Hydroxyfasudil
Also known as Hydroxy-Fasudil, 5-((1,4-Diazepan-1-yl)sulfonyl)isoquinolin-1(2H)-one, 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine
Key facts
What buyers check first
- CAS number
- 105628-72-6
- Formula
- C14H17N3O3S
- Molar mass
- 307.38 g/mol
- HS code
- 293590
- Category
- Impurities and reference standards
What is Hydroxyfasudil?
Plain description, key identifiers and synonyms
Hydroxyfasudil is a chemical substance with the molecular formula C14H17N3O3S and a molar mass of 307.38 g/mol. Its CAS registry number is 105628-72-6. The IUPAC name is 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one
- CAS number
- 105628-72-6 CAS number cross-checked
- Molecular formula
- C14H17N3O3S
- UNII
- EYH4AU7P63
- MDL number
- MFCD01752417
- InChIKey
- ZAVGJDAFCZAWSZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H17N3O3S/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17/h1,3-5,7,15H,2,6,8-10H2,(H,16,18)
- SMILES (canonical and isomeric)
- C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O
Synonyms
- Hydroxy-Fasudil
- 5-((1,4-Diazepan-1-yl)sulfonyl)isoquinolin-1(2H)-one
- 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine
- 2erz
- 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one
- 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine
- 5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinolin-1-one
- 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-ol
- Fasudil Impurity 13
- HA 1100
- 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone
- HYDROXYFASUDIL, 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one
- 1(2H)-isoquinolinone, 5-((hexahydro-1H-1,4-diazepin-1-yl)sulfonyl)-
- 5-[(1,4-Diazepan-1-yl)sulfonyl]isoquinolin-1(2H)-one
- Fasudil Hydroxy
- 2etk
- 1-((1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl)hexahydro-1H-1,4-diazepine
- Fasudil Impurity L
- Hydroxyfasudil free base
- Hydroxyfasudil free base?
- Hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-1H-1,4-diazepine
- 1H-1,4-Diazepine, hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-
- 5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol
- 5-(1,4-Diazepane-1-sulfonyl)isoquinolin-1(2H)-one
- 5-(1,4-Diazepan-1-ylsulfonyl)-1(2H)-isoquinolinone
Show all 26 synonymsShow fewer synonyms
- 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydr o-1H-1,4-diazepine hydrochloride
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 307.38 g/molcalc.Computed value |
|---|---|
| Exact mass | 307.0991 Dacalc.Computed value |
| LogP (octanol/water) | 0.51calc.Computed value |
| Topological polar surface area | 82.27 Ųcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 4calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 21calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.36calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
![Murcko scaffold of this chemical, O=c1[nH]ccc2c(S(=O)(=O)N3CCCNCC3)cccc12](/scaffold/ZAVGJDAFCZAWSZ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]ccc2c(S(=O)(=O)N3CCCNCC3)cccc12
3 rings, 21 atoms. This chemical is the scaffold itself.
1 other chemical share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Hydroxyfasudil suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
Post one free request and suppliers who make or trade Hydroxyfasudil can send you quotes. Your contact details stay private until you accept a quote.
Hydroxyfasudil price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Hydroxyfasudil is traded under.
Sulphonamides, other
- United States23.6%
- Slovenia19.1%
- Spain11.7%
* Partner reported figures, a lower bound.
The HS code shown for Hydroxyfasudil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Salt and hydrate forms
Records that share this compound as their parent
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Same formula isomers
Different compounds that share this molecular formula
![3-(Dimethylaminomethylideneamino)-4-methoxy-2-thieno[2,3-b]pyridinecarboxylic acid ethyl ester chemical structure, C14H17N3O3S, CAS 341966-55-0](/s/MFSVYDYRFRBRLC-UHFFFAOYSA-N.svg)
![4-{3-[4-(Methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}piperidine chemical structure, C14H17N3O3S, CAS 849925-03-7](/s/OPQYOULELHGKEU-UHFFFAOYSA-N.svg)
![N-Cyclohexyl-2-{[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide chemical structure, C14H17N3O3S, CAS 350492-89-6](/s/TULOHQMLGNXALJ-UHFFFAOYSA-N.svg)
![Methyl 2-{3-oxo-1-[(phenylamino)thioxomethyl]piperazin-2-yl}acetate chemical structure, C14H17N3O3S, CAS 1008482-51-6](/s/GTLPHQUYEJAACF-UHFFFAOYSA-N.svg)
![Ethyl 4,5-dimethyl-2-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-3-thiophenecarboxylate chemical structure, C14H17N3O3S, CAS 293764-70-2](/s/MWJXAQQKHTYNRF-UHFFFAOYSA-N.svg)
![Benzamide, 2,6-dimethoxy-N-[5-(1-methylethyl)-1,3,4-thiadiazol-2-yl]- chemical structure, C14H17N3O3S, CAS 82559-72-6](/s/MOFQTPAHZWVYNY-UHFFFAOYSA-N.svg)
![N-[5-(Methoxymethyl)-1,3,4-thiadiazol-2-yl]-3-(4-methoxyphenyl)propanamide chemical structure, C14H17N3O3S, CAS 878430-11-6](/s/UAYKQKKVHJIAFP-UHFFFAOYSA-N.svg)
![2-[4-(4-Acetylphenyl)sulfonylpiperazin-1-yl]acetonitrile chemical structure, C14H17N3O3S, CAS 332375-06-1](/s/OTZQVPWNQQYNHQ-UHFFFAOYSA-N.svg)
![2-[[5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(4-methylpiperidin-1-yl)ethanone chemical structure, C14H17N3O3S, CAS 761422-06-4](/s/GCAZRHNPRLOQGK-UHFFFAOYSA-N.svg)
![2-[[5-(2-Methylfuran-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-piperidin-1-ylethanone chemical structure, C14H17N3O3S, CAS 879604-16-7](/s/CBTFRBKQPJAHOD-UHFFFAOYSA-N.svg)
Frequently asked questions
Quick answers about Hydroxyfasudil, based on the data on this page
What is Hydroxyfasudil?
What is the CAS number of Hydroxyfasudil?
What is the molecular formula and weight of Hydroxyfasudil?
Is Hydroxyfasudil hazardous?
What is the HS code of Hydroxyfasudil?
Where can I buy Hydroxyfasudil?
What is the price of Hydroxyfasudil?
Guides for buyers
Practical guides that help when you source, ship or handle Hydroxyfasudil
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
Get quotes for Hydroxyfasudil
Embed this structure on your websiteShow code
Paste this code into your page to show the 2D structure of Hydroxyfasudil with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.
<iframe src="https://www.compoundlist.com/embed/structure/hydroxyfasudil-105628-72-6" title="Hydroxyfasudil structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>Explore more in Impurities and reference standards or HS code 293590