CompoundList
Glucagon chemical structure, C153H225N43O49S, CAS 9007-92-5
2D chemical structure

Key facts

What buyers check first

CAS number
9007-92-5
Formula
C153H225N43O49S
Appearance
Fine, white or faintly colored, crystalline powder
Solubility
PRACTICALLY INSOL IN WATER
HS code
293719
Category
Hormones and steroids
Illustrative photo, off-white powder in an open kraft paper sack in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Glucagon?

Plain description, key identifiers and synonyms

Glucagon is a 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S)-3-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]-5-oxopentanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-1,4-dioxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]am...
CAS number
9007-92-5Other or deprecated CAS: 16941-32-5
EC numbers
232-708-2, 685-611-6
Molecular formula
C153H225N43O49S
UNII
76LA80IG2G
InChIKey
MASNOZXLGMXCHN-ZLPAWPGGSA-N
InChI
InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1
Canonical SMILES
CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(C)O)C(C)O)C(C)C)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)O)C(C)O
Isomeric SMILES
C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC7=CN=CN7)N)O

Synonyms

  • Glucagonum
  • Glucagone
  • Glukagon Novo
  • Glucagon, pig
  • Glucagon, porcine, for bioassay
  • Glukagon
  • Glucagon, porcine, for immunoassay
  • HG-Factor
  • His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr
  • Hyperglycemic-Glycogenolytic Factor
  • HG Factor
  • His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
  • Glucagon (1-29)
  • Proglucagon (33-61)
  • Glucagon kit
  • Gvoke Kit
  • Gvoke Kit Vial
  • Glucagon, porcine
  • Gvoke PFS
  • Hyperglycemic Glycogenolytic Factor
  • Baqsimi
  • Glucagon 1555
  • Gvoke hypopen
  • Glucag0n
  • glucagon injection, solution
Show all 38 synonyms
  • Gvoke HypoPen 1 mg Auto-Injector
  • Gvoke PFS 1 mg Pre-filled Syringe
  • Gvoke HypoPen 0.5 mg Auto-Injector
  • Gvoke PFS 0.5 mg Pre-filled Syringe
  • Glucagen Hypokit
  • Glucagon (human)
  • Glucagon Emergency Kit
  • Glucagon recombinant
  • Glucagon (swine)
  • Glucagon (1-29), bovine, human, porcine
  • Glucagon-like-immunoreactivity
  • Bovine glucagon
  • Glucagon, human

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Fine, white or faintly colored, crystalline powderexp.
Odour
PRACTICALLY ODORLESSexp.
Taste
PRACTICALLY TASTELESSexp.
Solubility
PRACTICALLY INSOL IN WATERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
3,482.80 g/molcalc.
Exact mass
3,480.6157 Dacalc.
LogP (octanol/water)
-17.94calc.
Topological polar surface area
1,539 ร…ยฒcalc.
Hydrogen bond donors
55calc.
Hydrogen bond acceptors
51calc.
Rotatable bonds
113calc.
Heavy atoms
246calc.
Rings
7calc.
Aromatic rings
7calc.
Fraction sp3 carbons
0.52calc.
Formal charge
0calc.
Stereocentres
31calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCc1cnc[nH]1)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCCc1c[nH]c2ccccc12

O=C(CCc1cnc[nH]1)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCCc1c[nH]c2ccccc12

7 rings, 141 atoms.

7 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H317May cause an allergic skin reaction.
  • H332Harmful if inhaled.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (16)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Glucagon suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 37 suppliers
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  • Italy, Vicchio (La Madonna ) ManufacturerUnclaimed profile
    GlucagonGrade, purity and minimum order on request
    Price on request
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  • SwitzerlandUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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  • United States, North Augusta ManufacturerUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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  • United States, San DiegoUnclaimed profile
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  • United States, San DiegoUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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  • United States, San DiegoUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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  • China, NanjingUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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  • Spain, BarcelonaUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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  • United States, HaywardUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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  • Germany, LorrachUnclaimed profile
    GlucagonGrade, purity and minimum order on request
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

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Glucagon price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Gastrointestinal Agents
  • Hormones

Roles

  • anti-obesity agent
  • hyperglycemic agent
  • hypoglycemic agent
  • pharmaceutical

Pharmacology

Glucagon is an Antihypoglycemic Agent and Gastrointestinal Motility Inhibitor. The physiologic effect of glucagon is by means of Increased Gluconeogenesis, and Increased Glycogenolysis, and Decreased GI Smooth Muscle Tone, and Decreased GI Motility, and Decreased Glycolysis.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Glucagon is traded under.

HS 2937.19Indicative HS code

Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives andโ€ฆ

World exports in 2024
$31.5B
+59.6% vs 2023, imports $32.6B
2019 to 2024
Top exporters
  1. Ireland57.3%
  2. United States29.0%
  3. Denmark6.3%
Top importers
  1. United States50.4%
  2. Italy28.1%
  3. Germany7.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Glucagon is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Glucagon, based on the data on this page

What is Glucagon?

Glucagon is a 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.

What is the CAS number of Glucagon?

The CAS registry number of Glucagon is 9007-92-5. Other or deprecated CAS numbers: 16941-32-5.

What is the molecular formula and weight of Glucagon?

The molecular formula of Glucagon is C153H225N43O49S and its molar mass is 3,482.80 g/mol.

What is Glucagon used for?

Known uses and roles of Glucagon include hormones and steroids in pharmaceuticals, anti-obesity agent, hyperglycemic agent, hypoglycemic agent, pharmaceutical and 2 more.

Is Glucagon hazardous?

Glucagon carries the GHS signal word "Danger". Main hazards: may cause an allergic skin reaction, harmful if inhaled, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Glucagon?

Glucagon is usually classified under HS code 293719 (Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives andโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Glucagon?

CompoundList lists 37 suppliers of Glucagon in United States, China, Spain, Canada and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Glucagon?

Suppliers quote Glucagon on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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