Triptorelin
Also known as Triptoreline, Triptorelina, Arvekap
Key facts
What buyers check first
- CAS number
- 57773-63-4
- Formula
- C64H82N18O13
- Molar mass
- 1,311.47 g/mol
- EC number
- 637-328-4
- HS code
- 293719
- Category
- Hormones and steroids
What is Triptorelin?
Plain description, key identifiers and synonyms
Triptorelin is an oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone. It has a role as an antineoplastic agent, a contraceptive drug and a gonadotropin releasing hormone agonist.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
- CAS number
- 57773-63-4 CAS number cross-checked
- EC number
- 637-328-4
- Molecular formula
- C64H82N18O13
- UNII
- 9081Y98W2V
- MDL number
- MFCD00167541
- InChIKey
- VXKHXGOKWPXYNA-PGBVPBMZSA-N
- InChI
- InChI=1S/C64H82N18O13/c1-34(2)23-46(56(88)75-45(13-7-21-69-64(66)67)63(95)82-22-8-14-52(82)62(94)72-31-53(65)85)76-58(90)48(25-36-28-70-42-11-5-3-9-40(36)42)78-57(89)47(24-35-15-17-39(84)18-16-35)77-61(93)51(32-83)81-59(91)49(26-37-29-71-43-12-6-4-10-41(37)43)79-60(92)50(27-38-30-68-33-73-38)80-55(87)44-19-20-54(86)74-44/h3-6,9-12,15-18,28-30,33-34,44-52,70-71,83-84H,7-8,13-14,19-27,31-32H2,1-2H3,(H2,65,85)(H,68,73)(H,72,94)(H,74,86)(H,75,88)(H,76,90)(H,77,93)(H,78,89)(H,79,92)(H,80,87)(H,81,91)(H4,66,67,69)/t44-,45-,46-,47-,48+,49-,50-,51-,52-/m0/s1
- Canonical SMILES
- CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(N)=O
- Isomeric SMILES
- CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8
Synonyms
- Triptoreline
- Triptorelina
- Arvekap
- Triptorelinum
- Triptodur
- (D-Trp6)-GnRH
- tryptorelin
- Decapeptyl SR
- pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
- CL 118532
- CL 118,532
- 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide
- 6-D-tryptophan-LH-RH
- Detryptoreline
- Gonapeptyl depot
- D-Trp-6-LH-RH
- LHRH, Tryptophyl(6)-
- GnRH, Trp(6)-
- LHRH, Trp(6)-
- CL-118,532
- 6-D-Tryptophanluteinizing Hormone-releasing Factor
- [D-Trp6]-LH-RH
- Trelstar depot
- Trelstar LA
- (D-Trp6)-LH-RH
Show all 32 synonymsShow fewer synonyms
- Diferelin
- D-Tryptophan-LH-RH
- Trellasar
- Moapar
- Pamorelin LA
- Triptorelin (swine)
- BIM 21003
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 1,311.47 g/molcalc.Computed value |
|---|---|
| Exact mass | 1,310.6309 Dacalc.Computed value |
| LogP (octanol/water) | -2.29calc.Computed value |
| Topological polar surface area | 490.4 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 17calc.Computed value |
| Hydrogen bond acceptors | 15calc.Computed value |
| Rotatable bonds | 33calc.Computed value |
| Heavy atoms | 95calc.Computed value |
| Rings | 8calc.Computed value |
| Aromatic rings | 6calc.Computed value |
| Fraction sp3 carbons | 0.42calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 9calc.Computed value |
| Lipinski rule of five | Fails (3 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C(CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)NCC(=O)N1CCCC1
8 rings, 74 atoms.
23 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H360May damage fertility or the unborn child.
Precautionary statements (5)
- P203Obtain, read and follow all safety instructions before use.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P318If exposed or concerned, get medical advice.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidTriptorelin suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, ShanghaiUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- China, Beijing ManufacturerUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- China, SuzhouUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- Price on request
- ChinaUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- China, Haikou City ManufacturerUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileTriptorelinGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
66 suppliers in 13 countries
- United States26
- China22
- Germany3
- Spain2
- United Kingdom2
- Hong Kong2
- and 7 more countries
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Triptorelin price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- agonist
- anti-HIV agent
- antimicrobial agent
- antineoplastic agent
- antiviral agent
- contraceptive drug
- gonadotropin releasing hormone agonist
- hormone agonist
- hormone receptor modulator
- pharmaceutical
- receptor modulator
- reproductive control drug
Pharmacology
Triptorelin is a Gonadotropin Releasing Hormone Receptor Agonist. The mechanism of action of triptorelin is as a Gonadotropin Releasing Hormone Receptor Agonist.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Triptorelin is traded under.
Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives andโฆ
- Ireland57.3%
- United States29.0%
- Denmark6.3%
- United States50.4%
- Italy28.1%
- Germany7.4%
The HS code shown for Triptorelin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Triptorelin, based on the data on this page
What is Triptorelin?
What is the CAS number of Triptorelin?
What is the molecular formula and weight of Triptorelin?
What is Triptorelin used for?
Is Triptorelin hazardous?
What is the HS code of Triptorelin?
Where can I buy Triptorelin?
Where can I buy Triptorelin in India?
What is the price of Triptorelin?
Guides for buyers
Practical guides that help when you source, ship or handle Triptorelin
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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