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Respiratory, allergy and digestive drugs

Erythromycin

Also known as Erythromycin A, E-Mycin, Abomacetin

CAS 114-07-8Formula C37H67NO13Molar mass 733.94 g/molEC 204-040-1
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 148 suppliers listed Drug substance
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Erythromycin chemical structure, C37H67NO13, CAS 114-07-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Hydrated crystals from water
Melting point
191 °C
Solubility
WHITE OR SLIGHTLY YELLOW, CRYSTALLINE POWDER. ODORLESS OR PRACTICALLY SO. PRACTICALLY TA…
HS code
294150
Category
Respiratory, allergy and digestive drugs
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Erythromycin?

Plain description, key identifiers and synonyms

Erythromycin A is an erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is a cyclic ketone and an erythromycin. It is functionally related to an erythronolide A. It is a conjugate base of an erythromycin A(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
CAS number
114-07-8 CAS number cross-checkedOther or deprecated CAS: 215031-94-0, 7540-22-9, 82343-12-2
EC numbers
204-040-1, 616-217-4
Molecular formula
C37H67NO13
UNII
63937KV33D
MDL number
MFCD00084654
InChIKey
ULGZDMOVFRHVEP-RWJQBGPGSA-N
InChI
InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
Canonical SMILES
CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O
Isomeric SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O

Synonyms

  • Erythromycin A
  • E-Mycin
  • Abomacetin
  • Emgel
  • Erymax
  • Ilotycin
  • Eritromicina
  • Erythromycine
  • Erythromycinum
  • Robimycin
  • Eryderm
  • Erythromycin base
  • Erycette
  • Erygel
  • Sansac
  • Erythro-Statin
  • Erythra-Derm
  • Akne-Mycin
  • ERYC
  • E-Glades
  • Ery-Tab
  • E-Base
  • Stiemycin
  • R-P Mycin
  • Eryc Sprinkles
Show all 39 synonyms
  • E-Solve 2
  • Erythromast 36
  • T-Stat
  • Torlamicina
  • C-Solve-2
  • Erythrogran
  • Eryc 125
  • erythromycin-A
  • Erythroguent
  • Dotycin
  • Oftalmolosa Cusi Eritromicina
  • Staticin
  • Retcin
  • Pce (erythromycin)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Hydrated crystals from waterexp.
Odour
Odorlessexp.
Taste
Bitterexp.
Melting point
191 °Cexp.
Solubility
WHITE OR SLIGHTLY YELLOW, CRYSTALLINE POWDER. ODORLESS OR PRACTICALLY SO. PRACTICALLY TASTELESS. PKA 7. FREELY SOL IN ACETONE & CHLOROFORM, SOL IN 95% ETHANOL & BENZENE, SPARINGLY SOL IN ETHER, VERY SLIGHTLY SOL IN WATER. /Erythromycin…exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
733.94 g/molcalc.
Exact mass
733.4612 Dacalc.
LogP (octanol/water)
1.79calc.
Topological polar surface area
193.9 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
14calc.
Rotatable bonds
7calc.
Heavy atoms
51calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.95calc.
Formal charge
0calc.
Stereocentres
18calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCCOC(=O)CC(OC2CCCCO2)CC(OC2CCCCO2)CCC1

O=C1CCCCOC(=O)CC(OC2CCCCO2)CC(OC2CCCCO2)CCC1

3 rings, 30 atoms.

111 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Erythromycin suppliers

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All 148 suppliers
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Where suppliers are based

148 suppliers in 28 countries

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Erythromycin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Antibiotic.

Therapeutic category: Antibacterial (Erythromycin stearate).

Therapeutic category (veterinary): Antibacterial (Erythromycin stearate).

Use classes: Pharmaceuticals, Animal Drugs.

Pharmacological actions

  • Anti-Bacterial Agents
  • Gastrointestinal Agents
  • Protein Synthesis Inhibitors

Roles

  • bacterial metabolite
  • metabolite
  • prokaryotic metabolite

Functional uses

  • Pharmaceutical

Pharmacology

Erythromycin is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity.

How it is made

Elaborated during the growth of a strain of Streptomycees erythreus.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Erythromycin is traded under.

HS 2941.50Exact HS code

Erythromycin and its derivatives, salts thereof

World exports in 2024
$379M
−31.1% vs 2023, imports $408M
2019 to 2024
Top exporters
  1. China79.0%
  2. India * partner reported10.6%
  3. Malaysia1.7%
Top importers
  1. India * partner reported27.3%
  2. Japan9.9%
  3. Croatia6.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Erythromycin is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Erythromycin, based on the data on this page

What is Erythromycin?

Erythromycin A is an erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is a cyclic ketone and an erythromycin.

What is the CAS number of Erythromycin?

The CAS registry number of Erythromycin is 114-07-8. Other or deprecated CAS numbers: 215031-94-0, 7540-22-9, 82343-12-2.

What is the molecular formula and weight of Erythromycin?

The molecular formula of Erythromycin is C37H67NO13 and its molar mass is 733.94 g/mol.

What is Erythromycin used for?

Antibiotic. Therapeutic category: Antibacterial (Erythromycin stearate). Therapeutic category (veterinary): Antibacterial (Erythromycin stearate). Use classes: Pharmaceuticals, Animal Drugs.

Is Erythromycin hazardous?

Erythromycin carries the GHS signal word "Danger". Main hazards: may cause an allergic skin reaction, causes serious eye irritation, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Erythromycin?

Erythromycin is usually classified under HS code 294150 (Erythromycin and its derivatives, salts thereof). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Erythromycin?

CompoundList lists 148 suppliers of Erythromycin in China, India, United States, Germany and 24 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Erythromycin in India?

31 suppliers in India list Erythromycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Erythromycin?

Suppliers quote Erythromycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Erythromycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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