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Steroids and sterols

Alphaxalone

Also known as Alfaxalone, Alphaxolone, Alfaxalona

CAS 23930-19-0Formula C21H32O3Molar mass 332.48 g/molEC 636-625-6
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 24 suppliers listed Drug substance
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Alphaxalone chemical structure, C21H32O3, CAS 23930-19-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
23930-19-0
Formula
C21H32O3
Molar mass
332.48 g/mol
EC number
636-625-6
HS code
291440
Category
Steroids and sterols

What is Alphaxalone?

Plain description, key identifiers and synonyms

Alphaxolone is a corticosteroid hormone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one
CAS number
23930-19-0 CAS number cross-checked
EC number
636-625-6
Molecular formula
C21H32O3
UNII
BD07M97B2A
InChIKey
DUHUCHOQIDJXAT-OLVMNOGESA-N
InChI
InChI=1S/C21H32O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h13-17,19,23H,4-11H2,1-3H3/t13-,14+,15-,16+,17-,19+,20-,21+/m0/s1
Canonical SMILES
CC(=O)C1CCC2C3CCC4CC(O)CCC4(C)C3C(=O)CC12C
Isomeric SMILES
CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C

Synonyms

  • Alfaxalone
  • Alphaxolone
  • Alfaxalona
  • Alfaxalonum
  • Phaxan
  • 3alpha-Hydroxy-5alpha-pregnane-11,20-dione
  • GR 2/234
  • (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one
  • Alfadione
  • alfaxolone
  • delta(16)-alfaxalone
  • Alfaxan
  • Alfaxan Multidose
  • (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta(a)phenanthren-11-one
  • hydroxy-5 alpha-pregnane-11,20-dione
  • Alfaxan multidose idx
  • 5alpha-Pregnan-3alpha-ol-11,20-dione
  • Alfaxalone (INN)
  • 3-Hydroxypregnane-11,20-dione
  • Alfaxalone, Alphaxalone
  • (3a,5a)-3-Hydroxypregnane-11,20-dione
  • 3alpha-Hydroxy-5alpha-pregnan-11,20-dion
  • 5alpha-alphaxalone
  • 3-alpha-Hydroxy-5-alpha-pregnane-11,20-dione
  • (3-alpha,5-alpha)-3-Hydroxypregnane-11,20-dione
Show all 27 synonyms
  • Pregnane-11,20-dione, 3-hydroxy-, (3a,5a)-
  • 4-08-00-02091 (Beilstein Handbook Reference)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
332.48 g/molcalc.
Exact mass
332.2351 Dacalc.
LogP (octanol/water)
3.77calc.
Topological polar surface area
54.37 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
24calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.91calc.
Formal charge
0calc.
Stereocentres
8calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC2CCCC2C2CCC3CCCCC3C12

O=C1CC2CCCC2C2CCC3CCCCC3C12

4 rings, 18 atoms.

64 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301Toxic if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Alphaxalone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 24 suppliers
24 of 24 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

24 suppliers in 8 countries

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Alphaxalone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Pharmacological actions

  • Anesthetics
  • Neurosteroids

Pharmacology

Alfaxalone is a synthetic neuroactive steroid, with anesthetic activity. Upon administration, alfaxalone binds to the gamma-aminobutyric acid (GABA)-A cell surface receptor, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to modulation of neuronal cell membrane chloride ion transport and induction and maintenance of anesthesia.

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Alphaxalone is traded under.

HS 2914.40Indicative HS code

Ketone-alcohols and ketone-aldehydes

World exports in 2024
$199M
+2.5% vs 2023, imports $247M
2019 to 2024
Top exporters
  1. China29.5%
  2. Germany14.4%
  3. Netherlands12.7%
Top importers
  1. United States37.2%
  2. Netherlands8.5%
  3. Germany6.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Alphaxalone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Alphaxalone, based on the data on this page

What is Alphaxalone?

Alphaxolone is a corticosteroid hormone.

What is the CAS number of Alphaxalone?

The CAS registry number of Alphaxalone is 23930-19-0.

What is the molecular formula and weight of Alphaxalone?

The molecular formula of Alphaxalone is C21H32O3 and its molar mass is 332.48 g/mol.

What is Alphaxalone used for?

Use classes: Animal Drugs.

Is Alphaxalone hazardous?

Alphaxalone carries the GHS signal word "Danger". Main hazards: toxic if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Alphaxalone?

Alphaxalone is usually classified under HS code 291440 (Ketone-alcohols and ketone-aldehydes). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Alphaxalone?

CompoundList lists 24 suppliers of Alphaxalone in China, United States, Germany, Spain and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Alphaxalone?

Suppliers quote Alphaxalone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Alphaxalone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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