Glucagon
Also known as Glucagonum, Glucagone, Glukagon Novo
Key facts
What buyers check first
- CAS number
- 9007-92-5
- Formula
- C153H225N43O49S
- Appearance
- Fine, white or faintly colored, crystalline powder
- Solubility
- PRACTICALLY INSOL IN WATER
- HS code
- 293719
- Category
- Hormones and steroids

What is Glucagon?
Plain description, key identifiers and synonyms
Glucagon is a 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (3S)-3-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]-5-oxopentanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-1,4-dioxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]am...
- CAS number
- 9007-92-5Other or deprecated CAS: 16941-32-5
- EC numbers
- 232-708-2, 685-611-6
- Molecular formula
- C153H225N43O49S
- UNII
- 76LA80IG2G
- InChIKey
- MASNOZXLGMXCHN-ZLPAWPGGSA-N
- InChI
- InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1
- Canonical SMILES
- CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(C)O)C(C)O)C(C)C)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)O)C(C)O
- Isomeric SMILES
- C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC7=CN=CN7)N)O
Synonyms
- Glucagonum
- Glucagone
- Glukagon Novo
- Glucagon, pig
- Glucagon, porcine, for bioassay
- Glukagon
- Glucagon, porcine, for immunoassay
- HG-Factor
- His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr
- Hyperglycemic-Glycogenolytic Factor
- HG Factor
- His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
- Glucagon (1-29)
- Proglucagon (33-61)
- Glucagon kit
- Gvoke Kit
- Gvoke Kit Vial
- Glucagon, porcine
- Gvoke PFS
- Hyperglycemic Glycogenolytic Factor
- Baqsimi
- Glucagon 1555
- Gvoke hypopen
- Glucag0n
- glucagon injection, solution
Show all 38 synonymsShow fewer synonyms
- Gvoke HypoPen 1 mg Auto-Injector
- Gvoke PFS 1 mg Pre-filled Syringe
- Gvoke HypoPen 0.5 mg Auto-Injector
- Gvoke PFS 0.5 mg Pre-filled Syringe
- Glucagen Hypokit
- Glucagon (human)
- Glucagon Emergency Kit
- Glucagon recombinant
- Glucagon (swine)
- Glucagon (1-29), bovine, human, porcine
- Glucagon-like-immunoreactivity
- Bovine glucagon
- Glucagon, human
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Fine, white or faintly colored, crystalline powderexp.Measured value |
|---|---|
| Odour | PRACTICALLY ODORLESSexp.Measured value |
| Taste | PRACTICALLY TASTELESSexp.Measured value |
| Solubility | PRACTICALLY INSOL IN WATERexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 3,482.80 g/molcalc.Computed value |
|---|---|
| Exact mass | 3,480.6157 Dacalc.Computed value |
| LogP (octanol/water) | -17.94calc.Computed value |
| Topological polar surface area | 1,539 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 55calc.Computed value |
| Hydrogen bond acceptors | 51calc.Computed value |
| Rotatable bonds | 113calc.Computed value |
| Heavy atoms | 246calc.Computed value |
| Rings | 7calc.Computed value |
| Aromatic rings | 7calc.Computed value |
| Fraction sp3 carbons | 0.52calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 31calc.Computed value |
| Lipinski rule of five | Fails (3 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C(CCc1cnc[nH]1)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCCc1c[nH]c2ccccc12
7 rings, 141 atoms.
7 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H317May cause an allergic skin reaction.
- H332Harmful if inhaled.
- H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (16)
- P233Keep container tightly closed.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P271Use only outdoors or in a well-ventilated area.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P284In case of inadequate ventilation wear respiratory protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P317Get medical help.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403Store in a well-ventilated place.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidGlucagon suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Italy, Vicchio (La Madonna ) ManufacturerUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
- United States, North Augusta ManufacturerUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
- United States, San DiegoUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
- United States, San DiegoUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
- China, NanjingUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
- Spain, BarcelonaUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
- United States, HaywardUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
- Germany, LorrachUnclaimed profileGlucagonGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
37 suppliers in 11 countries
- United States16
- China11
- Spain2
- Canada1
- Switzerland1
- Germany1
- and 5 more countries
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Glucagon price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Gastrointestinal Agents
- Hormones
Roles
- anti-obesity agent
- hyperglycemic agent
- hypoglycemic agent
- pharmaceutical
Pharmacology
Glucagon is an Antihypoglycemic Agent and Gastrointestinal Motility Inhibitor. The physiologic effect of glucagon is by means of Increased Gluconeogenesis, and Increased Glycogenolysis, and Decreased GI Smooth Muscle Tone, and Decreased GI Motility, and Decreased Glycolysis.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Glucagon is traded under.
Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives andโฆ
- Ireland57.3%
- United States29.0%
- Denmark6.3%
- United States50.4%
- Italy28.1%
- Germany7.4%
The HS code shown for Glucagon is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Glucagon, based on the data on this page
What is Glucagon?
What is the CAS number of Glucagon?
What is the molecular formula and weight of Glucagon?
What is Glucagon used for?
Is Glucagon hazardous?
What is the HS code of Glucagon?
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What is the price of Glucagon?
Guides for buyers
Practical guides that help when you source, ship or handle Glucagon
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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