Italy and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Flunisolide?

Suppliers quote Flunisolide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Flunisolide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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