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Steroids and sterols

Hydroxydione

Also known as 5beta-dihydrodeoxycorticosterone, Viadryl, 21-hydroxy-5beta-pregnane-3,20-dione

CAS 303-01-5Formula C21H32O3Molar mass 332.48 g/mol
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Hydroxydione chemical structure, C21H32O3, CAS 303-01-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
303-01-5
Formula
C21H32O3
Molar mass
332.48 g/mol
HS code
291440
Category
Steroids and sterols

What is Hydroxydione?

Plain description, key identifiers and synonyms

5beta-dihydrodeoxycorticosterone is a 3-oxo-5beta-steroid formed from 11-deoxycorticosterone by reduction across the C4-C5 double bond. It has a role as a human xenobiotic metabolite. It is a primary alpha-hydroxy ketone, a 3-oxo-5beta-steroid, a 21-hydroxy steroid and a 20-oxo steroid. It is functionally related to an 11-deoxycorticosterone. It derives from a hydride of a 5beta-pregnane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(5R,8R,9S,10S,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
CAS number
303-01-5 CAS number cross-checked
Molecular formula
C21H32O3
UNII
B7VFN88375
InChIKey
USPYDUPOCUYHQL-VEVMSBRDSA-N
InChI
InChI=1S/C21H32O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h13,15-18,22H,3-12H2,1-2H3/t13-,15+,16+,17+,18-,20+,21+/m1/s1
Canonical SMILES
CC12CCC(=O)CC1CCC1C2CCC2(C)C(C(=O)CO)CCC12
Isomeric SMILES
C[C@]12CCC(=O)C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4C(=O)CO)C

Synonyms

  • 5beta-dihydrodeoxycorticosterone
  • Viadryl
  • 21-hydroxy-5beta-pregnane-3,20-dione
  • 21-Hydroxy-5 alpha-pregnane-3,20-dione
  • 5 alpha-dihydro-11-Deoxycorticosterone
  • Pregnane-3,20-dione, 21-hydroxy-, (5beta)-
  • (1S,2S,7R,10R,11S,14S,15S)-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo(8.7.0.02,?.011,1?)heptadecan-5-one
  • 21-Hydroxy-5beta-pregnan-3,20-dion
  • Hydroxydione,
  • (5R,8R,9S,10S,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
  • 21-Hydroxypregnane-3,20-dione #
  • 5b-Dihydrodeoxycorticosterone
  • 21-Hydroxypregnan-3,20-dion
  • Hydroxydione, (5 alpha)-isomer
  • 5beta-Pregnan-21-ol-3,20-dione
  • 21-Hydroxy-5b-pregnane-3,20-dione
  • (5beta)-21-hydroxypregnane-3,20-dione
  • Pregnane-3, 21-hydroxy-, (5beta)-
  • Pregnane-3,20-dione,21-hydroxy-, (5b)-
  • 21-Hydroxy-5beta-pregnan-3,20-dione, hydroxydione

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
332.48 g/molcalc.
Exact mass
332.2351 Dacalc.
LogP (octanol/water)
3.78calc.
Topological polar surface area
54.37 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
24calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.91calc.
Formal charge
0calc.
Stereocentres
7calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCC2C(CCC3C4CCCC4CCC23)C1

O=C1CCC2C(CCC3C4CCCC4CCC23)C1

4 rings, 18 atoms.

338 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Hydroxydione suppliers

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Hydroxydione price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Neurosteroids

Roles

  • animal metabolite
  • eukaryotic metabolite
  • human metabolite
  • human xenobiotic metabolite
  • mammalian metabolite
  • metabolite
  • xenobiotic metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxydione is traded under.

HS 2914.40Indicative HS code

Ketone-alcohols and ketone-aldehydes

World exports in 2024
$199M
+2.5% vs 2023, imports $247M
2019 to 2024
Top exporters
  1. China29.5%
  2. Germany14.4%
  3. Netherlands12.7%
Top importers
  1. United States37.2%
  2. Netherlands8.5%
  3. Germany6.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxydione is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxydione, based on the data on this page

What is Hydroxydione?

5beta-dihydrodeoxycorticosterone is a 3-oxo-5beta-steroid formed from 11-deoxycorticosterone by reduction across the C4-C5 double bond. It has a role as a human xenobiotic metabolite. It is a primary alpha-hydroxy ketone, a 3-oxo-5beta-steroid, a 21-hydroxy steroid and a 20-oxo steroid.

What is the CAS number of Hydroxydione?

The CAS registry number of Hydroxydione is 303-01-5.

What is the molecular formula and weight of Hydroxydione?

The molecular formula of Hydroxydione is C21H32O3 and its molar mass is 332.48 g/mol.

What is Hydroxydione used for?

Known uses and roles of Hydroxydione include animal metabolite, eukaryotic metabolite, human metabolite, human xenobiotic metabolite, mammalian metabolite and 3 more.

Is Hydroxydione hazardous?

No GHS hazard classification for Hydroxydione is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Hydroxydione?

Hydroxydione is usually classified under HS code 291440 (Ketone-alcohols and ketone-aldehydes). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxydione?

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What is the price of Hydroxydione?

Suppliers quote Hydroxydione on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxydione

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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