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Cardiovascular and metabolic drugs

Hydralazine

Also known as 1-Hydrazinylphthalazine, 1-Hydrazinophthalazine, phthalazin-1-ylhydrazine

CAS 86-54-4Formula C8H8N4Molar mass 160.18 g/molEC 201-680-3
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 65 suppliers listed Drug substance
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Hydralazine chemical structure, C8H8N4, CAS 86-54-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
86-54-4
Formula
C8H8N4
Molar mass
160.18 g/mol
EC number
201-680-3
HS code
293399
Category
Cardiovascular and metabolic drugs

What is Hydralazine?

Plain description, key identifiers and synonyms

Hydralazine is the 1-hydrazino derivative of phthalazine, a direct-acting vasodilator that is used as an antihypertensive agent. It has a role as a vasodilator agent and an antihypertensive agent. It is a member of hydrazines, a member of phthalazines, an azaarene and an ortho-fused heteroarene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
phthalazin-1-ylhydrazine
CAS number
86-54-4 CAS number cross-checkedOther or deprecated CAS: 1044569-46-1, 59275-69-3
EC number
201-680-3
Molecular formula
C8H8N4
UNII
26NAK24LS8
MDL number
MFCD00135998
InChIKey
RPTUSVTUFVMDQK-UHFFFAOYSA-N
InChI
InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)
SMILES (canonical and isomeric)
C1=CC=C2C(=C1)C=NN=C2NN

Synonyms

  • 1-Hydrazinylphthalazine
  • 1-Hydrazinophthalazine
  • phthalazin-1-ylhydrazine
  • Hypophthalin
  • Aprezolin
  • Hydralazin
  • Apresolin
  • Hidralazin
  • Hydrazinophthalazine
  • Hidralazina
  • Idralazina
  • 1(2H)-Phthalazinone, hydrazone
  • 6-Hydralazine
  • Hydrallazine
  • 1-Phthalazinylhydrazine
  • Hydralazinum
  • Phthalazine, 1-hydrazino-
  • Ciba 5968
  • Hydrazone 1(2H)-phthalazinone
  • Hidral
  • 1(2H)-Phthalazinone hydrazone
  • (2H)-Phthalazinone hydrazone
  • 5-25-17-00412 (Beilstein Handbook Reference)
  • 1-hydrazinylidene-1,2-dihydrophthalazine
  • Hydrallazin
Show all 37 synonyms
  • Hydralazine mono Hydrochloride
  • mono-Hydrochloride, Hydralazine
  • Apresoline
  • (E)-1-Hydrazono-1,2-dihydrophthalazine
  • Apressin (pharmaceutical)
  • Praparat 5968
  • Dihydralazine EP Impurity C
  • Hydralazine (INN)
  • (1Z)-1(2H)-Phthalazinone hydrazone
  • Apresolin, Apresoline, Apressin
  • phthalazinylhydrazine
  • phthalazine, 1-hydrazino-, hydrochloride

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
160.18 g/molcalc.
Exact mass
160.0749 Dacalc.
LogP (octanol/water)
0.92calc.
Topological polar surface area
63.83 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
1calc.
Heavy atoms
12calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2cnncc2c1

c1ccc2cnncc2c1

2 rings, 10 atoms, the Phthalazine ring system.

339 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301Toxic if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Hydralazine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 65 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

65 suppliers in 17 countries

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Hydralazine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Antihypertensive Agents
  • Vasodilator Agents

Roles

  • antiatherosclerotic agent
  • antihypertensive agent
  • antineoplastic agent
  • cardiovascular drug
  • hypoglycemic agent
  • pharmaceutical
  • vasodilator agent

Pharmacology

Hydralazine is an Arteriolar Vasodilator. The physiologic effect of hydralazine is by means of Arteriolar Vasodilation.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydralazine is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydralazine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydralazine, based on the data on this page

What is Hydralazine?

Hydralazine is the 1-hydrazino derivative of phthalazine, a direct-acting vasodilator that is used as an antihypertensive agent. It has a role as a vasodilator agent and an antihypertensive agent. It is a member of hydrazines, a member of phthalazines, an azaarene and an ortho-fused heteroarene.

What is the CAS number of Hydralazine?

The CAS registry number of Hydralazine is 86-54-4. Other or deprecated CAS numbers: 1044569-46-1, 59275-69-3.

What is the molecular formula and weight of Hydralazine?

The molecular formula of Hydralazine is C8H8N4 and its molar mass is 160.18 g/mol.

What is Hydralazine used for?

Use classes: Pharmaceuticals.

Is Hydralazine hazardous?

Hydralazine carries the GHS signal word "Danger". Main hazards: toxic if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Hydralazine?

Hydralazine is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydralazine?

CompoundList lists 65 suppliers of Hydralazine in China, United States, India, Spain and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Hydralazine in India?

4 suppliers in India list Hydralazine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Hydralazine?

Suppliers quote Hydralazine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydralazine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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