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Emollients

Icosapent

Also known as EPA, Icosapento, Icosapentum

CAS 10417-94-4Formula C20H30O2Molar mass 302.46 g/molEC 600-528-7
GHS signal word: Danger. Pictograms: Corrosive 64 suppliers listed Drug substance
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Icosapent chemical structure, C20H30O2, CAS 10417-94-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
10417-94-4
Formula
C20H30O2
Molar mass
302.46 g/mol
EC number
600-528-7
HS code
291619
Category
Emollients

What is Icosapent?

Plain description, key identifiers and synonyms

All-cis-5,8,11,14,17-icosapentaenoic acid is an icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17. It has a role as a micronutrient, an antidepressant, an antineoplastic agent, an anticholesteremic drug, a nutraceutical, a mouse metabolite, a fungal metabolite and a Daphnia galeata metabolite. It is an omega-3 fatty acid and an icosapentaenoic acid. It is a conjugate acid of an all-cis-5,8,11,14,17-icosapentaenoate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid
CAS number
10417-94-4 CAS number cross-checkedOther or deprecated CAS: 25377-48-4
EC number
600-528-7
Molecular formula
C20H30O2
UNII
AAN7QOV9EA
MDL number
MFCD00065716
INCI name
EICOSAPENTAENOIC ACID
InChIKey
JAZBEHYOTPTENJ-JLNKQSITSA-N
InChI
InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-
Canonical SMILES
CCC=CCC=CCC=CCC=CCC=CCCCC(=O)O
Isomeric SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O

Synonyms

  • EPA
  • Icosapento
  • Icosapentum
  • Miraxion
  • Eye Q
  • Eye-Q
  • Ropufa 70
  • Incromega e 7010sr
  • C20:5 (n-3)
  • (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate
  • C20:5n-3,6,9,12,15
  • Icosapentum (INN-Latin)
  • Icosapento (INN-Spanish)
  • Reliven
  • EPA-FFA
  • Icosapent (epa)
  • icosapentate
  • Timnodonic acid
  • cis-5,8,11,14,17-Eicosapentaenoic acid
  • (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid
  • (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid
  • eicosapentaenoate
  • 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid
  • (all-Z)-5,8,11,14,17-Eicosapentaenoic acid
  • Icosapentaenoate
Show all 35 synonyms
  • (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid
  • Eicosapentaenoic acid (c20:5 n3)
  • FA 20:5
  • 5,8,11,14,17-Icosapentaenoic acid
  • (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid
  • all-cis-5,8,11,14,17-eicosapentaenoic acid
  • all-cis-icosa-5,8,11,14,17-pentaenoic acid
  • Icosapent (INN)
  • cis-Delta(5,8,11,14,17)-eicosapentaenoic acid
  • 5,8,11,14,17-Eicosapentaenoic acid, (all-Z)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
302.46 g/molcalc.
Exact mass
302.2246 Dacalc.
LogP (octanol/water)
5.99calc.
Topological polar surface area
37.3 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
13calc.
Heavy atoms
22calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.45calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive

Hazard statements

  • H314Causes severe skin burns and eye damage.
Precautionary statements (12)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P363Wash contaminated clothing before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Icosapent suppliers

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All 64 suppliers
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Where suppliers are based

64 suppliers in 13 countries

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Icosapent price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name EICOSAPENTAENOIC ACID(skin conditioning - emollient, skin conditioning)

Roles

  • Daphnia galeata metabolite
  • anti-asthmatic agent
  • anti-inflammatory agent
  • anti-obesity agent
  • anticholesteremic drug
  • anticonvulsant
  • antidepressant
  • antilipemic drug
  • antineoplastic agent
  • antipsychotic agent
  • antirheumatic drug
  • antiviral agent
  • cardiovascular drug
  • central nervous system drug
  • fungal metabolite
  • gastrointestinal drug
  • geroprotector
  • immunomodulator
  • immunosuppressive agent
  • micronutrient
  • mouse metabolite
  • nutraceutical
  • pharmaceutical
  • renoprotective agent

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning
  • Skin conditioning - emollient

Pharmacology

Icosapent is the free fatty acid (FFA) form of eicosapentaenoic acid (EPA), a polyunsaturated long-chain fatty acid found in fish oil with a 20-carbon backbone and 5 double bonds, with potential supplementing, anti-inflammatory, anti-thrombotic, immunomodulating, anti-angiogenic and chemopreventive activities. Upon administration of icosapent, the free form of EPA is incorporated in cell membrane phospholipids and replaces arachidonic acid. This inhibits arachidonic acid conversion into thromboxanes and prostaglandin E2 (PGE2). Upon oral administration of icosapent, the EPA-FFA prevents and suppresses colonic neoplasia and reduces polyp formation and growth through as of yet not fully elucidated mechanisms.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Icosapent is traded under.

HS 2916.19Indicative HS code

Unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides…

World exports in 2024
$674M
−9.6% vs 2023, imports $722M
2019 to 2024
Top exporters
  1. China44.5%
  2. Germany15.3%
  3. India * partner reported11.5%
Top importers
  1. United States17.1%
  2. Netherlands7.8%
  3. South Korea7.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Icosapent is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Icosapent, based on the data on this page

What is Icosapent?

All-cis-5,8,11,14,17-icosapentaenoic acid is an icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.

Is Icosapent hazardous?

Icosapent carries the GHS signal word "Danger". Main hazards: causes severe skin burns and eye damage. This summary is not an SDS, always read the supplier safety data sheet.

Guides for buyers

Practical guides that help when you source, ship or handle Icosapent

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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