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Antibiotics and anti-infectives

Fosfomycin

Also known as phosphomycin, Phosphonomycin, Fosfocina

CAS 23155-02-4Formula C3H7O4PMolar mass 138.06 g/molEC 245-463-1
48 suppliers listed Drug substance
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Fosfomycin chemical structure, C3H7O4P, CAS 23155-02-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
23155-02-4
Formula
C3H7O4P
Molar mass
138.06 g/mol
EC number
245-463-1
HS code
294190
Category
Antibiotics and anti-infectives

What is Fosfomycin?

Plain description, key identifiers and synonyms

Fosfomycin is a phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus. It has a role as an antimicrobial agent and an EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor. It is a member of phosphonic acids and an epoxide. It is functionally related to a phosphonic acid. It is a conjugate acid of a (1R,2S)-epoxypropylphosphonate(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
CAS number
23155-02-4 CAS number cross-checkedOther or deprecated CAS: 25030-76-6, 27354-29-6
EC number
245-463-1
Molecular formula
C3H7O4P
UNII
2N81MY12TE, 45T2YN2XJ7
InChIKey
YMDXZJFXQJVXBF-STHAYSLISA-N
InChI
InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1
Canonical SMILES
CC1OC1P(=O)(O)O
Isomeric SMILES
C[C@H]1[C@H](O1)P(=O)(O)O

Synonyms

  • phosphomycin
  • Phosphonomycin
  • Fosfocina
  • Fosfomicina
  • Fosfomycine
  • [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
  • Fosfomycinum
  • Phosphonic acid, (3-methyloxiranyl)-, (2R-cis)-
  • (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid
  • (1R,2S)-epoxypropylphosphonic acid
  • (2R-cis)-(3-Methyloxiranyl)phosphonic acid
  • L-cis-1,2-epoxypropylphosphonic acid
  • ((2R,3S)-3-methyloxiran-2-yl)phosphonic acid
  • cis-(1R,2S)-epoxypropylphosphonic acid
  • 1R-cis-(1,2-epoxypropyl)phosphonic acid
  • Tromethamine, Fosfomycin
  • Fosfonomycin
  • Veramina
  • Antibiotic 833A
  • Phosphomycin disodium salt
  • Phosphonemycin
  • Phosphonic acid, (1,2-epoxypropyl)-, (1R,2S)-(-)-
  • Fosfomicin
  • Infectophos
  • 1,2-Epoxypropylphosphonic acid
Show all 28 synonyms
  • Levo-phosphonomycin
  • Fosfomycin (USAN/INN)
  • Fosfomycin (compound 1)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
138.06 g/molcalc.
Exact mass
138.0082 Dacalc.
LogP (octanol/water)
-0.09calc.
Topological polar surface area
70.06 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
8calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CO1

C1CO1

1 ring, 3 atoms, the Ethylene oxide ring system.

3,057 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Fosfomycin suppliers

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All 48 suppliers
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Where suppliers are based

48 suppliers in 16 countries

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Fosfomycin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • antibacterial agent
  • antiinfective agent
  • antimicrobial agent
  • antineoplastic agent
  • enzyme inhibitor
  • pharmaceutical

Pharmacology

Fosfomycin is a phosphoenolpyruvate analogue and a synthetic broad-spectrum antibiotic with antimicrobial and bactericidal properties. Fosfomycin binds to and inactivates the enzyme enolpyruvate transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis and bacterial cell death.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Fosfomycin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Fosfomycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Fosfomycin, based on the data on this page

What is Fosfomycin?

Fosfomycin is a phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus. It has a role as an antimicrobial agent and an EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor. It is a member of phosphonic acids and an epoxide. It is functionally related to a phosphonic acid.

What is the CAS number of Fosfomycin?

The CAS registry number of Fosfomycin is 23155-02-4. Other or deprecated CAS numbers: 25030-76-6, 27354-29-6.

What is the molecular formula and weight of Fosfomycin?

The molecular formula of Fosfomycin is C3H7O4P and its molar mass is 138.06 g/mol.

What is Fosfomycin used for?

Known uses and roles of Fosfomycin include antibacterials and antibiotics in pharmaceuticals, antibacterial agent, antiinfective agent, antimicrobial agent, antineoplastic agent and 3 more.

Is Fosfomycin hazardous?

No GHS hazard classification for Fosfomycin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Fosfomycin?

Fosfomycin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Fosfomycin?

CompoundList lists 48 suppliers of Fosfomycin in China, United States, India, Spain and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Fosfomycin in India?

10 suppliers in India list Fosfomycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Fosfomycin?

Suppliers quote Fosfomycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Fosfomycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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