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Antibiotics and anti-infectives

Imipenem

Also known as Imipemide, N-Formimidoylthienamycin, Imipenem anhydrous

CAS 64221-86-9Formula C12H17N3O4SMolar mass 299.35 g/molEC 264-734-5
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Imipenem chemical structure, C12H17N3O4S, CAS 64221-86-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
64221-86-9
Formula
C12H17N3O4S
Molar mass
299.35 g/mol
EC number
264-734-5
HS code
294190
Category
Antibiotics and anti-infectives

What is Imipenem?

Plain description, key identifiers and synonyms

Imipenem is a broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup. It has a role as an antibacterial drug. It is a member of carbapenems and a beta-lactam antibiotic allergen. It is a tautomer of an imipenem zwitterion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CAS number
64221-86-9 CAS number cross-checkedOther or deprecated CAS: 74431-23-5
EC number
264-734-5
Molecular formula
C12H17N3O4S
UNII
Q20IM7HE75
MDL number
MFCD00864955
InChIKey
ZSKVGTPCRGIANV-ZXFLCMHBSA-N
InChI
InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1
Canonical SMILES
CC(O)C1C(=O)N2C(C(=O)O)=C(SCCN=CN)CC12
Isomeric SMILES
C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O

Synonyms

  • Imipemide
  • N-Formimidoylthienamycin
  • Imipenem anhydrous
  • Imipenemum
  • N-formimidoyl thienamycin
  • (5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • MK 0787
  • Anhydrous Imipenem
  • Imipenem, Anhydrous
  • (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure
  • (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • Recarbrio component imipenem
  • (5R,6S)-3-((2-((E)-(aminomethylidene)amino)ethyl)sulfanyl)-6-((1R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6S)-3-(2-(aminomethylideneamino)ethylsulfanyl)-6-((1R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • Anhydrous, Imipenem
  • N Formimidoylthienamycin
  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, monohydrate, (5R-(5alpha,6alpha(R*)))-
  • (5R,6S)-3-(2-(aminomethylideneazaniumyl)ethylsulfanyl)-6-((1R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate
  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))-
  • Imipenem monohydrate (h2o)
  • Imipenem, N-Formimidoyl thienamycin
  • Imipenem (INN)
Show all 36 synonyms
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid,6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-,(5R,6S)-
  • Imipenen
  • (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[(2-methanimidamidoethyl)sulfanyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6S)-3-((2-formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • imipen
  • Imipenem CRS
  • (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-(2-methanimidamidoethylsulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-((1R)-1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R,6S)-
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-
  • Imipenem (anhydrous)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
299.35 g/molcalc.
Exact mass
299.094 Dacalc.
LogP (octanol/water)
-0.39calc.
Topological polar surface area
116.2 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
6calc.
Heavy atoms
20calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.58calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC2CC=CN12

O=C1CC2CC=CN12

2 rings, 8 atoms, the 1-Azabicyclo[3.2.0]hept-2-en-7-one ring system.

63 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Imipenem suppliers

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Where suppliers are based

59 suppliers in 13 countries

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Imipenem price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • pharmaceutical

Pharmacology

Imipenem anhydrous is a Penem Antibacterial.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Imipenem is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Imipenem is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Imipenem, based on the data on this page

What is Imipenem?

Imipenem is a broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup. It has a role as an antibacterial drug. It is a member of carbapenems and a beta-lactam antibiotic allergen. It is a tautomer of an imipenem zwitterion.

What is the CAS number of Imipenem?

The CAS registry number of Imipenem is 64221-86-9. Other or deprecated CAS numbers: 74431-23-5.

What is the molecular formula and weight of Imipenem?

The molecular formula of Imipenem is C12H17N3O4S and its molar mass is 299.35 g/mol.

What is Imipenem used for?

Known uses and roles of Imipenem include antibacterials and antibiotics in pharmaceuticals, antibacterial agent, antibacterial drug, antiinfective agent, antimicrobial agent and 3 more.

Is Imipenem hazardous?

No GHS hazard classification for Imipenem is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Imipenem?

Imipenem is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Imipenem?

CompoundList lists 59 suppliers of Imipenem in United States, China, Spain, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Imipenem in India?

1 supplier in India list Imipenem on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Imipenem?

Suppliers quote Imipenem on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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