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Glycosides and other natural products

Ginsenoside rd

Also known as Gypenoside VIII, Chikusetsusaponin fk7, 2-O-beta-D-Glucopyranosyl-(3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-beta-D-glucopyranoside

CAS 52705-93-8Formula C48H82O18Molar mass 947.17 g/molEC 258-118-5
GHS signal word: Warning. Pictograms: Harmful or irritant 9 suppliers listed
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Ginsenoside rd chemical structure, C48H82O18, CAS 52705-93-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
52705-93-8
Formula
C48H82O18
Molar mass
947.17 g/mol
EC number
258-118-5
HS code
293890
Category
Glycosides and other natural products

What is Ginsenoside rd?

Plain description, key identifiers and synonyms

Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as an anti-inflammatory drug, an immunosuppressive agent, a neuroprotective agent, an apoptosis inducer, a vulnerary and a plant metabolite. It is a beta-D-glucoside, a tetracyclic triterpenoid and a ginsenoside. It is functionally related to a (20S)-ginsenoside Rg3.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
CAS number
52705-93-8 CAS number cross-checked
EC number
258-118-5
Molecular formula
C48H82O18
UNII
WB232T95AV
INCI name
GINSENOSIDE RD
InChIKey
RLDVZILFNVRJTL-IWFVLDDISA-N
InChI
InChI=1S/C48H82O18/c1-22(2)10-9-14-48(8,66-42-39(60)36(57)33(54)26(20-50)62-42)23-11-16-47(7)31(23)24(52)18-29-45(5)15-13-30(44(3,4)28(45)12-17-46(29,47)6)64-43-40(37(58)34(55)27(21-51)63-43)65-41-38(59)35(56)32(53)25(19-49)61-41/h10,23-43,49-60H,9,11-21H2,1-8H3/t23-,24+,25+,26+,27+,28-,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,45-,46+,47+,48-/m0/s1
Canonical SMILES
CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C1CCC2(C)C1C(O)CC1C3(C)CCC(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4O)C(C)(C)C3CCC12C
Isomeric SMILES
CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C

Synonyms

  • Gypenoside VIII
  • Chikusetsusaponin fk7
  • 2-O-beta-D-Glucopyranosyl-(3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-beta-D-glucopyranoside
  • beta-D-Glucopyranoside, (3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-
  • (3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
  • Ginsenoside rd (constituent of american ginseng, asian ginseng, and tienchi ginseng)
  • ginsenoside-Rd
  • GS-Rd
  • G-Rd
  • (20S)-ginsenoside Rd
  • 20(S)-ginsenoside Rd
  • Ginsenoside Rd (Standard)
  • (GS)-Rd
  • Gypenoside VIII (Standard)
  • (20S)-3|?-[[2-O-(|?-D-Glucopyranosyl)-|?-D-glucopyranosyl]oxy]-20-(|?-D-glucopyranosyloxy)dammaran-24-ene-12|?-ol
  • (3beta,12beta,20S)-20-[(beta-D-glucopyranosyl)oxy]-3-[(beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranosyl)oxy]dammar-24-en-12-ol
  • beta-d-glucopyranoside, (3beta,12.beta.)-20-(beta-d-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-o-beta-d-glucopyranosyl-
  • 20(S)-protopanaxadiol-3-[O-beta-D-glucopyranosyl(1->2)-beta-D-glucopyranoside]-20-(O-beta-D-glucopyranoside)
  • 20-(beta-D-glucopyranosyloxy)-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
  • 3-O-(beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranosyl)-20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol
  • beta-D-Glucopyranoside, (3-beta,12-beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
947.17 g/molcalc.
Exact mass
946.5501 Dacalc.
LogP (octanol/water)
-0.03calc.
Topological polar surface area
298.1 Ųcalc.
Hydrogen bond donors
12calc.
Hydrogen bond acceptors
18calc.
Rotatable bonds
13calc.
Heavy atoms
66calc.
Rings
7calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.96calc.
Formal charge
0calc.
Stereocentres
25calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OCC2CCC3C2CCC2C4CCC(OC5OCCCC5OC5CCCCO5)CC4CCC32)OC1

C1CCC(OCC2CCC3C2CCC2C4CCC(OC5OCCCC5OC5CCCCO5)CC4CCC32)OC1

7 rings, 39 atoms.

25 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ginsenoside rd suppliers

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Where suppliers are based

9 suppliers in 3 countries

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Ginsenoside rd price

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name GINSENOSIDE RD(antioxidant)

Roles

  • anti-inflammatory agent
  • anti-inflammatory drug
  • apoptosis inducer
  • eukaryotic metabolite
  • immunomodulator
  • immunosuppressive agent
  • metabolite
  • neuroprotective agent
  • pharmaceutical
  • plant metabolite
  • protective agent
  • vulnerary

Functional uses

  • Antioxidant

Cosmetic functions

  • Antioxidant

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ginsenoside rd is traded under.

HS 2938.90Indicative HS code

Natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives

World exports in 2024
$1.4B
−8.3% vs 2023, imports $1.35B
2019 to 2024
Top exporters
  1. China49.2%
  2. France * partner reported8.9%
  3. Malaysia6.1%
Top importers
  1. United States22.3%
  2. India * partner reported7.8%
  3. Brazil5.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ginsenoside rd is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ginsenoside rd, based on the data on this page

What is Ginsenoside rd?

Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside.

What is the CAS number of Ginsenoside rd?

The CAS registry number of Ginsenoside rd is 52705-93-8.

What is the molecular formula and weight of Ginsenoside rd?

The molecular formula of Ginsenoside rd is C48H82O18 and its molar mass is 947.17 g/mol.

What is Ginsenoside rd used for?

Known uses and roles of Ginsenoside rd include anti-inflammatories in pharmaceuticals, antioxidants in cosmetics and personal care, anti-inflammatory agent, anti-inflammatory drug, apoptosis inducer and 10 more.

Is Ginsenoside rd hazardous?

Ginsenoside rd carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ginsenoside rd?

Ginsenoside rd is usually classified under HS code 293890 (Glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ginsenoside rd?

CompoundList lists 9 suppliers of Ginsenoside rd in China, United States and Germany. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ginsenoside rd?

Suppliers quote Ginsenoside rd on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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