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Gonadorelin

Also known as Gonadorelina, GnRH-I, Gonadorelinum

CAS 33515-09-2Formula C55H75N17O13Molar mass 1,182.31 g/molEC 232-895-0
GHS signal word: Danger. Pictograms: Serious health hazard 31 suppliers listed
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Gonadorelin chemical structure, C55H75N17O13, CAS 33515-09-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
33515-09-2
Formula
C55H75N17O13
Molar mass
1,182.31 g/mol
EC number
232-895-0
HS code
293719
Category
Peptides

What is Gonadorelin?

Plain description, key identifiers and synonyms

Gonadorelin is a ten-membered synthetic oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, glycyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It has a role as a gonadotropin releasing hormone agonist. It is an oligopeptide and a peptide hormone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
CAS number
33515-09-2 CAS number cross-checkedOther or deprecated CAS: 9034-40-6
EC numbers
232-895-0, 251-553-1
Molecular formula
C55H75N17O13
UNII
9O7312W37G
MDL number
MFCD00167538
InChIKey
XLXSAKCOAKORKW-AQJXLSMYSA-N
InChI
InChI=1S/C55H75N17O13/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
Canonical SMILES
CC(C)CC(NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(N)=O
Isomeric SMILES
CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6

Synonyms

  • Gonadorelina
  • GnRH-I
  • Gonadorelinum
  • Fertagyl
  • LH-Releasing factor
  • Luforan
  • Lutrefact
  • Gonadoliberin I
  • Gonadotropin-releasing factor
  • Gonadoreline
  • p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
  • Gonadorelin decapeptide
  • 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolylglycinamide
  • pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
  • Fertiral lh-rh
  • Relefact lh-rh
  • Fertelin, OvaCyst
  • Hypocrine
  • Luteostimulin
  • Relefact
  • 5-oxo-PHWSYGLRPGNH2
  • Gonadorelin for NMR identification CRS
  • Dirigestran
  • Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolyl-
  • Nialutin
Show all 38 synonyms
  • Lutal
  • Relisorm l
  • Mammalian GnRH
  • Synthetic LRF
  • Dirigestran Spofa
  • Synthetic Gn-RH
  • Mammalian LH-RH
  • Synthetic LH-RF
  • Synthetic LH-RH
  • Porchine LH-RH
  • Human LH-RH
  • Ovine LH-RH
  • LH-RH (swine)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,182.31 g/molcalc.
Exact mass
1,181.573 Dacalc.
LogP (octanol/water)
-4.39calc.
Topological polar surface area
474.6 Ųcalc.
Hydrogen bond donors
16calc.
Hydrogen bond acceptors
15calc.
Rotatable bonds
31calc.
Heavy atoms
85calc.
Rings
6calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.47calc.
Formal charge
0calc.
Stereocentres
8calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)NCC(=O)N1CCCC1

O=C(CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)NCC(=O)N1CCCC1

6 rings, 64 atoms.

81 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360May damage fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Gonadorelin suppliers

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All 31 suppliers
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Where suppliers are based

31 suppliers in 9 countries

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Gonadorelin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Roles

  • agonist
  • antineoplastic agent
  • bone density conservation agent
  • gonadotropin releasing hormone agonist
  • hormone agonist
  • hormone receptor modulator
  • pharmaceutical
  • receptor modulator

Pharmacology

Recombinant Gonadorelin is a synthetic luteinizing hormone releasing hormone (LHRH) identical to or similar to the endogenous hormone. Synthesized in and secreted by the hypothalamus, gonadorelin binds to transmembrane LHRH receptors on pituitary gonadotrophic cells, thereby stimulating synthesis and secretion of gonadotropins. Continuous administration of gonadorelin desensitizes the gonadotrophic cells, a negative feedback effect. This agent can be used in treatment of hypothalamic amenorrhea and evaluation of hypothalamic/pituitary function.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Gonadorelin is traded under.

HS 2937.19Indicative HS code

Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives and…

World exports in 2024
$31.5B
+59.6% vs 2023, imports $32.6B
2019 to 2024
Top exporters
  1. Ireland57.3%
  2. United States29.0%
  3. Denmark6.3%
Top importers
  1. United States50.4%
  2. Italy28.1%
  3. Germany7.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Gonadorelin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Gonadorelin, based on the data on this page

What is Gonadorelin?

Gonadorelin is a ten-membered synthetic oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, glycyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It has a role as a gonadotropin releasing hormone agonist. It is an oligopeptide and a peptide hormone.

What is the CAS number of Gonadorelin?

The CAS registry number of Gonadorelin is 33515-09-2. Other or deprecated CAS numbers: 9034-40-6.

What is the molecular formula and weight of Gonadorelin?

The molecular formula of Gonadorelin is C55H75N17O13 and its molar mass is 1,182.31 g/mol.

What is Gonadorelin used for?

Use classes: Animal Drugs.

Is Gonadorelin hazardous?

Gonadorelin carries the GHS signal word "Danger". Main hazards: may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Gonadorelin?

Gonadorelin is usually classified under HS code 293719 (Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Gonadorelin?

CompoundList lists 31 suppliers of Gonadorelin in United States, China, Germany, Spain and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Gonadorelin in India?

1 supplier in India list Gonadorelin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Gonadorelin?

Suppliers quote Gonadorelin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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