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Ginsenoside Rh2

Also known as 20(S)-Ginsenoside Rh2, (20S)-ginsenoside Rh2, Ginsenoside-Rh2

Ginsenoside Rh2 chemical structure, C36H62O8, CAS 78214-33-2
2D chemical structure

Key facts

What buyers check first

CAS number
78214-33-2
Formula
C36H62O8
Molar mass
622.88 g/mol
EC number
683-236-2
HS code
293890
Category
Glycosides and other natural products

What is Ginsenoside Rh2?

Plain description, key identifiers and synonyms

(20S)-ginsenoside Rh2 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as an antineoplastic agent, a bone density conservation agent, a hepatoprotective agent, an apoptosis inducer, a plant metabolite and a cardioprotective agent. It is a beta-D-glucoside, a tetracyclic triterpenoid, a 12beta-hydroxy steroid, a 20-hydroxy steroid and a ginsenoside. It derives from a hydride of a dammarane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
CAS number
78214-33-2 CAS number cross-checkedOther or deprecated CAS: 67400-17-3
EC number
683-236-2
Molecular formula
C36H62O8
UNII
0JU44A5KWG
MDL number
MFCD00800712
InChIKey
CKUVNOCSBYYHIS-IRFFNABBSA-N
InChI
InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1
Canonical SMILES
CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC1C3(C)CCC(OC4OC(CO)C(O)C(O)C4O)C(C)(C)C3CCC12C
Isomeric SMILES
CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)C)O)C)O)C

Synonyms

  • 20(S)-Ginsenoside Rh2
  • (20S)-ginsenoside Rh2
  • Ginsenoside-Rh2
  • beta-D-Glucopyranoside, (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl
  • GinsenosideRh2
  • Ginsenoside rh2(S)
  • Ginsenoside Rh2 (Standard)
  • 12beta,20-Dihydroxydammar-24-en-3beta-yl beta-D-glucopyranoside
  • beta-d-glucopyranoside, (3beta,12.beta.)-12,20-dihydroxydammar-24-en-3-yl
  • (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-D-glucopyranoside
  • 20(S)-Ginsenoside
  • Ginsenoside Rh2, 20(s)-Ginsenoside Rh2
  • Ginsenoside 20-rh2
  • (S)-(3b,12b)-12,20-Dihydroxydammar-24-en-3-yl beta-D-glucopyranoside
  • 20(S)-Rh2
  • 20(S)-Ginsenoside Rh2(Standard)
  • Ginsenoside Rh2, analytical standard
  • 3-o-beta-d-glucopyranosyl-20(S)-protopanaxadiol
  • (3?,12?)-12,20-Dihydroxydammar-24-en-3-yl ?-D-glucopyranoside
  • 3beta-(beta-D-glucopyranosyloxy)dammar-24-ene-3beta,20beta-diol
  • b-D-Glucopyranoside, (3b,12b)-12,20-dihydroxydaMMar-24-en-3-yl

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
622.88 g/molcalc.
Exact mass
622.4445 Dacalc.
LogP (octanol/water)
4.32calc.
Topological polar surface area
139.8 ร…ยฒcalc.
Hydrogen bond donors
6calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
7calc.
Heavy atoms
44calc.
Rings
5calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.94calc.
Formal charge
0calc.
Stereocentres
15calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OC2CCC3C(CCC4C5CCCC5CCC34)C2)OC1

C1CCC(OC2CCC3C(CCC4C5CCCC5CCC34)C2)OC1

5 rings, 24 atoms.

91 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ginsenoside Rh2 suppliers

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All 14 suppliers
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Where suppliers are based

14 suppliers in 2 countries

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Ginsenoside Rh2 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • apoptosis inducer
  • bone density conservation agent
  • cardioprotective agent
  • eukaryotic metabolite
  • hepatoprotective agent
  • metabolite
  • pharmaceutical
  • plant metabolite
  • protective agent

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ginsenoside Rh2 is traded under.

HS 2938.90Indicative HS code

Natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives

World exports in 2024
$1.4B
โˆ’8.3% vs 2023, imports $1.35B
2019 to 2024
Top exporters
  1. China49.2%
  2. France * partner reported8.9%
  3. Malaysia6.1%
Top importers
  1. United States22.3%
  2. India * partner reported7.8%
  3. Brazil5.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ginsenoside Rh2 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ginsenoside Rh2, based on the data on this page

What is Ginsenoside Rh2?

(20S)-ginsenoside Rh2 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced atโ€ฆ

What is the CAS number of Ginsenoside Rh2?

The CAS registry number of Ginsenoside Rh2 is 78214-33-2. Other or deprecated CAS numbers: 67400-17-3.

What is the molecular formula and weight of Ginsenoside Rh2?

The molecular formula of Ginsenoside Rh2 is C36H62O8 and its molar mass is 622.88 g/mol.

What is Ginsenoside Rh2 used for?

Known uses and roles of Ginsenoside Rh2 include antineoplastic agent, apoptosis inducer, bone density conservation agent, cardioprotective agent, eukaryotic metabolite and 5 more.

Is Ginsenoside Rh2 hazardous?

Ginsenoside Rh2 carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ginsenoside Rh2?

Ginsenoside Rh2 is usually classified under HS code 293890 (Glycosides, natural or reproduced by synthesis, and their salts, ethers, esters andโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ginsenoside Rh2?

CompoundList lists 14 suppliers of Ginsenoside Rh2 in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ginsenoside Rh2?

Suppliers quote Ginsenoside Rh2 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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