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Cosmetic antioxidants

Ginsenoside re

Also known as Ginsenoside B2, Panaxoside RE, ginsenoside-Re

CAS 52286-59-6Formula C48H82O18Molar mass 947.17 g/molEC 257-814-6
GHS signal word: Warning. Pictograms: Harmful or irritant 19 suppliers listed
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Ginsenoside re chemical structure, C48H82O18, CAS 52286-59-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
52286-59-6
Formula
C48H82O18
Molar mass
947.17 g/mol
EC number
257-814-6
HS code
293890
Category
Cosmetic antioxidants

What is Ginsenoside re?

Plain description, key identifiers and synonyms

Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(12)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as an antioxidant, an antineoplastic agent, a neuroprotective agent, an anti-inflammatory agent, a nephroprotective agent and a plant metabolite. It is a 3beta-hydroxy-4,4-dimethylsteroid, a beta-D-glucoside, a tetracyclic triterpenoid, a 3beta-hydroxy steroid, a 12beta-hydroxy steroid, a disaccharide derivative and a ginsenoside. It derives from a hydride of a dammarane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
CAS number
52286-59-6
EC number
257-814-6
Molecular formula
C48H82O18
UNII
46F3R0BL3I
MDL number
MFCD00133369
INCI name
GINSENOSIDE RE
InChIKey
PWAOOJDMFUQOKB-WCZZMFLVSA-N
InChI
InChI=1S/C48H82O18/c1-21(2)11-10-14-48(9,66-42-38(60)35(57)32(54)26(19-49)63-42)23-12-16-46(7)30(23)24(51)17-28-45(6)15-13-29(52)44(4,5)40(45)25(18-47(28,46)8)62-43-39(36(58)33(55)27(20-50)64-43)65-41-37(59)34(56)31(53)22(3)61-41/h11,22-43,49-60H,10,12-20H2,1-9H3/t22-,23-,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,43+,45+,46+,47+,48-/m0/s1
Canonical SMILES
CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C1CCC2(C)C1C(O)CC1C3(C)CCC(O)C(C)(C)C3C(OC3OC(CO)C(O)C(O)C3OC3OC(C)C(O)C(O)C3O)CC12C
Isomeric SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2O[C@H]3C[C@@]4([C@H](C[C@H]([C@H]5[C@]4(CC[C@@H]5[C@](C)(CCC=C(C)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)O)[C@@]7([C@@H]3C([C@H](CC7)O)(C)C)C)C)CO)O)O)O)O)O

Synonyms

  • Ginsenoside B2
  • Panaxoside RE
  • ginsenoside-Re
  • Sanchinoside Re
  • Chikusetsusaponin IVc
  • Ginsenoside Re (Standard)
  • beta-D-Glucopyranoside, (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-
  • GinsenosideRe
  • panaxsaponin Re
  • insenoside RE
  • b-D-Glucopyranoside,(3b,6a,12b)-20-(b-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-
  • Ginsenoside B2, Panaxoside Re, Sanchinoside Re
  • (20S)-ginsenoside Re
  • 20(S)-ginsenoside Re
  • Ginsenoside B2(Standard)
  • (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
  • 2-O-(6-Deoxy-alpha-L-mannopyranosyl)-(3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-beta-D-glucopyranoside
  • Chikusetsusaponin IVc, NSC 308877, Panaxoside Re, Sanchinoside Re
  • (3|?,6| cent,12|?)-20-(|?-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-| cent-L-mannopyranosyl)-|?-D-glucopyranoside
  • (3b,6a,12b)-20-(b-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside
  • (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranoside
  • 20-(beta-D-Glucopyranosyloxy)-3beta,12beta-dihydroxydammar-24-en-6alpha-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
  • 20-(beta-D-glucopyranosyloxy)-3beta,6alpha,12beta,20-trihydroxydammar-24-en-6-yl 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranoside
  • Ginsenoside re (constituent of american ginseng, asian ginseng, and tienchi ginseng)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
947.17 g/molcalc.
Exact mass
946.5501 Dacalc.
LogP (octanol/water)
-0.03calc.
Topological polar surface area
298.1 Ųcalc.
Hydrogen bond donors
12calc.
Hydrogen bond acceptors
18calc.
Rotatable bonds
12calc.
Heavy atoms
66calc.
Rings
7calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.96calc.
Formal charge
0calc.
Stereocentres
26calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OCC2CCC3C2CCC2C4CCCCC4C(OC4OCCCC4OC4CCCCO4)CC32)OC1

C1CCC(OCC2CCC3C2CCC2C4CCCCC4C(OC4OCCCC4OC4CCCCO4)CC32)OC1

7 rings, 39 atoms.

6 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ginsenoside re suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 19 suppliers
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Where suppliers are based

19 suppliers in 3 countries

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Ginsenoside re price

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name GINSENOSIDE RE(antioxidant, humectant, skin conditioning)

Roles

  • anti-inflammatory agent
  • antineoplastic agent
  • antioxidant
  • eukaryotic metabolite
  • metabolite
  • nephroprotective agent
  • neuroprotective agent
  • pharmaceutical
  • plant metabolite
  • protective agent

Cosmetic functions

  • Antioxidant
  • Humectant
  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ginsenoside re is traded under.

HS 2938.90Indicative HS code

Natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives

World exports in 2024
$1.4B
−8.3% vs 2023, imports $1.35B
2019 to 2024
Top exporters
  1. China49.2%
  2. France * partner reported8.9%
  3. Malaysia6.1%
Top importers
  1. United States22.3%
  2. India * partner reported7.8%
  3. Brazil5.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ginsenoside re is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ginsenoside re, based on the data on this page

What is Ginsenoside re?

Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(12)-beta-D-glucopyranoside and beta-D-…

What is the CAS number of Ginsenoside re?

The CAS registry number of Ginsenoside re is 52286-59-6.

What is the molecular formula and weight of Ginsenoside re?

The molecular formula of Ginsenoside re is C48H82O18 and its molar mass is 947.17 g/mol.

What is Ginsenoside re used for?

Known uses and roles of Ginsenoside re include humectants in cosmetics and personal care, antioxidants in cosmetics and personal care, skin conditioning agents in cosmetics and personal care, anti-inflammatory agent, antineoplastic agent and 10 more.

Is Ginsenoside re hazardous?

Ginsenoside re carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ginsenoside re?

Ginsenoside re is usually classified under HS code 293890 (Glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ginsenoside re?

CompoundList lists 19 suppliers of Ginsenoside re in China, United States and Germany. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ginsenoside re?

Suppliers quote Ginsenoside re on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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