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Impurities and reference standards

Ginsenoside rf

Also known as beta-D-Glucopyranoside, (3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-beta-D-glucopyranosyl-, Panaxoside RF, GinsenosideRf

CAS 52286-58-5Formula C42H72O14Molar mass 801.02 g/molEC 634-870-3
GHS signal word: Warning. Pictograms: Harmful or irritant 5 suppliers listed
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Ginsenoside rf chemical structure, C42H72O14, CAS 52286-58-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
52286-58-5
Formula
C42H72O14
Molar mass
801.02 g/mol
EC number
634-870-3
HS code
293890
Category
Impurities and reference standards

What is Ginsenoside rf?

Plain description, key identifiers and synonyms

Ginsenoside Rf is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding beta-D-glucopyranosyl-(12)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as an antineoplastic agent, an apoptosis inducer and a plant metabolite. It is a 3beta-hydroxy-4,4-dimethylsteroid, a beta-D-glucoside, a tetracyclic triterpenoid, a 3beta-hydroxy steroid, a 12beta-hydroxy steroid, a 20-hydroxy steroid, a disaccharide derivative and a ginsenoside. It derives from a hydride of a dammarane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
CAS number
52286-58-5 CAS number cross-checked
EC number
634-870-3
Molecular formula
C42H72O14
UNII
JOS8BON5YW
MDL number
MFCD00210509
InChIKey
UZIOUZHBUYLDHW-XUBRWZAZSA-N
InChI
InChI=1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,39+,40+,41+,42-/m0/s1
Canonical SMILES
CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC1C3(C)CCC(O)C(C)(C)C3C(OC3OC(CO)C(O)C(O)C3OC3OC(CO)C(O)C(O)C3O)CC12C
Isomeric SMILES
CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)O)C)O)C

Synonyms

  • beta-D-Glucopyranoside, (3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-beta-D-glucopyranosyl-
  • Panaxoside RF
  • GinsenosideRf
  • ginsenoside-rf
  • Ginsenoside- rf
  • 20(S)-ginsenoside Rf
  • Ginsenoside Rf (Standard)
  • Ginsenoside Rf, analytical standard
  • (3b,6a,12b)-3,12,20-Trihydroxydammar-24-en-6-yl-2-O-(b-D-glucopyranosyl)-b-D-glucopyranoside
  • Ginsenoside Rf, primary pharmaceutical reference standard
  • ?-D-Glucopyranoside, (3|?,6| cent,12|?)-3,12,20-trihy
  • (beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
  • beta-d-glucopyranoside, (3beta,6alpha,12.beta.)-3,12,20-trihydroxydammar-24-en-6-yl 2-o-beta-d-glucopyranosyl-
  • 3beta,12beta,20-Trihydroxydammar-24-en-6alpha-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
  • Ginsenoside rf (constituent of american ginseng, asian ginseng, and tienchi ginseng)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
801.02 g/molcalc.
Exact mass
800.4922 Dacalc.
LogP (octanol/water)
1.12calc.
Topological polar surface area
239.2 Ųcalc.
Hydrogen bond donors
10calc.
Hydrogen bond acceptors
14calc.
Rotatable bonds
10calc.
Heavy atoms
56calc.
Rings
6calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.95calc.
Formal charge
0calc.
Stereocentres
21calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OC2CCCOC2OC2CC3C4CCCC4CCC3C3CCCCC23)OC1

C1CCC(OC2CCCOC2OC2CC3C4CCCC4CCC3C3CCCCC23)OC1

6 rings, 31 atoms.

14 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ginsenoside rf suppliers

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Where suppliers are based

5 suppliers in 1 country

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Ginsenoside rf price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • apoptosis inducer
  • eukaryotic metabolite
  • metabolite
  • pharmaceutical
  • plant metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ginsenoside rf is traded under.

HS 2938.90Indicative HS code

Natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives

World exports in 2024
$1.4B
−8.3% vs 2023, imports $1.35B
2019 to 2024
Top exporters
  1. China49.2%
  2. France * partner reported8.9%
  3. Malaysia6.1%
Top importers
  1. United States22.3%
  2. India * partner reported7.8%
  3. Brazil5.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ginsenoside rf is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ginsenoside rf, based on the data on this page

What is Ginsenoside rf?

Ginsenoside Rf is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding beta-D-glucopyranosyl-(12)-beta-D-glucopyr…

What is the CAS number of Ginsenoside rf?

The CAS registry number of Ginsenoside rf is 52286-58-5.

What is the molecular formula and weight of Ginsenoside rf?

The molecular formula of Ginsenoside rf is C42H72O14 and its molar mass is 801.02 g/mol.

What is Ginsenoside rf used for?

Known uses and roles of Ginsenoside rf include antineoplastic agent, apoptosis inducer, eukaryotic metabolite, metabolite, pharmaceutical and 1 more.

Is Ginsenoside rf hazardous?

Ginsenoside rf carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ginsenoside rf?

Ginsenoside rf is usually classified under HS code 293890 (Glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ginsenoside rf?

CompoundList lists 5 suppliers of Ginsenoside rf in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ginsenoside rf?

Suppliers quote Ginsenoside rf on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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