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Skin conditioning agents and actives

Hydroxytyrosol

Also known as 3,4-Dihydroxyphenylethanol, 4-(2-hydroxyethyl)benzene-1,2-diol, 2-(3,4-Dihydroxyphenyl)ethanol

CAS 10597-60-1Formula C8H10O3Molar mass 154.17 g/molEC 600-704-3
GHS signal word: Warning. Pictograms: Harmful or irritant 106 suppliers listed
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Hydroxytyrosol chemical structure, C8H10O3, CAS 10597-60-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
10597-60-1
Formula
C8H10O3
Molar mass
154.17 g/mol
EC number
600-704-3
HS code
290729
Category
Skin conditioning agents and actives

What is Hydroxytyrosol?

Plain description, key identifiers and synonyms

Hydroxytyrosol is a member of the class of catechols that is benzene-1,2-diol substituted by a 2-hydroxyethyl group at position 4. Isolated from Olea europaea, it exhibits antioxidant and antineoplastic activities. It has a role as an antioxidant, a metabolite and an antineoplastic agent. It is a primary alcohol and a member of catechols. It is functionally related to a 2-(4-hydroxyphenyl)ethanol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-(2-hydroxyethyl)benzene-1,2-diol
CAS number
10597-60-1 CAS number cross-checked
EC number
600-704-3
Molecular formula
C8H10O3
UNII
QEU0NE4O90
MDL number
MFCD01320529
INCI name
HYDROXYTYROSOL
InChIKey
JUUBCHWRXWPFFH-UHFFFAOYSA-N
InChI
InChI=1S/C8H10O3/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,9-11H,3-4H2
SMILES (canonical and isomeric)
C1=CC(=C(C=C1CCO)O)O

Synonyms

  • 3,4-Dihydroxyphenylethanol
  • 4-(2-hydroxyethyl)benzene-1,2-diol
  • 2-(3,4-Dihydroxyphenyl)ethanol
  • 4-(2-hydroxyethyl)-1,2-Benzenediol
  • Homoprotocatechuyl alcohol
  • 3,4-DHPEA
  • 4-(3-hydroxypropyl)benzene-1,2-diol
  • dopet
  • 3,4-Dihydroxyphenethyl Alcohol
  • 3-Hydroxytyrosol
  • 3,4-Dihydroxyphenethylalcohol
  • 1,2-Benzenediol, 4-(2-hydroxyethyl)-
  • beta-3,4-Dihydroxyphenylethyl alcohol
  • 3,4-Dihydroxyphenyl ethanol
  • 3,4-dihydroxy-1-benzeneethanol
  • hydroxy tyrosol
  • Hydroxy Tyrosol (>85%)
  • 2-(3,4-Dihydroxyphenyl)ethyl Alcohol
  • Hydroxy Tyrosol-d3
  • hydroxytyrol
  • 4-(2-Hydroxy-ethyl)-benzene-1,2-diol
  • Hydroxytyrosol (Standard)
  • 3,4-dihydroxy-phenylethanol
  • 3-Hydroxytyrosol - Technical
  • 3,4-dihydroxyphenylethyl alcohol
Show all 32 synonyms
  • Juubchwrxwpffh-uhfffaoysa-
  • 2-(3,4-dihydroxyphenyl) ethanol
  • Ba 2774
  • 2-(3,4-dihydroxy-phenyl)-ethanol
  • 1,2-benzenediol-4-(2-hydroxyethyl)
  • 3-Hydroxytyrosol, >=98% (HPLC)
  • 3-Hydroxytyrosol, analytical standard

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
154.17 g/molcalc.
Exact mass
154.063 Dacalc.
LogP (octanol/water)
0.63calc.
Topological polar surface area
60.69 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Hydroxytyrosol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 106 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

106 suppliers in 16 countries

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Hydroxytyrosol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name HYDROXYTYROSOL(bleaching, skin conditioning)

Pharmacological actions

  • Anti-Infective Agents
  • Antioxidants
  • Platelet Aggregation Inhibitors

Roles

  • antineoplastic agent
  • antioxidant
  • metabolite
  • pharmaceutical

Functional uses

  • Bleaching agent
  • Softener and conditioner

Cosmetic functions

  • Bleaching
  • Skin conditioning

Pharmacology

Hydroxytyrosol is a phenolic phytochemical naturally occurring in extra virgin olive oil, with potential antioxidant, anti-inflammatory and cancer preventive activities. Although the mechanisms of action through which hydroxytyrosol exerts its effects have yet to be fully determined, this agent affects the expression of various components of the inflammatory response, possibly through the modulation of the nuclear factor-kappa B (NF-kB) pathway.

Read more

The effects include the modulation of pro-inflammatory cytokines, such as the inhibition of interleukin-1alpha (IL-1a), IL-1beta, IL-6, IL-12, and tumor necrosis factor-alpha (TNF-a), increased secretion of the anti-inflammatory cytokine IL-10, inhibition of the production of certain chemokines, such as C-X-C motif chemokine ligand 10 (CXCL10/IP-10), C-C motif chemokine ligand 2 (CCL2/MCP-1), and macrophage inflammatory protein-1beta (CCL4/MIP-1b), and inhibition of the expression of the enzymes inducible nitric oxide synthase (iNOS/NOS2) and prostaglandin E2 synthase (PGES), which prevent the production of nitric oxide (NO) and prostaglandin E (PGE2), respectively. In addition, hydroxytyrosol is able to regulate the expression of other genes involved in the regulation of tumor cell proliferation, such as extracellular signal-regulated and cyclin-dependent kinases. Also, hydroxytyrosol scavenges free radicals and prevents oxidative DNA damage. This induces apoptosis and inhibits proliferation in susceptible cancer cells.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxytyrosol is traded under.

HS 2907.29Indicative HS code

Polyphenols, phenol-alcohols, other

World exports in 2024
$535M
−27.0% vs 2023, imports $565M
2019 to 2024
Top exporters
  1. India * partner reported17.7%
  2. Germany16.5%
  3. Japan15.8%
Top importers
  1. United States13.1%
  2. Japan8.0%
  3. Belgium7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxytyrosol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxytyrosol, based on the data on this page

What is Hydroxytyrosol?

Hydroxytyrosol is a member of the class of catechols that is benzene-1,2-diol substituted by a 2-hydroxyethyl group at position 4. Isolated from Olea europaea, it exhibits antioxidant and antineoplastic activities. It has a role as an antioxidant, a metabolite and an antineoplastic agent.

What is the CAS number of Hydroxytyrosol?

The CAS registry number of Hydroxytyrosol is 10597-60-1.

What is the molecular formula and weight of Hydroxytyrosol?

The molecular formula of Hydroxytyrosol is C8H10O3 and its molar mass is 154.17 g/mol.

What is Hydroxytyrosol used for?

Known uses and roles of Hydroxytyrosol include antioxidants in cosmetics and personal care, skin conditioning agents in cosmetics and personal care, antineoplastic agent, antioxidant, metabolite and 8 more.

Is Hydroxytyrosol hazardous?

Hydroxytyrosol carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Hydroxytyrosol?

Hydroxytyrosol is usually classified under HS code 290729 (Polyphenols, phenol-alcohols, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxytyrosol?

CompoundList lists 106 suppliers of Hydroxytyrosol in China, United States, Germany, Spain and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Hydroxytyrosol in India?

2 suppliers in India list Hydroxytyrosol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Hydroxytyrosol?

Suppliers quote Hydroxytyrosol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxytyrosol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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