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Respiratory, allergy and digestive drugs

Teduglutide

Also known as Gattex, revestive, ALX 0600

CAS 197922-42-2Formula C164H252N44O55SMolar mass 3,752.14 g/molEC 812-261-5
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Teduglutide chemical structure, C164H252N44O55S, CAS 197922-42-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
197922-42-2
Formula
C164H252N44O55S
Molar mass
3,752.14 g/mol
EC number
812-261-5
HS code
293329
Category
Respiratory, allergy and digestive drugs

What is Teduglutide?

Plain description, key identifiers and synonyms

Teduglutide is a 33-membered polypeptide consisting of His, Gly, Asp, Gly, Ser, Phe, Ser, Asp, Glu, Met, Asn, Thr, Ile, Leu, Asp, Asn, Leu, Ala, Ala, Arg, Asp, Phe, Ile, Asn, Trp, Leu, Ile, Gln, Thr, Lys, Ile, Thr and Asp residues joined in sequence. A glucagon-like peptide-2 receptor agonist used for the treatment of short-bowel syndrome. It has a role as an antioxidant, a metabolite, a protective agent and a glucagon-like peptide-2 receptor agonist.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-6-amino-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]-4-oxobutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-methylp...
CAS number
197922-42-2 CAS number cross-checkedOther or deprecated CAS: 287714-30-1
EC number
812-261-5
Molecular formula
C164H252N44O55S
UNII
7M19191IKG
MDL number
MFCD34789752
InChIKey
CILIXQOJUNDIDU-ASQIGDHWSA-N
InChI
InChI=1S/C164H252N44O55S/c1-21-77(11)126(156(255)187-95(44-46-114(167)214)141(240)206-130(83(17)211)160(259)186-93(42-33-34-49-165)140(239)202-129(80(14)24-4)159(258)208-131(84(18)212)161(260)200-111(163(262)263)66-125(230)231)203-151(250)100(54-76(9)10)189-145(244)103(57-88-67-175-92-41-32-31-40-90(88)92)192-147(246)105(60-116(169)216)199-157(256)127(78(12)22-2)204-152(251)102(56-87-38-29-26-30-39-87)190-149(248)109(64-123(226)227)195-137(236)94(43-35-50-174-164(171)172)183-134(233)82(16)179-133(232)81(15)180-142(241)98(52-74(5)6)188-146(245)104(59-115(168)215)194-150(249)110(65-124(228)229)196-143(242)99(53-75(7)8)198-158(257)128(79(13)23-3)205-162(261)132(85(19)213)207-153(252)106(61-117(170)217)193-139(238)97(48-51-264-20)185-138(237)96(45-47-120(220)221)184-148(247)108(63-122(224)225)197-155(254)113(72-210)201-144(243)101(55-86-36-27-25-28-37-86)191-154(253)112(71-209)182-119(219)70-177-136(235)107(62-121(222)223)181-118(218)69-176-135(234)91(166)58-89-68-173-73-178-89/h25-32,36-41,67-68,73-85,91,93-113,126-132,175,209-213H,21-24,33-35,42-66,69-72,165-166H2,1-20H3,(H2,167,214)(H2,168,215)(H2,169,216)(H2,170,217)(H,173,178)(H,176,234)(H,177,235)(H,179,232)(H,180,241)(H,181,218)(H,182,219)(H,183,233)(H,184,247)(H,185,237)(H,186,259)(H,187,255)(H,188,245)(H,189,244)(H,190,248)(H,191,253)(H,192,246)(H,193,238)(H,194,249)(H,195,236)(H,196,242)(H,197,254)(H,198,257)(H,199,256)(H,200,260)(H,201,243)(H,202,239)(H,203,250)(H,204,251)(H,205,261)(H,206,240)(H,207,252)(H,208,258)(H,220,221)(H,222,223)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,262,263)(H4,171,172,174)/t77-,78-,79-,80-,81-,82-,83+,84+,85+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,126-,127-,128-,129-,130-,131-,132-/m0/s1
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CC5=CN=CN5)N

Synonyms

  • Gattex
  • revestive
  • ALX 0600
  • Gattex Kit
  • Gly(2)-GLP-2
  • Glucagon-like peptide II (2-glycine) (human)
  • teduglutidum
  • Glucagon-like Peptide II (2-glycine)
  • teduglutida
  • Teduglutide (rdna origin)
  • Teduglutide Recombinant
  • (Gly2)GLP-2
  • [Gly2]GLP-2
  • Teduglutide?
  • Hgdgsfsdemntildnlaardfinwliqtkitd
  • [2-Glycine]glucagon-like peptide II (human)
  • His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
3,752.14 g/molcalc.
Exact mass
3,749.7995 Dacalc.
LogP (octanol/water)
-16.89calc.
Topological polar surface area
1,624 Ųcalc.
Hydrogen bond donors
55calc.
Hydrogen bond acceptors
53calc.
Rotatable bonds
125calc.
Heavy atoms
264calc.
Rings
5calc.
Aromatic rings
5calc.
Fraction sp3 carbons
0.59calc.
Formal charge
0calc.
Stereocentres
38calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Teduglutide suppliers

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All 28 suppliers
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Where suppliers are based

28 suppliers in 9 countries

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Teduglutide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Gastrointestinal Agents
  • Radiation-Protective Agents

Roles

  • agonist
  • anti-HIV agent
  • anticholesteremic drug
  • antilipemic drug
  • antimicrobial agent
  • antioxidant
  • antiviral agent
  • glucagon-like peptide-2 receptor agonist
  • metabolite
  • pharmaceutical
  • protective agent
  • renoprotective agent

Pharmacology

Teduglutide is a GLP-2 Analog. The mechanism of action of teduglutide is as a Glucagon-like Peptide-2 (GLP-2) Agonist. The chemical classification of teduglutide is Glucagon-Like Peptide 2 and Analogs/Derivatives.

How it is made

Preparation: D.J. Drucker et al., World Intellectual Property Organization patent 9739031, edim, United States of America patent 5789379 (1997, 1998 both to Allelix).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Teduglutide is traded under.

HS 2933.29Indicative HS code

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…

World exports in 2024
$1.43B
−7.6% vs 2023, imports $1.47B
2019 to 2024
Top exporters
  1. China28.1%
  2. France * partner reported12.7%
  3. India * partner reported10.3%
Top importers
  1. United Kingdom13.0%
  2. United States7.9%
  3. China6.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Teduglutide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Teduglutide, based on the data on this page

What is Teduglutide?

Teduglutide is a 33-membered polypeptide consisting of His, Gly, Asp, Gly, Ser, Phe, Ser, Asp, Glu, Met, Asn, Thr, Ile, Leu, Asp, Asn, Leu, Ala, Ala, Arg, Asp, Phe, Ile, Asn, Trp, Leu, Ile, Gln, Thr, Lys, Ile, Thr and Asp residues joined in sequence.

What is the CAS number of Teduglutide?

The CAS registry number of Teduglutide is 197922-42-2. Other or deprecated CAS numbers: 287714-30-1.

What is the molecular formula and weight of Teduglutide?

The molecular formula of Teduglutide is C164H252N44O55S and its molar mass is 3,752.14 g/mol.

What is Teduglutide used for?

Known uses and roles of Teduglutide include cardiovascular drugs in pharmaceuticals, agonist, anti-hiv agent, anticholesteremic drug, antilipemic drug and 10 more.

Is Teduglutide hazardous?

No GHS hazard classification for Teduglutide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Teduglutide?

Teduglutide is usually classified under HS code 293329 (Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Teduglutide?

CompoundList lists 28 suppliers of Teduglutide in China, United States, India, Italy and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Teduglutide in India?

4 suppliers in India list Teduglutide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Teduglutide?

Suppliers quote Teduglutide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Teduglutide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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