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Amino acids and derivatives

Hypusine

Also known as (+)-hypusine, N(6)-(4-Amino-2-hydroxybutyl)-L-lysine, (R)-N6-(4-amino-2-hydroxybutyl)-l-lysine

CAS 34994-11-1Formula C10H23N3O3Molar mass 233.31 g/mol
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Hypusine chemical structure, C10H23N3O3, CAS 34994-11-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
34994-11-1
Formula
C10H23N3O3
Molar mass
233.31 g/mol
HS code
292250
Category
Amino acids and derivatives

What is Hypusine?

Plain description, key identifiers and synonyms

Hypusine is an L-lysine derivative that is L-lysine bearing a (2R)-4-amino-2-hydroxybutyl substituent at position N6. It is a L-lysine derivative and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of a hypusinate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-2-amino-6-[[(2R)-4-amino-2-hydroxybutyl]amino]hexanoic acid
CAS number
34994-11-1 CAS number cross-checked
Molecular formula
C10H23N3O3
UNII
3874VXF092
InChIKey
BZUIJMCJNWUGKQ-BDAKNGLRSA-N
InChI
InChI=1S/C10H23N3O3/c11-5-4-8(14)7-13-6-2-1-3-9(12)10(15)16/h8-9,13-14H,1-7,11-12H2,(H,15,16)/t8-,9+/m1/s1
Canonical SMILES
NCCC(O)CNCCCCC(N)C(=O)O
Isomeric SMILES
C(CCNC[C@@H](CCN)O)C[C@@H](C(=O)O)N

Synonyms

  • (+)-hypusine
  • N(6)-(4-Amino-2-hydroxybutyl)-L-lysine
  • (R)-N6-(4-amino-2-hydroxybutyl)-l-lysine
  • (2S)-2-amino-6-(((2S)-4-amino-2-hydroxybutyl)amino)hexanoic acid
  • L-Lysine, N6-[(2R)-4-amino-2-hydroxybutyl]-
  • (2S)-2-amino-6-[[(2R)-4-amino-2-hydroxybutyl]amino]hexanoic acid
  • N6-((R)-4-amino-2-hydroxybutyl)-L-lysine
  • L-Lysine, n6-((2R)-4-amino-2-hydroxybutyl)-
  • 34994-11-1 (free base)
  • (2S,9R)-2,11-diamino-9-hydroxy-7-azaundecanoic acid
  • N(6)-[(2R)-4-amino-2-hydroxybutyl]-L-lysine
  • L-Lysine, N6-(4-amino-2-hydroxybutyl)-, (R)-
  • N~6~-[(2R)-4-Amino-2-hydroxybutyl]-L-lysine
  • (S)-2-Amino-6-(((R)-4-amino-2-hydroxybutyl)amino)hexanoic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
233.31 g/molcalc.
Exact mass
233.1739 Dacalc.
LogP (octanol/water)
-1.13calc.
Topological polar surface area
121.6 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
10calc.
Heavy atoms
16calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.9calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Hypusine suppliers

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Hypusine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hypusine is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hypusine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hypusine, based on the data on this page

What is Hypusine?

Hypusine is an L-lysine derivative that is L-lysine bearing a (2R)-4-amino-2-hydroxybutyl substituent at position N6. It is a L-lysine derivative and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of a hypusinate.

What is the CAS number of Hypusine?

The CAS registry number of Hypusine is 34994-11-1.

What is the molecular formula and weight of Hypusine?

The molecular formula of Hypusine is C10H23N3O3 and its molar mass is 233.31 g/mol.

Is Hypusine hazardous?

No GHS hazard classification for Hypusine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Hypusine?

Hypusine is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hypusine?

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What is the price of Hypusine?

Suppliers quote Hypusine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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