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Antibiotics and anti-infectives

Gamithromycin

Also known as gamitromicina, gamithromycinum, ML-1,709,460

CAS 145435-72-9Formula C40H76N2O12Molar mass 777.05 g/molEC 604-472-4
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 15 suppliers listed Drug substance
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Gamithromycin chemical structure, C40H76N2O12, CAS 145435-72-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
145435-72-9
Formula
C40H76N2O12
Molar mass
777.05 g/mol
EC number
604-472-4
HS code
293499
Category
Antibiotics and anti-infectives

What is Gamithromycin?

Plain description, key identifiers and synonyms

Gamithromycin is a macrolide antibiotic with formula C40H76N2O12. It is used for the treatment of of bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle. The compound is also licensed in Europe for the treatment of footrot in sheep caused by Dichelobacter nodosus and Fusobacterium nodosus. It has a role as an antibacterial drug and a protein synthesis inhibitor. It is a macrolide antibiotic and a monosaccharide derivative.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one
CAS number
145435-72-9 CAS number cross-checked
EC number
604-472-4
Molecular formula
C40H76N2O12
UNII
ZE856183S0
MDL number
MFCD09954125
InChIKey
VWAMTBXLZPEDQO-UZSBJOJWSA-N
InChI
InChI=1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1
Canonical SMILES
CCCN1CC(C)C(O)C(C)(O)C(CC)OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC1C
Isomeric SMILES
CCCN1C[C@@H]([C@H]([C@]([C@H](OC(=O)[C@@H]([C@H]([C@@H]([C@H]([C@](C[C@H]1C)(C)O)O[C@H]2[C@@H]([C@H](C[C@H](O2)C)N(C)C)O)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)CC)(C)O)O)C

Synonyms

  • gamitromicina
  • gamithromycinum
  • ML-1,709,460
  • Zactran
  • Zactran (veterinary)
  • ML 1709460
  • Gamithromycin 100 |Ig/mL in Methanol
  • Gamithromycin 100 microg/mL in Methanol
  • Gamithromycin Solution in Acetonitrile, 1000ug/mL
  • Gamithromycin Solution in Acetonitrile, 100ug/mL

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
777.05 g/molcalc.
Exact mass
776.5398 Dacalc.
LogP (octanol/water)
2.68calc.
Topological polar surface area
180.1 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
14calc.
Rotatable bonds
9calc.
Heavy atoms
54calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.98calc.
Formal charge
0calc.
Stereocentres
18calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC(OC2CCCCO2)CC(OC2CCCCO2)CCCNCCCCCO1

O=C1CC(OC2CCCCO2)CC(OC2CCCCO2)CCCNCCCCCO1

3 rings, 30 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (13)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Gamithromycin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 15 suppliers
15 of 15 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

15 suppliers in 4 countries

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Gamithromycin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • enzyme inhibitor
  • pathway inhibitor
  • pharmaceutical
  • protein synthesis inhibitor

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Gamithromycin is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Gamithromycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Gamithromycin, based on the data on this page

What is Gamithromycin?

Gamithromycin is a macrolide antibiotic with formula C40H76N2O12. It is used for the treatment of of bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle.

What is the CAS number of Gamithromycin?

The CAS registry number of Gamithromycin is 145435-72-9.

What is the molecular formula and weight of Gamithromycin?

The molecular formula of Gamithromycin is C40H76N2O12 and its molar mass is 777.05 g/mol.

What is Gamithromycin used for?

Use classes: Animal Drugs.

Is Gamithromycin hazardous?

Gamithromycin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Gamithromycin?

Gamithromycin is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Gamithromycin?

CompoundList lists 15 suppliers of Gamithromycin in China, United States, Germany and Hong Kong. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Gamithromycin?

Suppliers quote Gamithromycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Gamithromycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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