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Murcko scaffold

Ring system with 5 rings and 21 atoms

181 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
21
Chemicals
181
With full pages
22
Scaffold SMILES

O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OCOC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OCOC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 181 chemicals

Fluocinolone acetonide chemical structure, C24H30F2O6, CAS 67-73-2
Fluocinolone acetonide
CAS 67-73-2C24H30F2O6
Triamcinolone acetonide chemical structure, C24H31FO6, CAS 76-25-5
Triamcinolone acetonide
CAS 76-25-5C24H31FO6
Fluocinonide chemical structure, C26H32F2O7, CAS 356-12-7
Fluocinonide
CAS 356-12-7C26H32F2O7
Triamcinolone acetonide 21-dihydrogen phosphate chemical structure, C24H32FO9P, CAS 989-96-8
Triamcinolone acetonide 21-dihydrogen phosphate
CAS 989-96-8C24H32FO9P
Triamcinolone acetonide sodium phosphate chemical structure, C24H30FNa2O9P, CAS 1997-15-5
Triamcinolone acetonide sodium phosphate
CAS 1997-15-5C24H30FNa2O9P
Triamcinolone hexacetonide chemical structure, C30H41FO7, CAS 5611-51-8
Triamcinolone hexacetonide
CAS 5611-51-8C30H41FO7
Dexbudesonide chemical structure, C25H34O6, CAS 51372-29-3
Dexbudesonide
CAS 51372-29-3C25H34O6
Triamcinolone acetonide 21-palmitate chemical structure, C40H61FO7, CAS 92626-27-2
Triamcinolone acetonide 21-palmitate
CAS 92626-27-2C40H61FO7
(22S)-Budesonide chemical structure, C25H34O6, CAS 51372-28-2
(22S)-Budesonide
CAS 51372-28-2C25H34O6
Flunisolide chemical structure, C24H31FO6, CAS 3385-03-3
Flunisolide
CAS 3385-03-3C24H31FO6
4-[2-(12-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH,8H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl)-2-oxoethoxy]-4-oxobutanoic acid chemical structure, C28H35FO9, CAS 82294-75-5
4-[2-(12-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH,8H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl)-2-oxoethoxy]-4-oxobutanoic acid
CAS 82294-75-5C28H35FO9
5,7-Dichloroquinolin-8-ol, (1S,2S,4S,8S,9S,11S,13S)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one chemical structure, C33H36Cl2FNO7, CAS 65415-39-6
5,7-Dichloroquinolin-8-ol, (1S,2S,4S,8S,9S,11S,13S)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
CAS 65415-39-6C33H36Cl2FNO7
Econazole nitrate mixture with triamcinolone acetonide chemical structure, C42H47Cl3FN3O10, CAS 78371-62-7
Econazole nitrate mixture with triamcinolone acetonide
CAS 78371-62-7C42H47Cl3FN3O10
(1R,2S,4R,8S,9S,12S,13R,19S)-8-Acetyl-6,6,9,13,19-pentamethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one chemical structure, C25H34O4, CAS 6697-23-0
(1R,2S,4R,8S,9S,12S,13R,19S)-8-Acetyl-6,6,9,13,19-pentamethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
CAS 6697-23-0C25H34O4
Neomycin sulfate chemical structure, C24H31FO6, CAS 1264131-86-3
Neomycin sulfate
CAS 1264131-86-3C24H31FO6
Budesonide chemical structure, C25H34O6, CAS 51333-22-3
Budesonide
CAS 51333-22-3C25H34O6
Desonide chemical structure, C24H32O6, CAS 638-94-8
Desonide
CAS 638-94-8C24H32O6
Synalar-C chemical structure, C33H35ClF2INO7, CAS 53262-68-3
Synalar-C
CAS 53262-68-3C33H35ClF2INO7
Procinonide chemical structure, C27H34F2O7, CAS 58497-00-0
Procinonide
CAS 58497-00-0C27H34F2O7
Triamcinolone acetonide 21-oic acid methyl ester chemical structure, C25H31FO7, CAS 53962-32-6
Triamcinolone acetonide 21-oic acid methyl ester
CAS 53962-32-6C25H31FO7
Itrocinonide chemical structure, C29H38F2O9, CAS 106033-96-9
Itrocinonide
CAS 106033-96-9C29H38F2O9
Triclonide chemical structure, C24H28Cl3FO4, CAS 26849-57-0
Triclonide
CAS 26849-57-0C24H28Cl3FO4
Amcinafal chemical structure, C26H35FO6, CAS 3924-70-7
Amcinafal
CAS 3924-70-7C26H35FO6
Budesonide 21-oleate chemical structure, C43H66O7, CAS 102668-87-1
Budesonide 21-oleate
CAS 102668-87-1C43H66O7